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Composition with function of adjusting constitution proportion of lipoprotein cholesterol and application thereof

A proportional action, cholesterol technology, applied in the application field of the food field, can solve the problems such as the reduction of serum HDL-C level, side effects, and the drug can not achieve the ideal therapeutic effect, and achieve the effect of mild effect, reliable safety, and lowering blood lipid level.

Inactive Publication Date: 2015-01-07
云南白药天颐茶品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Clinically, chemical monomer drug preparations such as statins and fibrates are usually used to regulate the concentration of lipoproteins in serum by reducing blood lipid indicators, but some drugs cannot achieve the desired therapeutic effect, such as: in animal and human experiments It has been proved that probucol has the effect of lowering TC (total cholesterol) and LDL-C (low-density lipoprotein cholesterol), but at the same time it can reduce the level of serum HDL-C (high-density lipoprotein cholesterol), which regulates blood lipids. The mechanism is not yet clear
Although chemical drugs have a clear structure and function, they often bring certain side effects, and the metabolic changes caused by some chemical drugs can only be discovered after long-term clinical use and feedback

Method used

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  • Composition with function of adjusting constitution proportion of lipoprotein cholesterol and application thereof
  • Composition with function of adjusting constitution proportion of lipoprotein cholesterol and application thereof
  • Composition with function of adjusting constitution proportion of lipoprotein cholesterol and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A composition capable of regulating the composition ratio of lipoprotein cholesterol is composed of 3 parts of balsam pear, 1 part of lotus leaf, 2 parts of cassia seed, 1 part of licorice, 0.2 part of brown rice and 5 parts of resistant dextrin. After weighing each raw material according to the amount of the recipe, the plant raw materials are cleaned, sorted, crushed, and sieved to take 80-100 mesh particles and mix them evenly with dietary fiber. Add appropriate amount of starch to granulate and pack to make bags Tea.

Embodiment 2

[0032] A composition capable of regulating the composition ratio of lipoprotein cholesterol is composed of 8 kg of bitter gourd, 6 kg of lotus leaves, 5 kg of cassia seeds, 5 kg of oolong tea, 3 kg of licorice, 3 kg of brown rice, 3 kg of bamboo shoots and 15 kg of inulin. Weigh each material according to the formula, take balsam pear, lotus leaf, cassia seed, oolong tea, licorice, and bamboo shoots after net selection, add 8 times pure water and boil for 0.5 hours, extract twice, and combine the two extracts after 5000r / Centrifuge for 1 min, then filter at 1um, concentrate the filtrate to make a concentrated solution with a solid content of 10%; extract brown rice separately: add 8 times boiling water to extract for 0.2 hours, and filter the extract at 1um to obtain the brown rice extract. Take the concentrated solution, add brown rice extract, add inulin, add 6kg of white sugar, add water to 1000kg, filter through 1um, and the filtrate is sterilized at 137°C for 10 seconds a...

Embodiment 3

[0034] A composition capable of regulating the composition ratio of lipoprotein cholesterol, comprising 5 parts of bitter gourd, 4 parts of lotus leaf, 3 parts of cassia seed, 2 parts of tea, 2 parts of licorice, 0.8 part of brown rice, 4 parts of fructooligosaccharide, and resistant dextrin Makes 4 servings. Weigh each material according to the formula, take bitter gourd, lotus leaf, cassia seed, tea leaves, and licorice after cleaning, add 15 times of pure water to boil for 1 hour, extract twice, and the extract is centrifuged at 6000r / min. After 5um filtration, the filtrate is concentrated and made into an extract with a density of 1.15; the brown rice is extracted separately: add 15 times boiling water to extract for 0.5 hours, and the extract is filtered at 5um to obtain a brown rice extract, which is concentrated to a density of 1.15 extract, mix the two extracts evenly. The extract is evenly mixed with fructooligosaccharide and resistant dextrin, and sucrose is added i...

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Abstract

The invention relates to a composition which is prepared through the compatibility of medicinal and edible homologous materials and has the functions of reducing the level of blood fat and adjusting the constitution proportion of lipoprotein cholesterol in serum and application of the composition in the field of food. The composition disclosed by the invention is mainly prepared from the following components in parts by weight: 3-8 parts of balsam pear, 1-6 parts of lotus leaf, 2-5 parts of semen cassiae, 1-3 parts of licorice root, 0.2-3 parts of shelled rice, and 5-15 parts of dietary fiber, or the extracts of the components, wherein the balsam pears, the lotus leaves, the semen cassiae, the licorice roots and the shelled rice are dry plant products. The extraction method comprises the following steps: taking and mixing the balsam pears, the lotus leaves, the semen cassiae and the licorice roots, adding pure water of which the weight is 8-15 times of the weight of the mixed components, boiling the mixed components in the water, performing extraction for 0.5-1 hour, and performing the extraction for 1-3 times, performing centrifugation with 5000-6000r / min on an extracting solution, performing filtration of 1-5 [mu]m, concentrating filtrate to obtain a concentrated solution of which the solid content is 10-20%, or directly concentrating the filtrate to obtain extractum of which the density is 1.15-1.25 at the temperature of 65-70 DEG C, and independently extracting the shelled rice.

Description

technical field [0001] The invention relates to a composition which is made by the compatibility of medicinal and food homologous materials and has the functions of reducing blood lipid level and regulating the composition ratio of lipoprotein cholesterol in serum, and its application in the field of food. technical background [0002] With the improvement of living standards, people's dietary structure and habits are also gradually evolving. Excessive intake of cholesterol leads to an upward trend in diseases such as cardiovascular system. Long-term excessive food cholesterol intake will cause hypercholesterolemia, And then form the so-called "rich man's disease" such as coronary atherosclerotic heart disease. Cholesterol exists in the form of lipoproteins in the blood, and there are mainly six kinds of lipoprotein particles, among which low-density lipoprotein (LDL) and high-density lipoprotein (HDL) appear more and more in popular science materials such as daily health ca...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/09A23F3/14A23F3/34A23L33/105A23L33/21
CPCA23L33/21A23L33/105A23V2002/00A23V2200/3262A23V2250/21A23V2250/5114A23V2250/214A23V2250/28A23V2250/5072
Inventor 王明辉韦建荣马银海王丽娜宗青云黄卫东姚坤华熊文君
Owner 云南白药天颐茶品有限公司