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Processing technology for Cefoperazone sodium tazobactam sodium for injection

A technology of tazobactam sodium and cefoperazone sodium, applied in the field of medicine and biology, can solve the problems of ineffective saving of time and economic cost, complex processing technology, etc., and achieve the effect of saving time and economic cost, simple processing technology and low cost

Inactive Publication Date: 2015-03-04
SICHUAN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the processing technology of existing injection cefoperazone sodium tazobactam sodium is complicated, can not effectively save time and economic cost

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The processing technology of cefoperazone sodium tazobactam sodium for injection comprises the following steps:

[0020] (1) Dried raw materials of cefoperazone sodium and tazobactam sodium;

[0021] (2) Then mix cefoperazone sodium and tazobactam sodium with a multi-directional powder mixer according to the formula ratio;

[0022] (3) Wash the antibiotic bottle for powder, dry and sterilize for use;

[0023] (4) Divide the mixed cefoperazone sodium and tazobactam sodium into prepared antibiotic bottles for crimping, and perform light inspection and packaging after crimping.

[0024] After the powder is mixed, it needs to be sieved.

[0025] The sieved cefoperazone sodium and tazobactam sodium are 80-200 mesh raw material powders.

[0026] The humidity conditions of the processing technology are 20-30%, and the temperature is 18-26°C.

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PUM

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Abstract

The invention discloses a processing technology for cefoperazone sodium tazobactam sodium for injection. The processing technology includes: firstly drying cefoperazone sodium raw material and tazobactam sodium raw material, then conducting powder mixing, finally subpackaging the well mixed cefoperazone sodium and tazobactam sodium antibiotic with well prepared antibiotic bottles, carrying out cover pressing treatment, and then performing light inspection packaging. The processing process is simple and is low in cost, can effectively save time and economic cost, and can reduce the labor intensity of workers.

Description

[0001] technical field [0002] The invention relates to the field of medical biology, in particular to a processing technology of cefoperazone sodium and tazobactam sodium for injection. Background technique [0003] The Chinese alias of cefoperazone sodium is 7-(((4-ethyl-2,3-dioxo-1-piperazinyl)formylamino)(4-hydroxyphenyl)acetamido)-3-((1-methyl Base-1H-tetrazol-5-yl)thiomethyl)-8-oxo-5-thio-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid sodium salt, produced by negative bacillus The broad-spectrum β-lactamase has a certain stability, but it is worse than some third-generation cephalosporins. antibacterial activity. The effect of anti-positive bacteria is not as good as the first and second generation cephalosporins, but it has a better effect on pneumococcus and streptococcus pyogenes. The antibacterial effect on anaerobic bacteria is weak. Enterococci and a considerable proportion of Enterobacteriaceae pathogens are resistant to this product, and Mycoplasma, Chlamy...

Claims

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Application Information

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IPC IPC(8): A61K31/546A61K9/14A61P31/04A61K31/431
CPCA61K31/546A61K9/0019A61K9/14A61K31/431A61K2300/00
Inventor 包莹刘萍陈继源
Owner SICHUAN PHARMA
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