Cerebrolysin hydrolysate injection and preparation method thereof
A technology of cerebroprotein hydrolyzate and injection, which is applied in the field of cerebroprotein hydrolyzate injection and its preparation, can solve problems such as anaphylactic shock, and achieve the effect of reducing the degree of allergic reaction
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Embodiment 1
[0011] Example 1 Preparation method of cerebroprotein hydrolyzate injection: ①Take healthy fresh pig brain, remove fat, homogenate, evacuate to 8Pa, keep the pressure for 10min, and then inject CO 2 To a pressure of 15Pa, keep the pressure for 20min; ②At 400rpm, slowly add the brain plasma in ① to 7 times its liquid CO 2 After the addition, stir for 50 minutes, cool down to -75°C, keep it for 3 hours, then raise the temperature to 45°C within 8 minutes, put CO 2 Gasification; ③ Add 3 times the weight of water for injection to step ②, stir evenly, then add papain or pepsin equivalent to 0.7% of the weight of frozen brain pulp, and hydrolyze at 37°C for 3.5 hours to obtain an enzymatic hydrolyzate; ④ Centrifuge the enzymatic hydrolyzate at 2500rpm for 25min, take the supernatant, take 100ml of the supernatant and the total nitrogen content is 6g (refer to the WS1-X-018-2001Z quality standard to detect the total nitrogen content), add 10ml of HS-15, in Activated carbon adsorpt...
Embodiment 2
[0012] Example 2 Preparation method of cerebroprotein hydrolyzate injection: ①Take healthy fresh pig brain, remove fat, homogenate, evacuate to 8Pa, keep the pressure for 10min, and then inject CO 2 To a pressure of 15Pa, keep the pressure for 20min; ②At 400rpm, slowly add the brain plasma in ① to 7 times its liquid CO 2 After the addition, stir for 50 minutes, cool down to -75°C, keep it for 3 hours, then raise the temperature to 45°C within 8 minutes, put CO 2 Gasification; ③ Add 3 times the weight of water for injection to step ②, stir evenly, then add papain or pepsin equivalent to 0.7% of the weight of frozen brain pulp, and hydrolyze at 37°C for 3.5 hours to obtain an enzymatic hydrolyzate; ④ Centrifuge the hydrolyzate at 2500rpm for 25min, take the supernatant, take 100ml of the supernatant and the total nitrogen content is 6g (refer to the WS1-X-018-2001Z quality standard to detect the total nitrogen content), add 50ml of HS-15, in Activated carbon adsorption at roo...
Embodiment 3
[0013] Example 3 Preparation method of cerebroprotein hydrolyzate injection: ①Take healthy fresh pig brain, remove fat, homogenate, evacuate to 8Pa, keep the pressure for 10min, and then inject CO 2 To a pressure of 15Pa, keep the pressure for 20min; ②At 400rpm, slowly add the brain plasma in ① to 7 times its liquid CO 2 After the addition, stir for 50 minutes, cool down to -75°C, keep it for 3 hours, then raise the temperature to 45°C within 8 minutes, put CO 2 Gasification; ③ Add 3 times the weight of water for injection to step ②, stir evenly, then add papain or pepsin equivalent to 0.7% of the weight of frozen brain pulp, and hydrolyze at 37°C for 3.5 hours to obtain an enzymatic hydrolyzate; ④ Centrifuge the hydrolyzate at 2500rpm for 25min, take the supernatant, take 100ml of the supernatant and the total nitrogen content is 6g (refer to the WS1-X-018-2001Z quality standard to detect the total nitrogen content), add 100ml of HS-15, in Activated carbon adsorption at r...
PUM

Abstract
Description
Claims
Application Information

- Generate Ideas
- Intellectual Property
- Life Sciences
- Materials
- Tech Scout
- Unparalleled Data Quality
- Higher Quality Content
- 60% Fewer Hallucinations
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com