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Traditional Chinese medicine oral liquid for treating avian influenza and preparation method thereof

A technology for avian influenza and traditional Chinese medicine oral liquid, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, and drug delivery, etc., can solve the problems of reduced vaccine effectiveness, increased drug-resistant strains, and impact on influenza control, and achieves It is not easy to produce drug resistance, has no toxic side effects, and is easy to store.

Inactive Publication Date: 2015-05-27
TIANJIN ZHONGAO BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinical prevention and treatment mainly focus on vaccines and antiviral drugs. Vaccines are an effective means of inhibiting influenza virus, but it takes a long time from vaccine injection to the production of protective antibodies. More importantly, due to the The antigenic variability of the vaccine significantly reduces the effectiveness of the vaccine, which often affects the effectiveness of influenza control
These deficiencies of the vaccine make the research on anti-avian influenza virus drugs very necessary, they can play the role of prevention and treatment at the same time, thereby reducing the threat of avian influenza virus to the greatest extent, currently used in clinical antibacterial, anti-avian Viruses, vaccines, etc., but due to the complexity of the etiology, it is often difficult to receive good results
Moreover, due to the abuse of antibiotics, the drug-resistant strains are increasing day by day, and the residues of drugs in the body become a threat to human health.

Method used

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  • Traditional Chinese medicine oral liquid for treating avian influenza and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A traditional Chinese medicine oral liquid for treating avian influenza. The components and weights of the traditional Chinese medicine oral liquid are: 10g of honeysuckle; 100g of forsythia; 50g of Radix Radix; 10g of dandelion; 100g of Qingdai; 100g of licorice;

[0028] A preparation method of a traditional Chinese medicine oral liquid for treating avian influenza, the steps of the preparation method are as follows:

[0029] (1) Weigh honeysuckle, forsythia, isatis root, dandelion, indigo naturalis, licorice and raw gypsum respectively according to the weight ratio, and grind them;

[0030] (2) Soak the crushed honeysuckle, forsythia, isatidis, dandelion, indigo naturalis, licorice and raw gypsum in step (1) in water for one hour and then decoct three times, each time adding 5-12 times the total amount of medicinal materials, each Decoct for 0.5-1 hour, combine the decoction, filter, combine the filtrate, and concentrate to a relative density of 1.01-1.03. Add 95% e...

Embodiment 2

[0033] A traditional Chinese medicine oral liquid for treating avian influenza. The components and weights of the traditional Chinese medicine oral liquid are: 100g of honeysuckle; 200g of forsythia; 300g of Radix Radix; 100g of dandelion; 200g of Qingdai; 300g of licorice;

[0034] A preparation method of a traditional Chinese medicine oral liquid for treating avian influenza, the steps of the preparation method are as follows:

[0035] (1) Weigh honeysuckle, forsythia, isatis root, dandelion, indigo naturalis, licorice and raw gypsum respectively according to the weight ratio, and grind them;

[0036] (2) Soak the crushed honeysuckle, forsythia, isatidis, dandelion, indigo naturalis, licorice and raw gypsum in step (1) in water for one hour and then decoct three times, each time adding 5-12 times the total amount of medicinal materials, each Decoct for 0.5-1 hour, combine the decoction, filter, combine the filtrate, and concentrate to a relative density of 1.01-1.03. Add 95...

Embodiment 3

[0039] A traditional Chinese medicine oral liquid for treating avian influenza. The components and weights of the Chinese medicinal oral liquid are: 50g of honeysuckle; 150g of forsythia; 200g of Radix Radix; 75g of dandelion; 150g of Qingdai; 150g of licorice;

[0040] A preparation method of a traditional Chinese medicine oral liquid for treating avian influenza, the steps of the preparation method are as follows:

[0041] (1) Weigh honeysuckle, forsythia, isatis root, dandelion, indigo naturalis, licorice and raw gypsum respectively according to the weight ratio, and grind them;

[0042] (2) Soak the crushed honeysuckle, forsythia, isatidis, dandelion, indigo naturalis, licorice and raw gypsum in step (1) in water for one hour and then decoct three times, each time adding 5-12 times the total amount of medicinal materials, each Decoct for 0.5-1 hour, combine the decoction, filter, combine the filtrate, and concentrate to a relative density of 1.01-1.03. Add 95% ethanol to ...

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Abstract

The invention relates to a traditional Chinese medicine oral liquid for treating avian influenza and a preparation method thereof. The traditional Chinese medicine oral liquid comprises the following ingredients, by weight, 1-10 parts of honeysuckle flower, 10-20 parts of fructus forsythia, 5-30 parts of isatis root, 1-10 parts of dandelion, 10-20 parts of natural indigo, 10-30 parts of licorice and 5-10 parts of gypsum. The traditional Chinese medicine oral liquid has heat-clearing, detoxifying, anti-inflammation, cough-relieving and antiviral effects, has little toxic and side effect, is not easy to generate drug resistance, has high bioavailability, has no drug residue, meets requirements of safe veterinary drug and animal-derived food safety guarantee, and is an ideal traditional Chinese medicine oral liquid for treating avian influenza.

Description

technical field [0001] The invention belongs to the field of veterinary medicine, in particular to a traditional Chinese medicine oral liquid for treating avian influenza and a preparation method thereof. Background technique [0002] Avian influenza (avian influenza, AI), referred to as bird flu. It is a disease mainly affecting the respiratory system caused by influenza A virus. Due to the variability of AIV antigenicity and pathogenicity and the lack of cross-protection between different serotypes, avian influenza has been prevalent around the world for more than 100 years, seriously endangering human health and the development of animal husbandry, especially in recent years. The outbreak of bird flu has caused huge losses to the poultry industry all over the world. [0003] The main clinical manifestations of avian influenza are crown beard cyanosis, hemorrhage, swollen head and tears, dyspnea, failure and death, decreased egg production, and some cases may show obviou...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/634A61K36/704A61K9/08A61P31/16A61K33/06
Inventor 陈庆忠安同伟刘芳
Owner TIANJIN ZHONGAO BIOTECH
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