Simultaneous determination method for nicotine, 1,2-propylene glycol and glycerol in electronic cigarette smoke

Abstract

The invention discloses a simultaneous determination method for nicotine, 1,2-propylene glycol and glycerol in electronic cigarette smoke. The method comprises the following steps: smoking an electronic cigarette according to a smoking scheme; capturing the smoke by using a glass fiber filter; after extraction oscillation is performed on the fiber filter by adopting internal standard-containing organic solution, taking 1mL of solution in a 2mL chromatogram bottle; detecting extracted solution through a gas chromatography-hydrogen flame detector. According to the method, a DB-ALC1 (30m*0.32mm*1.8 mum) chromatographic column is adopted, so simultaneous analysis of high-concentration 1,2-propylene glycol and glycerol and low-concentration nicotine in the electronic cigarette smoke can be simultaneously analyzed; the internal diameter of the chromatographic column is 0.32 mm; feed detection of the high-concentration 1,2-propylene glycol and glycerol in the extracted solution is not overloaded; meanwhile the chromatographic peak tailing phenomenon of the 1,2-propylene glycol and glycerol with high polarity can be effectively improved by using the 1.8 mum thick liquid membrane column, so the quantification is more accurate.

Description

technical field [0001] The invention relates to a simultaneous determination method for 1,2-propanediol, glycerol and nicotine in electronic cigarette smoke, and belongs to the field of tobacco chemistry. Background technique [0002] E-cigarette is a product that atomizes the e-cigarette solution through an atomizer to deliver nicotine and / or other substances to the respiratory system. By simulating the smoking of traditional e-cigarettes, it brings smokers the same physical, psychological and smoking behavior satisfaction as smoking traditional e-cigarettes. The substances contained in e-cigarette liquid mainly include nicotine / tobacco extract, solvent and flavor and fragrance. Usually, 1,2-propanediol and glycerin as e-liquid solvents account for about 90% of e-liquid, and nicotine in e-liquid is usually in the concentration range of 0-36 mg / mL, which accounts for only 3% of e-liquid. %about. The main components in e-cigarette smoke include nicotine, propylene glycol, ...

AI Technical Summary

Problems solved by technology

[0003] At present, there are very few domestic studies on the analysis of e-cigarette smoke components, only the analysis of nicotine, no analysis methods for 1,2-propanediol and glycerol in e-cigarette The release amount of the main components of the smoke is not completely clear

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