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A kind of mixed gum chewable soft capsule and preparation method thereof

A soft capsule and mixed glue technology, which is used in capsule transportation, pharmaceutical formulations, food forming and other directions, can solve problems such as chewability, temperature resistance, stability, shelf life time limit, and small addition amount. The effect of good flavor release, reducing deformation and prolonging shelf life

Inactive Publication Date: 2017-12-05
GUANGZHOU ZHAIJIA COMMODITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, there is also gellan gum and gelatin compounded as the gum base to prepare the capsule skin of the soft capsule, but gelatin accounts for a large proportion in the formula, and the amount of gellan gum added is usually used as an auxiliary material, and the amount added is very small. It is small and mostly plays the role of thickener in the formula. Therefore, the prepared soft capsules still cannot completely solve their deficiencies in chewability, temperature resistance, stability, and shelf life.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Example 1 The mixed gum chewing soft capsule of the present invention was prepared according to the following steps:

[0026] (1) Take the raw material components with the following mass ratios: gellan gum: dextrin: gelatin (animal gelatin of 150 Bloom): glycerin: thickener (xanthan gum): deionized water: flavoring agent (crystalline fructose) )=25:12:10:25:8:8:12; take linseed oil as the contents of the capsule;

[0027] (2) Set the temperature of the gelatinizer tank to 65℃ to heat the gelatinizer tank, add glycerin, 70% deionized water, dextrin, 30% crystalline fructose, and stir at a speed of 50 rpm until the raw materials in the gelatinizer tank are dissolved and mixed. uniform;

[0028] (3) When the temperature of the material in the glue tank reaches 90℃, add gellan gum, stir at 50 rpm for 0.5~1h to dissolve the gellan gum evenly, and then add the remaining flavoring agent, thickener and remaining Deionized water, and continue to stir for 1 hour until the raw material...

Embodiment 2

[0031] Example 2 The mixed gum chewing soft capsule of the present invention was prepared according to the following steps:

[0032] (1) Take the raw material components with the following mass ratios: gellan gum: dextrin: gelatin (animal gelatin with a jelly force of 250 Bloom): glycerin: thickener (linseed gum): deionized water: flavoring agent (trichloro Sucrose)=20:10:10:30:4:16:10; take sea buckthorn oil as the contents of the capsule;

[0033] (2) Set the temperature of the gelatinizer tank to 70℃, heat the gelatinizer tank, add glycerin, 70% deionized water, dextrin, 30% sucralose, and stir at 60 rpm until the raw materials are dissolved in the gelatinizer tank Mix well

[0034] (3) When the temperature of the material in the gel tank reaches 85°C, add gellan gum, stir at 60 rpm for 0.5~1h to dissolve the gellan gum evenly, and then add the remaining flavoring agent, thickener and remaining Deionized water, and continue to stir for 2h until the raw materials are dissolved in...

Embodiment 3

[0037] Example 3 The mixed gum chewing soft capsule of the present invention was prepared according to the following steps:

[0038] (1) Take the raw material components with the following mass ratios: gellan gum: dextrin: gelatin (80 Bloom animal gelatin): glycerin: thickener (seedale gum): deionized water: flavoring agent (crystalline fructose) )=26:15:5:15:10:14:15; take linseed oil as the contents of the capsule;

[0039] (2) Set the temperature of the gelatinizer to 75℃ to heat the gelatinizer, add glycerin, 70% deionized water, dextrin, 30% crystalline fructose, and stir at 70 rpm until the raw materials in the gelatinizer are dissolved and mixed. uniform;

[0040] (3) When the temperature of the material in the glue tank reaches 80℃, add gellan gum, stir at 70 rpm for 0.5~1h to dissolve the gellan gum uniformly, and then add the remaining flavoring agent, thickener and remaining Deionized water, and continue to stir for 0.5h until the raw materials are dissolved in the glue ...

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PUM

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Abstract

The invention discloses a mixed gum chewing type soft capsule and a preparation method thereof. The capsule skin of the soft capsule is prepared from the following raw materials in percentage by mass: 20-40% of gellan gum, 10-15% of dextrin, 5-15% of gelatin, 15-30% of glycerol, 4-10% of a thickening agent, 10-20% of deionized water and 10-15% of a flavoring agent; and the content of the capsule is liquid or a semisolid medicament, a health food or a food. The capsule skin of the capsule disclosed by the invention takes a mixed gum consisting of the gellan gum, the gelatin and the dextrin as a gum base, wherein the gellan gum is the main component and is compounded with the gelatin to obtain the gum base, the gelling performance of the gum base has a synergistic effect, and the dextrin is beneficial for forming a gel with a stable structure; and the thickening agent is used for controlling syneresis and reducing the brittleness of the gum base, and the flavoring agent is used for increasing the mouthfeel and good smell while solving a hydration problem of the gellan gum. The mixed gum chewing type soft capsule is good in temperature resistance, suitable in capsule skin strength, thickness and toughness, and good in chewing property and mouthfeel, is difficult to deform and generate adhesion and oil leakage, and is high in stability and convenient to store and transport, and the product shelf life is prolonged.

Description

Technical field [0001] The present invention relates to a soft capsule, specifically a mixed gum chewable soft capsule and a preparation method thereof, and belongs to the technical field of pharmaceuticals, food, health food or preparations. Background technique [0002] Chewable soft capsules are chewable soft capsules. Compared with traditional capsule preparations, chewable soft capsules have good chewiness and are easy to take. They are popular among the elderly, children and patients who have difficulty swallowing traditional soft capsules. However, the existing chewable soft capsules have poor chewiness, insufficient temperature resistance, are prone to capsule deformation, adhesion and oil leakage, are not very stable, and have a short shelf life. [0003] Patents US6280767, WO2011014942, and ZL00806658.2 respectively disclose chewable soft capsules with animal glue as the base. They increase the amount of plasticizer in the rubber or maintain a high moisture content...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K47/36A61J3/07A23L33/00A23P10/00
Inventor 陈文俊
Owner GUANGZHOU ZHAIJIA COMMODITY
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