Method for preparing pinoresinol from salted turnips

Abstract

The invention discloses a method for preparing pinoresinol from salted turnips, which comprises the following steps: 1, the preparation of dry salted-turnip powder: slicing salted turnips, drying at a temperature of 50 DEG C, crushing, sieving by using a 20-mesh sieve so as to obtain dry salted-turnip powder, putting the dry salted-turnip powder into a sealed bag, and putting the sealed bag into a dryer for standby application; 2, the preparation of a salted-turnip crude extract; 3, the preliminary separation of the salted-turnip crude extract; 4, the separation and purification of a component Y1; and 5, the separation and purification of components 1-2: after a moderate amount of alcohol is added into the components 1-2 for dissolving, enabling the obtained object to pass through a reverse-phase silica gel column to carry out separation, eluting by using 50% CH3OH, and selecting a fourth flow component and separating by using a normal phase silica gel; eluting by using petroleum ether, collecting flow components of 97th to 116th pipes, merging the flow components, concentrating the obtained object, and removing a solvent by evaporating, so that pinoresinol is obtained. According to the invention, pinoresinol is separated from salted turnips for the first time, and as a main antifungal ingredient of the salted turnips, the pinoresinol is of great significance for the secondary development of salted turnips.

Description

technical field [0001] The invention relates to the technical field of active medicines, in particular to a method for preparing pinoresin from salted radish. Background technique [0002] Pinoresin is a class of lignans found in the medicinal plant pandanus, which is commonly used to treat thyroid disease and fever, and the anti-inflammatory forsythia plant. Pinoresin has good antifungal activity, can destroy the plasmid membrane of fungi without causing hemolysis of human erythrocytes and play an antibacterial effect, and is a potential antibacterial agent for treating human fungal infections. Among many lignan compounds, pinoresin can exhibit the strongest inflammatory activity after being absorbed and metabolized in the small intestine. In addition, pinoresin can also prevent cardiovascular diseases such as atherosclerosis by inhibiting the oxidation of low-density lipoprotein. [0003] Milder et al. have investigated the content of four lignans including pinoresin in ...

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Problems solved by technology

Landet et al. summarized pinoresin from plants and mammals and found that, in addition to vegetables, some oil seeds such as sesame seeds, sunflower seeds, etc., grains such as rye, wheat, oats and corn, etc., fruits such as apricots and mangosteen , strawberry, grapefruit, red dates, etc., alcoholic beverages such as beer, white wine, red wine, etc., and non-alcoholic beverages such as black tea, green tea, soybean milk, etc., all have different amounts of pinoresin, but there are few reports of pinoresin in radish and its pickled products. the existence of prime

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