Lysozyme oral care health-care fluid and preparation method thereof

A technology of oral care and lysozyme, which is applied in the directions of oral care, antibacterial drugs, and pharmaceutical formulations, can solve problems affecting the taste of products, high alcohol content, fluorosis, etc., and improve oral health problems. The production and preparation methods are simple, Good effect on gingivitis

Active Publication Date: 2015-10-21
HUBEI SHENDI AGRI SCI & TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005]Oral care solutions are commonly used as oral sprays and mouthwash products. Oral care solutions sold on the market usually use antibiotics and bacteriostats, which are easy to cause bacteria to produce Side effects such as drug resistance or oral discomfort, such as: Chinese patent CN 101829027 B and Chinese patent CN 101999990 B both use fluoride as a bacteriostatic agent, but now many products including toothpaste contain fluoride, and long-term use is easy to cause Fluorine exceeds the standard. Studies have shown that excessive use of fluoride can cause fluorosis and a series of diseases. It is especially not recommended for pregnant women and children under the age of 7 to use fluorine-containing products
[0006] At the same time, most of the oral care solutions sold on the market contain alcohol, which can irritate the oral mucosa, which is inconvenient for patients with oral diseases, and can also cause harm to drivers and alcohol allergies. Inconvenient, such as: Chinese patent CN 101249056 B, although active ingredients such as Luo Han Guo extract and vitamin B12 are added, but due to the solubility and stability of the formula, the alcohol content is as high as 20%
[0007]In addition, there are many oral sprays and mouthwash products of Chinese herbal medicines on the market, but Chinese herbal medicines often taste bitter and have a strong color, which greatly affects the taste and appearance of the products. For example: Chinese patent CN 101627965 B uses at least two kinds of magnolia officinalis, tea polyphenols, and propolis as active ingredients, all of which are bitter ingredients, which seriously affect the taste of the product

Method used

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  • Lysozyme oral care health-care fluid and preparation method thereof
  • Lysozyme oral care health-care fluid and preparation method thereof
  • Lysozyme oral care health-care fluid and preparation method thereof

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Embodiment Construction

[0033] Embodiments of the present invention are described in detail below, but are not limited to the following embodiments:

[0034] A lysozyme oral care and health care liquid is provided, which is prepared according to the weight percentage of each component disclosed in the above-mentioned technical scheme and according to its preparation steps; the description will not be repeated.

[0035] Below, the screening and the source of each component of the present invention are further described; To prove its embodiment:

[0036] (1) Optimum dosage of active ingredient lysozyme

[0037] The optimal dosage of lysozyme was determined by the zone of inhibition method. Use the agar diffusion method to incubate the sterilized TSA medium in the air for 24 hours, take 0.2mL of the isolated and identified Staphylococcus aureus (Candida albicans) suspension on the plate, spread it evenly with a sterile glass handle, and apply After cloth, the plate shall be subject to no visible water...

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Abstract

The invention discloses lysozyme oral care health-care fluid and a preparation method thereof. The lysozyme oral care health-care fluid comprises 0.001-10% of lysozyme, 0.01-10% of tea polyphenol, 0.001-0.1 ppm of vitamin B12, 0.1-10% of freshener, 1-20% of sweetening agents, 0.1-6% of solubilizing agents, 0.01-0.6% of scented water and 43.4-98.77% of purified water. The 0.01-10% of lysozyme, 0.01-10% of tea polyphenol and 1-20% of sweetening agents are sequentially dissolved in a stainless steel container according to a proportion, slightly stirred and sufficiently and evenly mixed, so that fluid A is obtained through preparation; the 0.1-10% of freshener and 0.01-0.6% of scented water are sequentially dissolved in the 0.1-6% of solubilizing agents according to a proportion, slightly stirred and sufficiently and evenly mixed, so that fluid B is obtained through preparation. The fluid B is slowly poured into the fluid A and stirred slightly, and the 0.001-0.1 ppm of vitamin B12 is added and sufficiently and evenly mixed. The evenly mixed material is filtered, packaged and subjected to filling, so that the health-care fluid is obtained. The lysozyme oral care health-care fluid is obvious in effect, main functional components are natural extracts and do not contain alcohol, and the lysozyme oral care health-care fluid is mild in taste and capable of effectively improving the micro-ecological environment of the oral cavity without stimulating the oral mucosa while meeting the requirements for cleaning the oral cavity and freshening breath.

Description

technical field [0001] The invention relates to the technical field of oral health products for killing harmful bacteria in the oral cavity and preventing oral problems, in particular to lysozyme oral care health care liquid and a preparation method thereof. Background technique [0002] The oral cavity is an important part of the digestive and respiratory systems of the human body. With the aggravation of air pollution and environmental deterioration, oral diseases are showing an obvious upward trend. Common oral diseases include oral ulcers, dental caries, periodontitis, gingivitis, etc. The important causes of oral diseases are incomplete oral cleaning and food residues remaining in the oral cavity. [0003] In daily life, people are used to brushing their teeth once in the morning and evening to clean the mouth, but it is difficult to ensure that the residues in the mouth are completely removed by brushing teeth. For example, it is difficult for children to clean the mou...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/66A61K8/67A61K8/92A61Q11/00A61P1/02A61P31/04
Inventor 张宇左思敏朱玲娇李垚曾龙虎
Owner HUBEI SHENDI AGRI SCI & TECH CO LTD
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