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Antibacterial gel hand cleanser and preparation method thereof

A technology of hand sanitizer and gel, which is applied in the direction of local antibacterial agents, pharmaceutical formulas, cosmetic preparations, etc., can solve the problems of high initial investment cost and limited wide application, and achieve low cost, simple preparation process equipment, and easy application Effect

Inactive Publication Date: 2015-11-25
SOUTH CHINA UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, because the foam preparation needs to use special supporting facilities, the initial investment cost is slightly higher, which limits its wide application in hospitals.

Method used

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  • Antibacterial gel hand cleanser and preparation method thereof
  • Antibacterial gel hand cleanser and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] An antibacterial gel hand wash, its raw material formula is as follows: tea tree oil 2g, chlorhexidine acetate 5g, polyethylene glycol 1000 vitamin E succinate 10mg, ethanol 15g, glycerin 3g, petrolatum 1g, stearic acid 0.2g, Olive oil 0.5g, coconut oil 0.2g, castor oil 0.5g, lanolin alcohol 0.2g, lecithin 0.5g, lanolin acid 0.2g, Tween 80 0.5g, glyceryl stearate 0.5g, PEG-20 dehydration 0.5g of pitol isostearate, 2g of carbomer 940, 1g of triethanolamine, 0.3g of citric acid, 0.5g of tartaric acid, and the rest are deionized water to prepare 100g of antibacterial gel hand sanitizer.

[0034] During preparation, add tea tree oil, chlorhexidine acetate, glycerin, petrolatum, stearic acid, olive oil, coconut oil, castor oil, lanolin alcohol, lecithin and lanolin acid into ethanol, dissolve at 70°C to make Alcohol solution; Tween 80, glyceryl stearate, PEG-20 sorbitan isostearate and polyethylene glycol 1000 vitamin E succinate were added to 16.39g deionized water to form ...

Embodiment 2

[0036] An antibacterial gel hand wash, its raw material formula is as follows: tea tree oil 4g, chlorhexidine acetate 5g, macrogol 1000 vitamin E succinate 100mg, isopropyl alcohol 18g, polysiloxane 2g, cetyl alcohol 1g, vaseline 1g, lecithin 0.5g, sesame oil 0.5g, almond oil 0.2g, peanut oil 0.2g, corn oil 0.2g, rice bran oil 0.5g, tea seed oil 0.5g, seabuckthorn oil 0.2g, avocado oil 0.2g, Chestnut oil 0.2g, Tween 80 0.5g, macrogol glyceride 0.5g, glyceryl stearate 0.2g, carbomer 940 2g, triethanolamine 1g, glutaric acid 0.5g, maleic acid 0.5g , glutamic acid 0.2g, and the rest is deionized water, which is prepared into 100g antibacterial gel hand sanitizer.

[0037] For preparation, tea tree oil, chlorhexidine acetate, polysiloxane, cetyl alcohol, petrolatum, lecithin, sesame oil, almond oil, peanut oil, corn oil, rice bran oil, tea seed oil, sea buckthorn oil, avocado oil Add Heshi chestnut oil to isopropanol and dissolve it at 40°C to make an alcohol solution; add Tween ...

Embodiment 3

[0039]An antibacterial gel hand wash, its raw material formula is as follows: tea tree oil 4g, chlorhexidine acetate 2.5g, polyethylene glycol 1000 vitamin E succinate 50mg, ethanol 12g, glycerin 2g, hexadecanol 1g, polysilicon Oxane 0.2g, Rice Bran Oil 1g, Tea Seed Oil 2g, Seabuckthorn Oil 0.5g, Avocado Oil 0.5g, Stone Chestnut Oil 0.5g, European Argan Oil 0.2g, Lecithin 0.2g, Tween 80 0.5g, Glycerin Hard Fatty acid ester 0.2g, PEG-20 sorbitan isostearate 0.2g, carbomer 940 2g, triethanolamine 1g, malic acid 0.5g, succinic acid 0.2g, maleic acid 0.1g, the rest is Ionized water, formulated into 100g antibacterial gel hand sanitizer.

[0040] For preparation, tea tree oil, chlorhexidine acetate, glycerin, cetyl alcohol, polysiloxane, rice bran oil, tea seed oil, sea buckthorn oil, avocado oil, stone chestnut oil, argan oil, and lecithin are added to ethanol , dissolved at 70°C to make an alcohol solution; add Tween 80, glyceryl stearate, PEG-20 sorbitan isostearate and polyeth...

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Abstract

The invention discloses antibacterial gel hand cleanser and a preparation method thereof. The preparation method comprises the following steps of adding tea tree oil, chlorhexidine acetate and skin care agents in alcohol substances and dissolving at the temperature of 30-70 DEG C to form alcohol solution; adding surfactant and water soluble vitamin E derivative in deionized water to form aqueous solution; adding carbomer in the deionized water; stirring and standing until the carbomer swells sufficiently and disperses uniformly to form semi-solid gel; mixing the aqueous solution and alcohol solution and slowly adding the mixture in the semi-solid gel; adding pH (potential of hydrogen) regulating agents until the pH value is 6.8-7.4; and stirring for 10-30 minutes by using a high-speed homogenizer under the condition that the rotating speed is 1000-5000rmp to obtain the antibacterial gel hand cleanser. The antibacterial gel hand cleanser contains various antibiotic constituents, has rapid and durable effects, is low in irritation and stability, has good broad-spectrum bactericidal and antibacterial effects, and also has good moisturizing and anti-oxidation effects.

Description

technical field [0001] The invention relates to the field of medical antibacterial hand sanitizer, in particular to an antibacterial gel hand sanitizer which reduces bacterial species such as Escherichia coli, Staphylococcus aureus and Candida albicans on hands and has a long-lasting antibacterial effect and a preparation method thereof. Background technique [0002] Among the chemical disinfectants used in hospitals, benzalkonium bromide was mainly used in the 1970s, peracetic acid was mainly used in the 1980s, and chlorine-containing disinfectants were mainly used in the 1990s. Benzalkonium bromide is a low-efficiency disinfectant that kills limited types of microorganisms; peracetic acid is a high-efficiency disinfectant, but it is too corrosive and unstable; chlorine-containing disinfectants have reliable disinfection effects, but have a strong pungent odor. At present, the hand-washing disinfectants used in hospitals of various levels and types circulated in the domesti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/92A61K8/67A61Q19/10A61Q19/00A61P31/02
Inventor 魏坤胡露
Owner SOUTH CHINA UNIV OF TECH
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