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Traditional Chinese medicine composition for treating viral myocarditis and preparation method thereof

A technology for viral myocarditis and composition, applied in the field of traditional Chinese medicine composition for the treatment of viral myocarditis and its preparation field, can solve the problems of unsatisfactory clinical effect, large toxic and side effects of western medicine, limited effect of medication guidance and the like

Inactive Publication Date: 2015-12-02
QINGDAO JINZHI HIGH NEW TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the research on the therapeutic mechanism of some single traditional Chinese medicines, such as Astragalus, Sophora flavescens, etc., is relatively in-depth, and these single medicines have been sold in the market, their clinical effects are not satisfactory
In addition, the mortality rate of animal models is relatively high, and its manifestations tend to be Shaoyin disease, Yang Qi deficiency syndrome, and clinical symptoms such as Qi deficiency, blood stasis, etc., there is a certain gap
Moreover, the specificity of experimental medication symptoms is not yet strong, and the role of clinical medication guidance is limited.
[0008] The purpose of the present invention is to overcome the existing western medicines for viral myocarditis with large toxic and side effects, unsustainable therapeutic effects, and unsatisfactory therapeutic effects of traditional Chinese medicine. It has the advantages of strong pertinence, good curative effect, short cycle, low price, no toxic and side effects, etc., and can make patients willing to accept it, and can be a pure Chinese medicine preparation for the treatment of viral myocarditis.

Method used

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  • Traditional Chinese medicine composition for treating viral myocarditis and preparation method thereof
  • Traditional Chinese medicine composition for treating viral myocarditis and preparation method thereof

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preparation example Construction

[0042] The present invention also provides a preparation method of the above-mentioned traditional Chinese medicine composition, comprising:

[0043] Mix the components in the raw material components in proportion, pulverize them, soak them in 5-8 times the amount of water for 12-24 hours, extract the volatile oil by steam distillation, save the distilled medicinal residues and medicinal liquid separately, and reduce the medicinal liquid Press recovery and concentrate until the relative density is 1.07-1.13 at 75-85°C to obtain A; add 65% ethanol to dissolve the above-mentioned volatile oil at a ratio of 1:1, and use colloidal milling method to make the ratio of volatile oil and β-cyclodextrin 1:7 -9, The ratio of β-cyclodextrin to water is 1:1-3, adopt appropriate grinding speed to grind for 15-30 minutes for clathrate, obtain paste, dry at 40-60°C, and pulverize to obtain clathrate B; the above dregs continue to be reflux extracted with 65-85% ethanol for 1-3 times, 5-10 tim...

Embodiment 1

[0048] Take 10 parts by weight of Sophora japonica, 8 parts by weight of Schisandra chinensis, 6 parts by weight of notopterygium, 8 parts by weight of rehmannia glutinosa, 5 parts by weight of epimedium, 10 parts by weight of honeysuckle, 9 parts by weight of cassia twig, 6 parts by weight of hawthorn, and 5 parts by weight of longan meat 6 parts by weight of Cassia Spatholobus, 8 parts by weight of Cassia Semen, 8 parts by weight of Ophiopogon japonicus, 10 parts by weight of Ligustrum lucidum, 6 parts by weight of Angelica sinensis, 5 parts by weight of Rhizoma Chuanxiong, mixed in proportion, pulverized; hours, extract the volatile oil by steam distillation, save the distilled medicinal residues and medicinal liquid, recover and concentrate the medicinal liquid under reduced pressure until the relative density is 1.07 at 75°C to obtain A; the above-mentioned volatile oil is dissolved in 65% ethanol at a ratio of 1:1 Adopt the colloid milling method, take the ratio of volati...

Embodiment 2

[0052] Take 16 parts by weight of Sophora japonica, 14 parts by weight of Schisandra chinensis, 12 parts by weight of notopterygium, 15 parts by weight of rehmannia glutinosa, 10 parts by weight of epimedium, 16 parts by weight of honeysuckle, 18 parts by weight of cassia twig, 14 parts by weight of hawthorn, and 10 parts by weight of longan meat 12 parts by weight of Cassia Spatholobus, 18 parts by weight of Cassia Semen, 14 parts by weight of Ophiopogon japonicus, 16 parts by weight of Ligustrum lucidum, 12 parts by weight of Angelica sinensis, 10 parts by weight of Rhizoma Chuanxiong, mixed in proportion, pulverized; soaked in 8 times the amount of water for 24 hours, extract the volatile oil by steam distillation, save the distilled medicinal residues and medicinal liquid, recover and concentrate the medicinal liquid under reduced pressure until the relative density is 1.13 at 85°C to obtain A; the above-mentioned volatile oil is dissolved by adding 65% ethanol in a ratio of...

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Abstract

The invention provides a traditional Chinese medicine composition for treating viral myocarditis. The traditional Chinese medicine composition comprises sophora flower, Chinese magnoliavine fruit, notopterygium root, prepared rehmannia root, epimedium herb, honeysuckle, cassia twig, hawthorn, longan pulp, suberect spatholobus stem, cassia seed, radix ophiopogonis, fructus ligustri lucidi, angelica sinensis and rhizoma chuanxiong. Compared with pure western medicine treatment, the traditional Chinese medicine composition has the advantages that viral myocarditis index can be well lowered, the clinical signs of a patient can be improved, further deterioration of the viral myocarditis can be prevented, and meanwhile, the traditional Chinese medicine composition is free of toxic and side effects and high in safety and comfortableness.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating viral myocarditis and a preparation method thereof. Background technique [0002] Viral myocarditis (VMC) is a common and frequently-occurring disease of the cardiovascular system, and it is also one of the main causes of dilated cardiomyopathy, heart failure and sudden death. At present, whether in developed countries or in developing countries, the incidence of myocarditis has increased significantly compared with 10 years ago. The main reason is that the incidence of viral myocarditis in infectious myocarditis has increased. After viral infection invades the myocardium, it will cause focal or diffuse myocardial interstitial exudation and myocardial fibrosis and necrosis. Severe diffuse myocarditis may lead to severe arrhythmia, heart failure, cardiogenic shock, and even sudden death; it may also pers...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P31/12A61P9/00
Inventor 不公告发明人
Owner QINGDAO JINZHI HIGH NEW TECH
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