Traditional Chinese medicine for treating chemotherapeutic phlebitis of tumor patients and preparation method thereof

A technique for patients with chemotherapy-induced phlebitis and tumors, which is applied in the direction of medical formulas, medical preparations containing active ingredients, and drug combinations, etc. simple effect

Inactive Publication Date: 2016-01-27
战士娟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the commonly used treatment methods include cold compress, drug sealing, local physical therapy, local drug wet compress or external application, etc. Although they have a certain therapeutic effect, the curative effect is still not ideal.

Method used

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Effect test

preparation example Construction

[0042] The present invention further provides a preparation method of the above-mentioned Chinese medicine for treating tumor patients with chemotherapeutic phlebitis, the dosage form of the Chinese medicine is granule, and the preparation method comprises the following steps:

[0043] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 85% to 95% relative to the mixture 4 to 8 times, heat to boiling and reflux for 3 to 5 hours, filter, and use the reflux liquid as a solvent , using the filter residue as the solute, use the percolation method to slowly percolate at a rate of 1-2ml per minute, collect the percolation liquid, and then concentrate it under reduced pressure at a vacuum of 0.06-0.09Mpa to 50-60°C with a relative density of 1.04 ~1.10 paste, spray drying, the air inlet temperature of the spray dryer is 160~175℃, and the air outlet temperature is 80~85℃, and then crushed into powder to make dry paste powd...

Embodiment 1

[0050] Embodiment 1: Granules

[0051] Take 160g of Agrimony, 240g of winter jasmine leaves, 100g of wooden steamed buns, 220g of red leaf trees, 140g of silver orchids, 220g of Tibetan green fruits, 250g of geraniums, 260g of dragon grass, 100g of money grass, 280g of flower trees, 200g of rowans, and bars 260g Gui, 160g Iris, 240g Yexiang Beef, 160g Purple Back Vegetable and 280g Single Flower Orchid;

[0052] Its preparation method comprises the following steps:

[0053] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration 6 times that of the mixture and 95% ethanol, heat to boiling and reflux for 3 hours, filter, use the reflux liquid as the solvent, and use the filter residue as the solute. The percolation method slowly percolates at a speed of 2ml per minute, collects the percolation liquid, and then concentrates it under reduced pressure at a vacuum of 0.08Mpa to a paste with a relative density of 1.05 at 55°C...

Embodiment 2

[0055] Embodiment 2: tablet

[0056] Take 180g of Agrimony, 220g of winter jasmine leaves, 120g of wooden steamed bread, 180g of red leaf tree, 170g of silver orchid, 200g of Tibetan green fruit, 280g of geranium, 240g of dragon grass, 140g of money grass, 240g of flower tree, 220g of rowan, and bar plate 240g Gui, 140g Iris, 200g Yexiang Beef, 180g Purple Back Vegetable and 260g Single Flower Orchid;

[0057] Its preparation method comprises the following steps:

[0058] The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 85% that is 4 times the mass of the mixture, heat and reflux for 2 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 95% relative to the quality of the dregs, heat and reflux for 1.5 hours, extract, and filter to obtain the second extract; combine the first extract and the second extract, an...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for treating chemotherapeutic phlebitis of tumor patients and a preparation method thereof. The traditional Chinese medicine is prepared from the following medicinal raw materials: agrimonia pilosa ledeb, leaves of jasminum nudiflorum, ficus pumila linn, helicia cochinchinensis, cephalanthera erecta, terminalia chebula retz, geranium wilfordii maxim, senecio jacobacea, lysimachia chiristinae hance, stemof falsetomentoseanther clematis, sorbus pohuashanensis, perfoliote knotweed herb, sweet iris flower, vernonia cinerea, gynura bicolor and changnienia amoena. The traditional Chinese medicine has the beneficial effects of safe use, no toxic or side effect, no allergic reaction, high efficiency and quick response, and can be used for quickly eliminating local heat and pain of a patient in 1-2 days and quickly eliminating red, swelling and the like of the patient in 2-3 days. The preparation process is simple.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine engineering, in particular to a traditional Chinese medicine for treating tumor patients with chemotherapeutic phlebitis and a preparation method thereof. Background technique [0002] Intravenous chemotherapy is one of the important means of treating malignant tumors. Since most chemotherapeutic drugs are chemical or alkaloid preparations with high toxicity and high concentration, the mechanical stimulation caused by repeated, multiple, and high-dose intravenous pulse chemotherapy and the local strong stimulation of high-concentration drugs can lead to pain in the administration vein and adjacent tissues. Redness, swelling, pain, arteriosclerosis, etc., cause phlebitis. Varying degrees of phlebitis can occur in 50%-80% of chemotherapy patients. Chemotherapy-induced phlebitis is a common type of phlebitis, and it is one of the side effects during chemotherapy. It is caused b...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61P9/14
Inventor 战士娟李留娟
Owner 战士娟
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