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A kind of preparation method of Ejiao Yishou oral liquid

A technology for oral liquid and donkey-hide gelatin, which is applied in the field of preparation of donkey-hide gelatin oral liquid, can solve the problems of high viscosity of extract, decrease of drug efficacy, adhesion of extract, etc., so as to reduce viscosity, improve utilization rate, and reduce the amount of adhesion Effect

Active Publication Date: 2018-08-28
SICHUAN XUYANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, usually the water extract is directly concentrated, because the sugars and cellulose substances in the crude drug enter the extract, the viscosity of the extract is relatively high after concentration, causing the extract to adhere to the wall of the extraction tank without easy to get
Moreover, in the process of refining the extract, the use of pure water for dissolving often causes part of the extract to be incompletely dissolved or has low solubility, causing some effective substances to be filtered out along with the residue, thereby reducing the efficacy

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] The prescription of Ejiao Yishou Oral Liquid is:

[0030] Ginseng 30.48kg, Honey-made Astragalus 304.8kg, Rehmannia glutinosa 152.4kg, Polygonum multiflorum 152.4kg;

[0031] Ejiao 76.2kg, tangerine peel 60.96kg, woody fragrance 30.48kg, licorice 30.48kg,

[0032] Sucrose 120kg, sodium benzoate 6kg.

[0033] Preparation steps:

[0034] Extraction: put ginseng, dried tangerine peel, licorice, woody incense, sunburned astragalus, rehmannia glutinosa, and Polygonum multiflorum into a multi-functional extraction tank according to the principle of equal parts, add 6 times the total amount of medicinal materials for the first time and boil for 120 minutes. Add pure water 5 times the total amount of medicinal materials for the second time, boil for 120 minutes, add pure water 5 times the total amount of medicinal materials for the third time, and boil for 60 minutes. The steam pressure of the heating control jacket is 0.20Mpa; the micro-boiling temperature is controlled at ...

Embodiment 2

[0048] The prescription of Ejiao Yishou Oral Liquid is:

[0049] Ginseng 30.48kg, Honey-made Astragalus 304.8kg, Rehmannia glutinosa 152.4kg, Polygonum multiflorum 152.4kg;

[0050] Ejiao 76.2kg, tangerine peel 60.96kg, woody fragrance 30.48kg, licorice 30.48kg,

[0051] Sucrose 120kg, sodium benzoate 6kg.

[0052] Preparation steps:

[0053] Extraction: put ginseng, dried tangerine peel, licorice, woody incense, sunburned astragalus, rehmannia glutinosa, and Polygonum multiflorum into a multi-functional extraction tank according to the principle of equal parts and equal parts. Add 6 times the total amount of medicinal materials for the first time and boil for 120 minutes. Add 5 times pure water of the total amount of medicinal materials for the second time, boil for 120 minutes, add 5 times pure water of the total amount of medicinal materials for the third time, and boil for 60 minutes. The steam pressure of the heating control jacket is 0.20Mpa; the micro-boiling tempera...

Embodiment 3

[0057] The prescription of Ejiao Yishou Oral Liquid is:

[0058] Ginseng 30.48kg, Honey-made Astragalus 304.8kg, Rehmannia glutinosa 152.4kg, Polygonum multiflorum 152.4kg;

[0059] Ejiao 76.2kg, tangerine peel 60.96kg, woody fragrance 30.48kg, licorice 30.48kg,

[0060] Sucrose 120kg, sodium benzoate 6kg.

[0061] Preparation steps:

[0062] Extraction: Put ginseng, tangerine peel, licorice, woody fragrance, sun-roasted astragalus, rehmannia glutinosa, and Polygonum multiflorum into the multi-functional extraction tank according to the principle of equal parts. 6% ethanol and 1% potassium sorbate were boiled for 120min, and the pH was controlled to be 6.8. For the second time, 5 times the total amount of medicinal materials was added in pure water, 7% ethanol and 1.5% potassium sorbate, and boiled for 120min. 5 times the total amount of medicinal materials, pure water, 8% ethanol and 2% potassium sorbate were added three times, and boiled for 60 minutes. 25,000 Hz ultraso...

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Abstract

The invention discloses a preparation method of a donkey-hide gelatin oral solution with a function of life prolongation. The preparation method comprises repeated boiling extraction of seven crude drugs, an extracting solution is concentrated through a triple-effect concentrator, a double-effect concentrator and a single-effect concentrator respectively, concentrated extract is refined in pure water, a donkey-hide gelatin solution and syrup are prepared, and material preparation is completed. According to the method, the water extracting solution is divided into three parts and sequentially concentrated through the triple-effect concentrator, the double-effect concentrator and the single-effect concentrator respectively, and the viscosity of the concentrated extract is reduced through sectional concentration of the extracting solution. Meanwhile, the water precipitation step of the extract is further optimized, so that effective ingredients in the extract are better dissolved in and dissolved out of water, and the utilization rate of the effective ingredients is increased.

Description

technical field [0001] The invention relates to the technical field of extraction and preparation of traditional Chinese medicines, in particular to a preparation method of donkey-hide gelatin Yishou oral liquid. Background technique [0002] Donkey-hide gelatin Yishou Oral Liquid nourishes qi and nourishes blood. It is used for deficiency of qi and blood, weakness of limbs, soreness of waist and knees, sallow complexion, forgetfulness and insomnia, and postpartum women with various deficiencies. Women's postpartum deficiency is a relatively common and frequently occurring disease in clinical practice, which seriously affects people's daily life; there are many Chinese patent medicines for treating this disease at present, but these varieties all have defects such as unsatisfactory curative effects. Existing technology: Ejiao Yishou Oral Liquid under the item WS3-B-1143-92 in the sixth volume of "Prescriptions of Traditional Chinese Medicine" issued by the Ministry is a pure...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/08A61K36/804A61P1/14A61P39/00A61K35/36
CPCA61K9/0053A61K9/08A61K35/36A61K36/258A61K36/285A61K36/481A61K36/484A61K36/704A61K36/752A61K36/804A61K47/26A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 韩业祥侯嘉
Owner SICHUAN XUYANG PHARMA