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Composite hydrogel contact lens material preparation method

A technology of hydrogel contact lenses and raw materials, applied in glasses/goggles, instruments, optics, etc., can solve the problem of poor mechanical properties of light transmittance lenses, inability to help eyes relieve fatigue, low health care and medicinal value, etc. problems, to achieve the effect of high health care and medicinal value, low expansion rate and good mechanical properties

Inactive Publication Date: 2016-04-06
季叶俊
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Contact lenses, commonly known as "contact lenses", are made of colorless or dyed transparent materials based on the shape of the human cornea. When used, they are directly attached to the surface of the tear layer of the cornea and are physiologically compatible with the human eye. To achieve the purpose of vision correction, beauty treatment or treatment, the manufacturing materials of corneal contact lenses include hard air-tight materials, hard air-permeable materials, soft non-hydrophilic materials (also known as elastic materials) and soft hydrophilic materials , because the corneal contact lens made of hydrogel material has a short adaptation period and a strong sense of comfort, and the fitting technology is simpler than that of gas-permeable rigid lens. The hydrogel material is combined with ophthalmic drugs to manufacture a slow-release drug. Functional contact lenses have always been one of the goals that researchers are striving for, but the contact lens materials currently produced often only have the effect of simply correcting vision, and cannot help people's eyes relieve fatigue, and their health care and medicinal value are low. And the light transmittance and the mechanical properties of the lens are not very good

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] (1) Mixing of raw materials: first add cross-linked N-vinylpyrrolidone (NVP) particles into the porogen polyethylene glycol 400 and soak for 2-4 minutes, and then mix with the dissolved quantitative initiator dibenzoyl peroxide Mix HEMA with a glass rod for 1-3 minutes, pour it into a small plastic bag after mixing, put the plastic bag in hot water to fully drive out the gas, and seal the plastic bag after 1-2 minutes of hot water bath Standing up for use, wherein, the mass percentages of the crosslinked N-vinylpyrrolidone (NVP) particles, initiator, HEMA solution and porogen are 5.8%, 0.2%, 36% and 58% respectively;

[0017] (2) Heating reaction: Press the plastic bag sealed in step (1) into a glass mold, then put it into a water bath at 74°C for heating reaction, and control the reaction time to 10 hours;

[0018] (3) Removal of impurities: After the reaction in step (2) is complete, take out the polymer generated in the plastic bag, cut into thin slices, soak the thi...

Embodiment 2

[0020] Example 2: The rest are the same as in Example 1, except that in the step (1), the soaking time is controlled to be 3 minutes, the water bath time is controlled to be 1.5 minutes, and the cross-linked N-vinylpyrrolidone (NVP) particles, initiator, HEMA The mass percentages of the solution and the porogen are 6.7%, 0.3%, 41% and 52% respectively; in the step (2), the temperature of the water bath is controlled to be 76°C, and the reaction time is controlled to be 11h; in the step (3) , the soaking time is controlled to be 6 days; in the step (4), the drying temperature is controlled to be 79° C., and the drying time is controlled to be 19 hours.

Embodiment 3

[0021] Example 3: The rest are the same as in Example 1, except that in the step (1), the soaking time is controlled to be 4 minutes, the water bath time is controlled to be 2 minutes, and the cross-linked N-vinylpyrrolidone (NVP) particles, initiator, HEMA solution The mass percentages of porogen and porogen are 6.9%, 0.1%, 45% and 48% respectively; in the step (2), the temperature of the water bath is controlled to be 75°C, and the reaction time is controlled to be 12h; in the step (3), The soaking time is controlled to be 7 days; in the step (4), the drying temperature is controlled to be 80° C., and the drying time is controlled to be 20 hours.

[0022] After the above process steps, the lens material samples are taken out to be tested:

[0023] serial number Transmittance / % apparent strength Swelling rate / % Comfort Example 1 93.6 it is good 2.0 excellent Example 2 94.3 it is good 2.1 excellent Example 3 93.9 it is good ...

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PUM

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Abstract

The present invention discloses a composite hydrogel contact lens material preparation method, and relates to the technical field of glass production. The composite hydrogel contact lens material preparation method comprises four processes such as raw material mixing, heating reaction, impurity removal and drying. According to the present invention, in the process method, NVP particles having water absorbency of 7-8 are uniformly dispersed in a HEMA matrix phase having water absorbency of 1.6-1.7 by using a solution polymerization method to make the two materials form the composite structure hydrogel cornea contact lens material having the phase interface layer, and during the preparation process, the reaction temperature and the reaction time are controlled to make the two material be subjected to the complete reaction; and the lens material prepared through the preparation method has characteristics of high transparency, good mechanical property, low expansivity, high health value, and high medicinal value.

Description

technical field [0001] The invention relates to the technical field of eyeglass production, in particular to a preparation method of a composite hydrogel contact lens material. Background technique [0002] Contact lenses, commonly known as "contact lenses", are made of colorless or dyed transparent materials based on the shape of the human cornea. When used, they are directly attached to the surface of the tear layer of the cornea and are physiologically compatible with the human eye. To achieve the purpose of vision correction, beauty treatment or treatment, the manufacturing materials of corneal contact lenses include hard air-tight materials, hard air-permeable materials, soft non-hydrophilic materials (also known as elastic materials) and soft hydrophilic materials , because the corneal contact lens made of hydrogel material has a short adaptation period and a strong sense of comfort, and the fitting technology is simpler than that of gas-permeable rigid lens. The hydro...

Claims

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Application Information

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IPC IPC(8): C08F220/28C08F226/10C08J9/28G02C7/04G02B1/04
Inventor 季叶俊
Owner 季叶俊
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