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Lycopene composition with oxidation resistance and asthenopia relieving effects

A technology for relieving visual fatigue and lycopene, which is applied in food science, food shaping, and the function of food ingredients, etc. The effect of fatigue

Active Publication Date: 2016-05-25
JIANGSU SHENHUA PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] There are 11 conjugated double bonds and 2 non-conjugated double bonds in the lycopene molecule, which makes the stability of lycopene relatively poor. Under certain conditions, cis-trans isomerization and oxidative degradation can occur, resulting in lycopene The preparation is unstable, so the dosage form of lycopene on the market is generally soft capsules, but soft capsules require high technology and high cost

Method used

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  • Lycopene composition with oxidation resistance and asthenopia relieving effects
  • Lycopene composition with oxidation resistance and asthenopia relieving effects
  • Lycopene composition with oxidation resistance and asthenopia relieving effects

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0070] Main formula:

[0071] Lycopene oil 500g, lutein ester 100g, acerola cherry powder 100g, β-cyclodextrin 500g.

[0072] Preparation:

[0073] a. Dissolve β-cyclodextrin in distilled water at 50°C, keep the temperature constant for 30 minutes, add 1% emulsifier monoglyceride and lycopene oil (the ratio of core material to wall material is 1:1) by weight of lycopene oil, and homogenize , homogeneous condition temperature 50°C, pressure 30MPa, spray drying to obtain lycopene powder, spray drying conditions: inlet temperature 150°C, outlet temperature 75°C, flow rate 1500ml / h.

[0074] b. Mix lutein ester, acerola cherry powder and lycopene powder, and then mix them with maltodextrin and microcrystalline cellulose (the weight ratio of maltodextrin and microcrystalline cellulose is 1:1, and the dosage is lutein ester , Acerola powder and 1% of the total weight of lycopene powder), mixed evenly, and pressed into tablets to obtain the tablet weight 0.4g, 3000 tablets in total...

Embodiment 2

[0077] Main formula:

[0078] Lycopene oil 450g, lutein ester 100g, acerola cherry powder 100g, β-cyclodextrin 900g.

[0079] Preparation:

[0080] a. Dissolve β-cyclodextrin in distilled water at 80°C, keep the temperature for 30 minutes, add 0.5% emulsifier soybean lecithin and lycopene oil (the ratio of core material to wall material is 1:2), and homogenize. Homogeneous conditions temperature 30°C, pressure 40MPa, spray drying to obtain lycopene powder, spray drying conditions: inlet temperature 170°C, outlet temperature 85°C, flow rate 1000ml / h. ;

[0081] B. Get lutein ester, acerola powder and lycopene powder and mix, then with food-grade auxiliary material microcrystalline cellulose (consumption is 3% of lutein ester, acerola powder and lycopene powder gross weight ) and mix evenly, and then press into tablets, the weight of the tablet is 0.4g.

[0082] Embodiment 2 tablet index

Embodiment 3

[0084] Main formula:

[0085] Lycopene oil 180g, lutein ester 180g, acerola cherry powder 180g, β-cyclodextrin 900g.

[0086] Preparation:

[0087] a. Dissolve β-cyclodextrin in distilled water at 80°C, keep the temperature constant for 30 minutes, add 0.5% emulsifier soybean lecithin and lycopene oil (the ratio of core material to wall material is 1:5), and homogenize. Homogeneous conditions temperature 30°C, pressure 40MPa, spray drying to obtain lycopene powder, spray drying conditions: inlet temperature 170°C, outlet temperature 85°C, flow rate 1000ml / h. ;

[0088] B. Get lutein ester, acerola powder and lycopene powder and mix, then with food-grade auxiliary material microcrystalline cellulose (consumption is 3% of lutein ester, acerola powder and lycopene powder gross weight ) and mix evenly, and then press into tablets, the weight of the tablet is 0.4g.

[0089] Embodiment 3 tablet index

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Abstract

The invention discloses a lycopene composition with oxidation resistance and asthenopia relieving effects. The composition is prepared from, by weight, 10-50 parts of lycopene oil, 10-50 parts of lutein ester and 10-50 parts of west Indies cherries. Lycopene, lutein ester and west Indies cherries have a synergistic effect and have better oxidation resistance and asthenopia relieving effects. Meanwhile, the invention further discloses a technology for wrapping beta-cyclodextrin on lycopene oil, the problem that lycopene oil is not stable is effectively solved, and the quality of the product is improved.

Description

technical field [0001] The invention belongs to the field of health food, and in particular relates to a lycopene tablet capable of resisting oxidation and alleviating visual fatigue and a preparation method thereof. Background technique [0002] Lycopene, also known as ψ-carotene, belongs to isoprenoid compounds and is a kind of carotenoid. Since it was first isolated from tomatoes, it is called lycopene. Lycopene quenches singlet oxygen or captures peroxide free radicals by physical and chemical means. Singlet oxygen is a highly active oxygen free radical with cytotoxicity. The cell membrane and mitochondria are the most sensitive to it. It can interact with a variety of biological macromolecules in cells and cause damage to the cell membrane system by combining with molecules. Lycopene can accept the energy of different electronic excited states, absorb light energy and transfer the energy of singlet oxygen to lycopene through the process of singlet-singlet energy trans...

Claims

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Application Information

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IPC IPC(8): A23L33/00A23L33/105A23L33/115A23L19/00A23L29/10A23L29/30A23P10/30
CPCA23V2002/00A23V2200/222A23V2200/224A23V2200/30A23V2200/31A23V2250/213A23V2250/21A23V2250/5114
Inventor 时浩徐国华田智斌王文风王英燕
Owner JIANGSU SHENHUA PHARMA
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