Fully-automatic oxygen control animal tank

Abstract

A fully automatic oxygen-controlled animal cabin, belonging to the technical field of medical experiment equipment, which solves the problem of automatic control of low oxygen concentration in the animal cabin and the uniformity of the distribution of mixed gas in the animal cabin; the whole experimental equipment consists of nitrogen cylinders, Air pump, animal cabin, buffer tank, central processing unit, flow meter, distributor, several conduits, cables, etc.; by adjusting the concentration of nitrogen in the animal cabin, the effect of indirectly controlling the oxygen concentration is achieved; the size of the oxygen concentration and The time to maintain the hypoxic environment is automatically controlled by the central processing unit. The equipment is highly automated and does not require special personnel to wait; the use of flow meters, distributors and buffer tanks reduces or even eliminates the damage of small jets of gas to small animals. , has the advantages of uniform and gentle air supply, and eliminates the phenomenon of uneven oxygen concentration distribution in the animal cabin from the source.

Description

technical field [0001] The invention belongs to the technical field of medical experiment equipment, and relates to experimental animal cabin equipment, in particular to a fully automatic oxygen-controlled animal cabin. Background technique [0002] Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a sleep-induced respiratory disease, clinically manifested as nocturnal sleep snoring, apnea and daytime sleepiness. Apnea can cause recurrent nocturnal hypoxia and hypercapnia, which can lead to complications such as hypertension, coronary heart disease, diabetes and cerebrovascular disease, and even sudden death at night. At present, there is no ideal animal model of OSAHS, and small animals are placed in intermittent hypoxic environment to simulate the pathological process of sleep apnea in OSAHS patients, so as to study the pathogenic mechanism of OSAHS. [0003] The existing intermittent hypoxia device for animals adopts a semi-automatic system mainly based on time contro...

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Problems solved by technology

[0003] The existing intermittent hypoxia device for animals adopts a semi-automatic system mainly based on time control, such as the patent application 201110205532.5, so there are many technical problems: the oxygen concentration is not well controlled, which often causes the oxygen concentration in the cabin to be different from the set value. Large deviation; Oxygen is consumed due to the installation of oxygen cylinders in the device, thus increasing the cost of the experiment; the animal cabin is an open structure, and the waste of oxygen and nitrogen is serious; in addition, oxygen and nitrogen are directly passed into the animal cabin by a catheter , so the oxygen distribution in the animal compartment is uneven

Some areas are enriched with nitrogen, causing the oxygen concentration in this area to greatly deviate from the set value, which not only seriously affects the accuracy and reliability of the experimental results, but also directly causes severe hypoxia or even suffocation of small animals staying in the area; The gas input in the tank is not depressurized, and there is a phenomenon that the small jet stream of gas directly faces the small animals, which is not conducive to the cultivation of small animals

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