Anti-acne cream based on high-purity herbal extract, and preparation method of anti-acne cream

The technology of extract and acne-removing cream is applied to the field of acne-removing cream based on high-purity herbal extract and its preparation, which can solve the problems of floating effect, unstable performance, limited efficacy of acne-removing combination, etc. The ingredients are stable and the effect of improving immunity

Active Publication Date: 2016-06-15
GUANGZHOU BAICAOTANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] It can be seen from the above prior art that the traditional Chinese medicine combination with heat-clearing, detoxifying, cooling blood and expelling wind is used as a functional raw material and compounded with other raw materials to obtain a composition with anti-acne function. However, there are not many requirements for the purity of the traditional Chinese medicine components in the anti-acne combination. See, therefore the efficacy of the anti-acne combination prepared is limited, the effect fluctuates greatly, and the performance is unstable

Method used

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  • Anti-acne cream based on high-purity herbal extract, and preparation method of anti-acne cream
  • Anti-acne cream based on high-purity herbal extract, and preparation method of anti-acne cream

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] (1) In parts by weight, 5 parts of Centella asiatica, 8 parts of Polygonum cuspidatum, 3 parts of Scutellaria baicalensis, 2 parts of tea leaves, 4 parts of Glycyrrhiza glabra, 5 parts of mother chrysanthemum, 3 parts of rosemary, 5 parts of white willow, 6 parts of fruit medicine, 10 parts of salvia miltiorrhiza, 5 parts of yellow gentian, 8 parts of loquat leaves, 5 parts of licorice root, 4 parts of honeysuckle flower, 3 parts of marigold, and 5 parts of daisy. Powder, mixed in proportion, firstly add 80% ethanol aqueous solution at a material ratio of 1:8, ultrasonically disperse, heat reflux at 80°C for 2 hours, then add 60% ethanol aqueous solution at a material ratio of 1:5, and ultrasonically disperse , extracted under heat reflux at 75° C. for 1 h, and the filtrate was concentrated by rotary evaporation until it had no alcohol smell, and an extract of natural herbal plants with an extraction rate of 80% was obtained.

[0029] (2) Centrifuge the extract of natur...

Embodiment 2

[0032] (1) In parts by weight, 20 parts of Centella Asiatica, 25 parts of Polygonum cuspidatum, 16 parts of Scutellaria baicalensis, 8 parts of tea leaves, 12 parts of Glycyrrhiza glabra, 10 parts of mother chrysanthemum, 9 parts of rosemary, 15 parts of white willow, Tsaoguo 14 parts of medicine, 20 parts of salvia miltiorrhiza, 10 parts of yellow gentian, 18 parts of loquat leaves, 9 parts of licorice root, 19 parts of honeysuckle, 11 parts of marigold, and 13 parts of daisy. After washing and drying, cut and grind into powder , mixed in proportion, firstly add 95% ethanol aqueous solution at a material ratio of 1:10, ultrasonically disperse, heat reflux at 100°C for 4 hours, and then add 80% ethanol aqueous solution at a material ratio of 1:6, ultrasonically disperse, After extraction at 80° C. for 2 hours, the filtrate was concentrated by rotary evaporation until it had no alcohol smell, and an extract of natural herbal plants with an extraction rate of 90% was obtained.

...

Embodiment 3

[0036] (1) In parts by weight, 10 parts of Centella asiatica, 13 parts of Polygonum cuspidatum, 8 parts of Scutellaria baicalensis, 6 parts of tea leaves, 8 parts of Glycyrrhiza glabra, 8 parts of chamomile, 6 parts of rosemary, 12 parts of white willow, Tsaoko 11 parts of medicine, 14 parts of salvia miltiorrhiza, 6 parts of yellow gentian, 12 parts of loquat leaves, 7 parts of licorice root, 14 parts of honeysuckle, 6 parts of marigold, and 8 parts of daisy. After washing and drying, cut and grind into powder , mixed in proportion, firstly add 85% ethanol aqueous solution at a material ratio of 1:98-10, ultrasonically disperse, heat reflux at 90°C for 3 hours, then add 70% ethanol aqueous solution at a material ratio of 1:5, and ultrasonically disperse Disperse, extract under reflux at 75°C for 1.5h, and concentrate the filtrate by rotary evaporation until it has no alcohol smell, and obtain the extract of natural herbal plants with an extraction rate of 85%.

[0037] (2) Ce...

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Abstract

The invention provides anti-acne cream based on high-purity herbal extract, and a preparation method of the anti-acne cream. The preparation method concretely comprises the following steps: (1) cleaning natural herbaceous plants, drying the cleaned herbaceous plants in the air, then cutting the dried herbaceous plants and grinding into powder, mixing the powder of the herbaceous plants according to proportion, adding an ethanol water solution into the mixture, carrying out ultrasonic dispersion, carrying out heat reflux extraction for twice, and carrying out rotary evaporation and concentration on filtrate until the filtrate is free from alcohol taste to obtain extract of the natural herbaceous plants; (2) centrifuging the extract of the natural herbaceous plants and taking supernatant of the extract, putting the supernatant into dry macroporous resin, standing still and carrying out suction filtration; after absorption, transferring the macroporous resin into a 80-90% of ethanol water solution, standing still and carrying out suction filtration; taking out the macroporous resin, carrying out rotary evaporation on filtrate until the filtrate is free from alcohol taste to obtain purified extract of the natural herbaceous plants; (3) mixing auxiliary agents, heating mixture up to 80-90 DEG C, stirring the heated mixture until the mixture is completely dissolved, cooling to 45-50 DEG C, adding the purified extract of the natural herbaceous plants into the mixture, evenly stirring, carrying out heat preservation, and then carrying out rotary evaporation until the mixture is in a cream state to obtain the anti-acne cream based on the high-purity herbal extract.

Description

Technical field: [0001] The invention belongs to the technical field of daily cosmetics, and in particular relates to an acne-removing ointment based on high-purity herbal extracts and a preparation method thereof. Background technique: [0002] Acne, also known as pimples, acne and pimples, is a chronic inflammatory disease that occurs in the pilosebaceous glands. It mainly occurs on the face and back of young men and women in adolescence and adulthood. Fuzz, employment, social interaction, marriage and childbearing, etc. Acne is related to factors such as increased androgen levels, increased sebum secretion, hyperkeratosis of the hair follicle duct, and propionibacterium infection. Traditional treatment methods require the use of antibiotics, androgen antagonists, and retinoic acid drugs for treatment, but the side effects obvious. With the continuous improvement of people's living standards, people pay more and more attention to the environmental protection, safety and ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61Q19/00A61Q19/02A61Q17/00A61P17/10
CPCA61K8/97A61K36/064A61K36/23A61K36/28A61K36/287A61K36/355A61K36/484A61K36/515A61K36/53A61K36/537A61K36/539A61K36/704A61K36/73A61K36/76A61K36/82A61K36/87A61K36/906A61Q17/005A61Q19/00A61Q19/02A61K2300/00
Inventor 胡海威丁靓闫永平郑辉严辉
Owner GUANGZHOU BAICAOTANG PHARMA
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