Method for preparing environment-friendly alpha-arbutin by using bioenzyme reaction and water crystallization purification

An environmentally friendly and arbutin technology, applied in fermentation and other directions, can solve the problems of difficulty in ensuring the complete removal of organic solvents, large safety hazards, and low efficiency, and achieve low cost, low allergenicity, and good stability.
CN105671107AInactive Publication Date: 2016-06-15广东乐尔康生物科技股份有限公司

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
广东乐尔康生物科技股份有限公司
Publication Date
2016-06-15
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a method for preparing environment-friendly alpha-arbutin by using bioenzyme reaction and water crystallization purification. The preparation method of the environment-friendly alpha-arbutin comprises the following steps: bioenzyme-based alpha-arbutin synthesis: adding a 5-50 g / L alpha-arbutin enzyme into an enzyme reaction base solution, and reacting at 30-50 DEG C to obtain an alpha-arbutin primary product solution, wherein the enzyme reaction base solution for bioenzyme-based alpha-arbutin synthesis is composed of 5.0-15.0 wt% of disaccharide, 0.5-5.0 wt% of 1,4-hydroquinone, 0.02-0.08 wt% of sodium hydroxide, 0.1-2.0 wt% of aid and the balance of purified water; and purifying the alpha-arbutin primary product by water crystallization separation 3-7 times, thereby obtaining the environment-friendly alpha-arbutin. The method for preparing alpha-arbutin has the advantages of simple technique, high safety and low cost, and is suitable for mass production. The obtained alpha-arbutin product is environment-friendly, has the advantages of high purity, high stability and low sensitization, and can be used for various whitening products.
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Description

technical field

[0001] The invention relates to the technical field of cosmetic raw materials, and relates to the preparation of glycosides, in particular to a method for preparing environmentally friendly α-arbutin by utilizing biological enzyme reaction and water crystallization purification. Background technique

[0002] α-Arbutin exists in plants such as bearberry and lingonberry, which can effectively inhibit the activity of tyrosinase in the skin and reduce the deposition of tyrosinase in the skin. It is a non-irritating, non-allergic and compatible Strong natural whitening active substance, which has bleaching, anti-pigmentation and anti-freckle effects on the skin.

[0003] In the production process of α-arbutin, the preparation method and separation and purification technology play a vital role in the final quality of the product. At present, there are many methods for preparing α-arbutin. The more efficient and green production processes include fermentation metho...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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