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Hydrophilic polyurethane wound dressing for skin and preparation method of dressing

A hydrophilic polyurethane and wound dressing technology, which is used in medical science, absorbent pads, bandages, etc., can solve the problems of poor ability to absorb wound exudate, easy to cause inflammation, secondary trauma, etc., to achieve long-lasting moisturizing time, equipment Effects with low requirements and good moisturizing properties

Inactive Publication Date: 2016-06-22
SUZHOU BEC BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The traditional dressing is absorbent cotton gauze, which has poor ability to absorb wound exudate and is not waterproof, and it is easy to cause secondary trauma and inflammation during the replacement process

Method used

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  • Hydrophilic polyurethane wound dressing for skin and preparation method of dressing
  • Hydrophilic polyurethane wound dressing for skin and preparation method of dressing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A kind of hydrophilic polyurethane wound dressing for skin, comprising the following components in parts by weight: 50 parts of polyurethane, 10 parts of n-butyl α-cyanoacrylate, 5 parts of hyaluronic acid, 5 parts of carboxymethyl cellulose, 5 parts of silk fibroin, 15 parts of sodium alginate, 1 part of succinyl chitosan, 1 part of mannose, and 1 part of diclofenac diethylammonium salt.

[0020] The preparation method of hydrophilic polyurethane wound dressing for skin is as follows:

[0021] (1) each component is taken by weight;

[0022] (2) Melt polyurethane, α-n-butyl cyanoacrylate, hyaluronic acid and carboxymethyl cellulose in a reaction kettle, the temperature is controlled at 120°C, add sodium alginate after complete melting, and keep warm for 30 minutes;

[0023] (3) Under the condition of constant stirring, slowly add the rest of the raw materials into the reaction kettle, and after being completely mixed evenly, cool down and defoam;

[0024] (4) Apply th...

Embodiment 2

[0026] A kind of hydrophilic polyurethane wound dressing for skin, comprising the following components in parts by weight: 60 parts of polyurethane, 16 parts of n-butyl α-cyanoacrylate, 8 parts of hyaluronic acid, 7 parts of carboxymethyl cellulose, 8 parts of silk fibroin, 20 parts of sodium alginate, 5 parts of succinyl chitosan, 2 parts of mannose, 1 part of diclofenac diethylammonium salt.

[0027] The preparation method of hydrophilic polyurethane wound dressing for skin is as follows:

[0028] (1) each component is taken by weight;

[0029] (2) Melt polyurethane, α-n-butyl cyanoacrylate, hyaluronic acid and carboxymethyl cellulose in a reaction kettle, the temperature is controlled at 124°C, add sodium alginate after complete melting, and keep warm for 35 minutes;

[0030] (3) Under the condition of constant stirring, slowly add the rest of the raw materials into the reaction kettle, and after being completely mixed evenly, cool down and defoam;

[0031] (4) Apply the ...

Embodiment 3

[0033] A kind of hydrophilic polyurethane wound dressing for skin, comprising the following components in parts by weight: 62 parts of polyurethane, 18 parts of n-butyl α-cyanoacrylate, 10 parts of hyaluronic acid, 8 parts of carboxymethyl cellulose, 9 parts of silk fibroin, 22 parts of sodium alginate, 6 parts of succinyl chitosan, 2 parts of mannose, 2 parts of diclofenac diethylammonium salt.

[0034] The preparation method of hydrophilic polyurethane wound dressing for skin is as follows:

[0035] (1) each component is taken by weight;

[0036] (2) Melt polyurethane, n-butyl α-cyanoacrylate, hyaluronic acid and carboxymethyl cellulose in a reaction kettle with the temperature controlled at 128°C, add sodium alginate after complete melting, and keep warm for 40 minutes;

[0037] (3) Under the condition of constant stirring, slowly add the rest of the raw materials into the reaction kettle, and after being completely mixed evenly, cool down and defoam;

[0038] (4) Apply t...

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Abstract

The invention provides a hydrophilic polyurethane wound dressing for skin and a preparation method thereof. The dressing comprises the following components: polyurethane, n-butyl α-cyanoacrylate, hyaluronic acid, carboxymethyl cellulose, silk fibroin, Sodium alginate, succinochitosan, mannose, diclofenac diethylammonium salt. Preparation method: Weigh each component by weight; melt polyurethane, n-butyl α-cyanoacrylate, hyaluronic acid and carboxymethyl cellulose in a reaction kettle, add sodium alginate after complete melting, and keep warm ; Under the condition of constant stirring, slowly add the rest of the raw materials into the reaction kettle, and after being completely mixed, cool down and defoam; spread the mixture evenly on the base cloth, cool down, and cover the peeling layer on the coated colloid layer , that is. Compared with the prior art, it has good moisturizing performance, long-lasting moisturizing time, no irritation to skin, simple preparation method, low equipment requirements, and is suitable for large-scale popularization and application.

Description

technical field [0001] The invention relates to the field of biomedical dressings, in particular to a hydrophilic polyurethane wound dressing for skin and a preparation method thereof. Background technique [0002] In recent years, the problem of aging in various countries has become increasingly serious, the incidence of diabetes and obesity has continued to increase, and the demand for chronic wound care such as decubitus ulcers and refractory ulcers among the elderly is increasing. The medical dressing market has a large room for growth. Research on wound healing shows that the purpose of using dressings is not only to cover the wound surface, but also to promote wound healing. According to the "moist wound healing" theory, wounds heal faster in a moist environment. [0003] The traditional dressing is absorbent cotton gauze, which has poor ability to absorb wound exudate and is not waterproof, and it is easy to cause secondary trauma and inflammation during the replacem...

Claims

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Application Information

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IPC IPC(8): A61L15/26A61L15/20A61L15/28A61L15/32A61L15/42
CPCA61L15/26A61L15/20A61L15/28A61L15/32A61L15/42
Inventor 李苏杨徐勤霞李文遐
Owner SUZHOU BEC BIOLOGICAL TECH
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