Full-automatic capillary electrophoresis device suitable for separation analysis of space biological sample

Abstract

The invention provides a full-automatic capillary electrophoresis device suitable for separation analysis of a space biological sample to efficiently and quickly analyze the space biological sample.The two ends of a sample feeding and cleaning unit are connected with electrophoresis separation capillaries at the common ends of two three-way electromagnetic valves respectively, and the common end of an electric multi-position selector valve is connected with the inlet end of a peristaltic pump.A constant temperature unit comprises four electrophoresis separation capillary clamping box fixing threaded holes, capillary containing grooves and a temperature control assembly.An optical detection unit is a confocal type laser-induced fluorescence detection device.An electric displacement unit comprises a perpendicular direction displacement table and a rotation displacement table.The two ends of a high-voltage power supply are connected with electrodes respectively.A photovoltaic conversion unit is composed of a photo-multiplier tube and a gain control circuit.A signal processing unit is composed of a data acquisition card and a computer.Light signals are collected and processed, and qualitative and quantitative analysis of the sample is achieved.

Description

technical field [0001] The invention belongs to the field of space biochemical analysis, and in particular relates to a fully automatic capillary electrophoresis device suitable for separation and analysis of space biological samples. Background technique [0002] Under the action of an electric field, charged particles move toward an electrode opposite to their charged nature, which is called electrophoresis (Electrophoresis, EP). The technique of using charged particles to move at different speeds in an electric field to achieve separation is called electrophoresis. In 1807, it was first discovered by Reuss of Moscow University in Russia. In 1937, Tisus successfully developed an interface electrophoresis instrument for serum protein electrophoresis, which was carried out in the free solution of a U-shaped tube. After electrophoresis, the optical system was used to make the refractive index difference formed by various proteins into a curve image, and the serum protein It...

AI Technical Summary

Problems solved by technology

[0008] Aiming at the problem that the structure, size and weight of commercialized capillary electrophoresis instruments do not meet the actual needs of space biochemical analysis, the present invention provides a fully automatic capillary electrophoresis device suitable for the separation and analysis of space biological samples, which only requires astronauts to load samples and press the instrument Press the power button, the instrument will automatically execute the operation process including cleaning, sampling, electrophoresis separation, data acquisition and analysis, and experimental data storage, so as to realize efficient and rapid analysis of space biological samples

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