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Degradable antibacterial hemostatic fiber pad and preparation method thereof

A kind of technology of hemostatic fiber, hydroxyethyl cellulose

Inactive Publication Date: 2016-07-20
王泽陆
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the prior art, the traditional hemostatic fiber material usually uses hemostatic gauze, which is mainly made of cotton, linen, etc., which has poor antibacterial and antibacterial ability, gauze fibers are easy to cause foreign body rejection and affect wound healing, and are easy to contact with wound tissue during use. Adhesion, causing secondary damage and other problems, and the waste treatment process after use is complicated and easy to pollute the environment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] The degradative antibacterial and hemostatic fiber pad described in this embodiment includes the following components in parts by weight: 30 parts of polyurethane, 21 parts of D-polylactic acid, 16 parts of L-glycine, 12 parts of silk protein, 8 parts of dextran, hydroxyl 13 parts of ethyl cellulose, 2 parts of polyvinylpyrrolidone, 5 parts of citric acid, 3 parts of antibacterial agent, 3 parts of sodium hydroxide, 8 parts of trimethylolpropane, 6 parts of sodium trimetaphosphate, 18 parts of ethanol, double distilled 45 parts of water.

[0024] The antibacterial agent is a mixture of azone, povidone iodine and wintergreen oil with a mass ratio of 2:1:4.

[0025] The preparation method of the degradable antibacterial and hemostatic fiber pad described in this embodiment, the steps are as follows:

[0026] (1) In parts by weight, sequentially add polyurethane, D-polylactic acid, hydroxyethyl cellulose, polyvinylpyrrolidone, citric acid, antibacterial agent, trimethylol...

Embodiment 2

[0032] The degradable, antibacterial and hemostatic fiber pad described in this embodiment includes the following components in parts by weight: 45 parts of polyurethane, 34 parts of D-polylactic acid, 29 parts of L-glycine, 24 parts of silk protein, 17 parts of dextran, hydroxyl 20 parts of ethyl cellulose, 9 parts of polyvinylpyrrolidone, 11 parts of citric acid, 7 parts of antibacterial agent, 6 parts of sodium hydroxide, 14 parts of trimethylolpropane, 12 parts of sodium trimetaphosphate, 30 parts of ethanol, double distilled 60 parts of water.

[0033] The antibacterial agent is a mixture of azone, povidone iodine and wintergreen oil with a mass ratio of 2:1:4.

[0034] The preparation method of the degradable antibacterial and hemostatic fiber pad described in this embodiment, the steps are as follows:

[0035] (1) In parts by weight, sequentially add polyurethane, D-polylactic acid, hydroxyethyl cellulose, polyvinylpyrrolidone, citric acid, antibacterial agent, trimeth...

Embodiment 3

[0041] The degradative antibacterial and hemostatic fiber pad described in this embodiment includes the following components in parts by weight: 37 parts of polyurethane, 27 parts of D-polylactic acid, 23 parts of L-glycine, 18 parts of silk protein, 12 parts of dextran, hydroxyl 16 parts of ethyl cellulose, 5 parts of polyvinylpyrrolidone, 8 parts of citric acid, 5 parts of antibacterial agent, 5 parts of sodium hydroxide, 11 parts of trimethylolpropane, 9 parts of sodium trimetaphosphate, 24 parts of ethanol, double distilled 52 parts of water.

[0042] The antibacterial agent is a mixture of azone, povidone iodine and wintergreen oil with a mass ratio of 2:1:4.

[0043] The preparation method of the degradable antibacterial and hemostatic fiber pad described in this embodiment, the steps are as follows:

[0044] (1) In parts by weight, sequentially add polyurethane, D-polylactic acid, hydroxyethyl cellulose, polyvinylpyrrolidone, citric acid, antibacterial agent, trimethyl...

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PUM

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Abstract

The invention discloses a degradable antibacterial hemostatic fiber pad and a preparation method thereof. The degradable antibacterial hemostatic fiber pad comprises the following components in parts by weight: polyurethane, D-polylactic acid, L-glycine, silk protein, dextran, hydroxyethyl cellulose, polyvinylpyrrolidone, citric acid, an antibacterial agent, sodium hydroxide, trimethylolpropane, sodium trimetaphosphate, 18 to 30 parts of ethanol, and double distilled water. The hemostatic fiber pad provided by the invention has a bleeding amount of less than 0.13g and an antibacterial rate of more than 99.1%, showing a good hemostatic effect. In addition, the hemostatic fiber pad has good biocompatibility and short wound healing time, is easily torn off without damaging tissues, does not bring secondary damage, and has good application prospects.

Description

technical field [0001] The invention belongs to the field of hemostatic materials, and in particular relates to a degradable antibacterial and hemostatic fiber pad and a preparation method thereof. Background technique [0002] In daily life, whether it is emergency treatment of various sudden accidents or trauma hemostasis in the process of treatment, it is very important for patients to effectively and quickly stop bleeding locally; The death rate from the cause of hemorrhage remains high. Therefore, it is of great significance to develop an effective rapid hemostatic material to accelerate the speed of coagulation, and to reduce the mortality rate caused by excessive blood loss. [0003] In the prior art, the traditional hemostatic fiber material usually uses hemostatic gauze, which is mainly made of cotton, linen, etc., which has poor antibacterial and antibacterial ability, gauze fibers are easy to cause foreign body rejection and affect wound healing, and are easy to ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/26A61L15/32A61L15/20A61L15/28A61L15/24A61L15/40A61L15/42A61L15/46
CPCA61L15/26A61L15/20A61L15/24A61L15/28A61L15/32A61L15/40A61L15/42A61L15/46A61L2300/112A61L2300/20A61L2300/21A61L2300/232A61L2300/236A61L2300/252A61L2300/30A61L2300/404A61L2400/04
Inventor 王泽陆
Owner 王泽陆
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