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Preparation for treating dermatophytosis

A preparation, athlete's foot technology, applied in the direction of aerosol delivery, medical preparations containing active ingredients, antifungal agents, etc. Not easy to recur, less irritating effect

Inactive Publication Date: 2016-08-10
昆明铭垦生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because beriberi has a high incidence rate in my country, the potential market capacity of medicines for treating beriberi is very large. However, although the current products for treating beriberi all have certain anti-ringworm effects, some products have a long cure period.
It is easy to relapse after being cured. Some products are irritating to the skin, and some products have an unpleasant smell and the effect is not ideal.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] 30 parts of Sophora flavescens extract, 10 parts of Vitex bark extract and 5 parts of triclosan are respectively pulverized into fine powder and mixed, then add talcum powder of 1 times the total weight of the drug, and pearl powder of 1 times the total weight of the drug After passing through an 80-mesh sieve, mix evenly and pack separately to obtain a powder.

Embodiment 2

[0016] 30 parts of Sophora flavescens extract, 10 parts of Vitex bark extract and 5 parts of triclosan were respectively crushed into fine powder and mixed, passed through an 80 mesh sieve, dissolved in 850 parts of ethanol, and 1.2% of the total weight of the drug was added in dimethyl methylene The sulfone is fully stirred and mixed, filtered through a microporous membrane, and filled to obtain a spray.

Embodiment 3

[0018] 30 parts of Sophora flavescens extract, 10 parts of Vitex bark extract and 5 parts of triclosan were respectively crushed into fine powder and mixed, passed through an 80 mesh sieve and dissolved in 870 parts of ethanol, and 5% of the total weight of the drug was added Laurazoxazone and 3% borneol, fully stirred and mixed, filtered through a microporous membrane, and filled to obtain a spray.

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PUM

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Abstract

The invention discloses a preparation for treating dermatophytosis. The preparation mainly comprises the following components in parts by weight: 10-50 parts of a sophora angustifolia root extract;, 10-50 parts of a cortex pseudolaricis extract, 2-8 parts of triclosan and auxiliary materials. The preparation is prepared into a powder medicine or a spray. The powder medicine is obtained by the following steps: respectively grinding the sophora angustifolia root extract, the cortex pseudolaricis extract and triclosan into fine powder; then adding talcum powder which is 0.7-2 times the total amount of the medicine and pearl powder which is 0.7-2 times the total amount of the medicine; sieving with an 80-mesh sieve; then uniformly mixing, and subpackaging. The spray is obtained by the following steps: respectively grinding the sophora angustifolia root extract, the cortex pseudolaricis extract and triclosan into fine powder; sieving with the 80-mesh sieve; dissolving the fine powder in 60% ethanol; adding dimethyl sulfoxide which is 1.2% of the total amount of the spray, and fully stirring and mixing; filtering with a microfiltration membrane, and canning. The pharmaceutical formulation provided by the invention is respectively prepared into the powder medicine and the spray with dermatophytosis treatment effects, and meanwhile inhibits and kills fungi in shoes and on feet; due to double treatment effects, the curative effect is effectively improved, the treatment course is shortened, the dermatophytosis is unlikely to relapse after being healed, the preparation has high clinical use value.

Description

technical field [0001] The invention belongs to the technical field of medicine for external use, and in particular relates to a preparation for treating beriberi. Background technique [0002] Athlete's foot is the common name of tinea pedis, also known as "rotten feet", is a common skin disease caused by fungal (also known as toxin) infection; it is a very common fungal infectious skin disease, 70% of adults ~80% of the people have beriberi, but the severity is different; the disease is often aggravated in summer and relieved in winter, and some people do not heal all the year round; Thick cuticle, lack of sebum, abundant sweat glands, and moist feet are conducive to the growth and reproduction of mold. The clinical manifestations are blisters or erosions, itching, pain, etc. between the toes, the edge of the foot, and the sole of the foot, which brings a lot of inconvenience to the life of beriberi patients. Because beriberi has a high incidence rate in my country, the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/489A61K9/14A61K9/12A61P17/00A61P31/10A61K31/085A61K33/12A61K35/618A61K31/045
CPCA61K36/489A61K9/12A61K9/14A61K31/045A61K31/085A61K33/12A61K35/618A61K36/15A61K47/20A61K2300/00
Inventor 王太银
Owner 昆明铭垦生物科技有限公司
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