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Traditional Chinese medicine preparation for acute kidney injury protection and preparation method

A technology for acute kidney injury and traditional Chinese medicine preparations, which can be used in pharmaceutical formulations, medical preparations with inactive ingredients, and medical preparations containing active ingredients, etc., and can solve problems such as electrolyte balance disorders and aggravation of illnesses.

Inactive Publication Date: 2016-08-10
THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the treatment of diseases requires the use of drugs that may damage the kidneys, such as gentamicin, amikacin, vancomycin, etc., so there are uncertain risk factors, and for the treatment of complications of acute kidney injury, It often leads to electrolyte balance disorder in the body, which in turn aggravates the condition

Method used

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  • Traditional Chinese medicine preparation for acute kidney injury protection and preparation method
  • Traditional Chinese medicine preparation for acute kidney injury protection and preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] Embodiment 1 honey pill 1

[0069] Weigh 10g Bupleurum, 40g Raw Scutellaria, 15g Hedyotis diffusa, 10g Golden Buckwheat, 10g Shiwei, 20g Imperata Rhizome, 20g Dandelion, 20g Wild Chrysanthemum, 15g Commelina, mix together, add 1.2kg of alcohol concentration Soak for 2 hours at 80%, heating and extracting 2 times, each time for 2 hours, to obtain the extract, combine the extracts, and filter the residue for later use. Press and concentrate to remove the solvent, obtain a dry paste, crush it into the first powder, weigh 35g of raw rhubarb, 35g of salvia miltiorrhiza, 10g of cortex moutan, 20g of red peony, 25g of Caulis Spatholobus, 10g of Rhizoma Chuanxiong, 25g of angelica, 20g of astragalus, osmanthus osmanthus Branch 10g, Codonopsis 25g, Poria cocos 10g, Stir-fried Atractylodes macrocephala 15g, Pinellia 10g, Tangerine peel 25g, Perilla leaf 10g, Huoxiang 10g, Magnolia officinalis 25g, Coix seed 15g, Alisma 15g and Plantain 20g, mixed together , add water to decoct 2...

Embodiment 2

[0070] Embodiment 2 honey pill 2

[0071] Weigh 10g Bupleurum, 40g Raw Scutellaria, 15g Hedyotis diffusa, 10g Golden Buckwheat, 10g Shiwei, 20g Imperata Rhizome, 15g Dandelion, 20g Wild Chrysanthemum, 15g Commelina, mix together, add 1.2kg of alcohol concentration Soak for 2 hours at 80%, heating and extracting 2 times, each time for 2 hours, to obtain the extract, combine the extracts, and filter the residue for later use. Press and concentrate to remove the solvent, obtain a dry paste, crush it into the first powder, weigh 30g of raw rhubarb, 30g of salvia miltiorrhiza, 10g of cortex moutan, 20g of red peony, 20g of Caulis Spatholobus, 10g of Rhizoma Chuanxiong, 25g of angelica, 20g of astragalus, osmanthus osmanthus Branch 10g, Codonopsis 25g, Poria cocos 5g, Stir-fried Atractylodes macrocephala 15g, Pinellia 10g, Tangerine peel 20g, Perilla leaf 10g, Huoxiang 10g, Magnolia officinalis 20g, Coix seed 15g, Alisma 10g and Plantain 15g, mixed together , add water to decoct 2 ...

Embodiment 3

[0072] Embodiment 3 honey pill 3

[0073] Raw rhubarb 30g~35g, Bupleurum 10g~15g, raw skullcap 40g~45g, dandelion 15g~20g, diffusa 15g~20g, golden buckwheat 10g~15g, wild chrysanthemum 20g~25g, Shiwei 10g~15g, white 20g-25g of Chine root, 15g-20g of Commelina miltiorrhiza, 30g-35g of Salvia miltiorrhiza, 10g-15g of Moutan cortex, 20g-25g of red peony, 20g-25g of Caulis Spatholobus, 10g-15g of Chuanxiong, 25g-30g of angelica, 20g-25g of astragalus , Guizhi 10g-15g, Codonopsis 25g-30g, Poria cocos 5g-10g, Stir-fried Atractylodes macrocephala 15g-20g, French pinellia 10g-15g, tangerine peel 20g-25g, perilla leaves 10g-15g, Huoxiang 10g-15g, magnolia officinalis 20g~25g, coix seed 15g~20g, Alisma 10g~15g and plantain 15g~20g

[0074] Weigh 15g Bupleurum, 45g Raw Scutellaria, 20g Hedyotis diffusa, 15g Golden Buckwheat, 15g Shiwei, 25g Imperata Rhizome, 20g Dandelion, 25g Wild Chrysanthemum, 20g Commelina, mix together, add 1.5kg of alcohol concentration Soak for 2 hours at 80%, h...

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Abstract

The invention provides a traditional Chinese medicine preparation for acute kidney injury protection. The traditional Chinese medicine preparation is prepared from radix et rhizoma rhei, radix bupleuri, raw radix scutellariae, herba taraxac, hedyotis diffusa, rhizoma fagopyri dibotryis, flos chrysanthemi indici, folium pyrrosiae, rhizoma imperatae, herba commelinae, radix salviae miltiorrhizae, cortex moutan, radix paeoniae rubra, caulis spatholobi, rhizoma chuanxiong, radix angelica sinensis, radix astragali, ramulus cinnamomi, radix codonopsis, poria, stir-fried rhizoma atractylodis macrocephalae, rhizoma pinelliae preparatum, pericarpium citri reticulatae, folium perillae, agastache rugosa (Fisch. et Mey.) O. Ktze., cortex magnoliae officinalis, semen coicis, rhizoma alismatis and herba plantaginis. The traditional Chinese medicine preparation has the effects of clearing away heat and toxic materials, removing damp and turbid, regulating qi to disperse stagnation and maintaining vital qi, it is concluded through clinical practice that in combination with experimental research achievements, the traditional Chinese medicine preparation is proved to have a clinical effect of treating acute kidney injury and is applicable to clinical application and popularization.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine preparation for acute kidney injury protection and a preparation method. Background technique [0002] Acute kidney injury is a group of clinical syndromes, which refers to sudden (within 1-7d) and sustained (>24h) sudden decline in renal function, defined as an increase in Scr within 48 hours ≥ 26.5 μmol / L or an increase in the level of Scr ≥ 50% and (or) urine output <0.5mL / (kg·h) up to 6h. [0003] The treatment of acute kidney injury mainly includes removing the cause, maintaining a stable internal environment, nutritional support, dealing with complications, and blood purification. [0004] Although acute kidney injury is a relatively serious kidney disease, if treated in time, the patient can recover. Finding and eliminating the cause of the disease is the key to treatment. Severe acute kidney injury almost always ...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61K9/20A61K47/46A61P13/12
CPCA61K9/2068A61K36/076A61K36/11A61K36/232A61K36/233A61K36/236A61K36/284A61K36/287A61K36/288A61K36/344A61K36/481A61K36/486A61K36/532A61K36/535A61K36/537A61K36/539A61K36/54A61K36/575A61K36/65A61K36/68A61K36/70A61K36/708A61K36/71A61K36/748A61K36/752A61K36/88A61K36/884A61K36/8888A61K36/899A61K36/8994A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61K2300/00
Inventor 徐岩
Owner THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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