Medical cold compress plaster and preparation process thereof

A cold compress and site technology, which is applied in the directions of cooling devices for treatment, contraceptives, heating devices for treatment and treatment, etc., can solve the problem that it is difficult to completely fit the ice compress, infected wound parts, and the ice pack is easy to displace. and other problems, to achieve the effect of being conducive to local observation, good biocompatibility, and adjustable adhesion

Inactive Publication Date: 2016-08-24
HANGZHOU JIERSI BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although ice pack cold compress physiotherapy has a remarkable therapeutic effect, it is restricted by the inherent characteristics of existing ice packs. There are still many defects and deficiencies in ice pack therapy: for example, when the ice pack freezes when it is filled with cold, the ice pack will solidify into lumps, and it is very difficult to target the ice pack in emergency use. It is difficult to fit completely, especially the joints or body curves; the ice pack needs to be filled with cold to use, and it needs to be stored at low temperature for a long time, which is inconvenient to use; the ice pack is placed in the refrigerator, and the temperature is relatively low. The patient will feel uncomfortable when using the ice pack; there is basically no targeted treatment effect; the refrigerant in the ice pack leaks and infects the wound site; and when using it, the patient usually has to maintain a certain posture and cannot move, etc.
At present, there are also cold packs with colloidal refrigerants that do not freeze below zero, which can solve the problem of unsuitable products, but also cannot solve the problem of difficulty in fixing the product during use.
[0004] Patent 201310198916.8 discloses a testicular cold compress and its preparation method. In the formula of this patent, aluminum glycylate is added as a cross-linking agent, but there is no patch cross-linking regulator. During a small amount of testing, the test product can be processed, but In the process of large-scale production, if no cross-linking regulator is added, the polymer mixture will cross-link too quickly, and it is easy to fail to coat; in addition, after the polymer mixture is obtained, it is coated on the polyethylene film. , to make an attached preparation, and then apply the attached preparation on the non-woven fabric, and perform air cutting after coating
The method of this process is relatively backward, adding a lot of process steps, which is not conducive to large-scale production, time-consuming and laborious; at the same time, the polymer mixture is first coated on the polyethylene film, and the polymer mixture is easy to fall off; In the process of sticking on the non-woven fabric, the non-woven fabric is relatively soft, and the polymer mixture is relatively moist. The application of the polymer mixture and the non-woven fabric is difficult, and non-woven fabric wrinkles will appear, which is prone to waste products
[0005] Patent 201410026916.4 discloses a special nursing medical ice pack for cold compress of condyloma acuminata, which essentially adds an outer bag containing traditional Chinese medicine to the outside of the ice pack to achieve the effect of cold compress and drug administration at the same time, and is used for conservative treatment of condyloma acuminata, but the patent The design has the problem that it cannot be fixed. During use, the ice pack is easy to shift and fall off

Method used

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  • Medical cold compress plaster and preparation process thereof
  • Medical cold compress plaster and preparation process thereof
  • Medical cold compress plaster and preparation process thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Embodiment 1: A medical cold compress is composed of a support layer, a gel layer and an isolation layer; the shape of the medical cold compress is a crown with a four-finger structure conforming to the physiological curve of the application site. The gel layer is a hydrogel, which is formed by mixing two phases of oil phase and water phase. The specific mass percentages of the components of each phase and the preparation process are as follows,

[0045] The preparation process of the medical cold compress is as follows: 1) configure the oil phase first: add 0.05% triclosan and 0.04% menthol to completely dissolve the solution in 0.15% absolute ethanol; 0.01% vitamin E, 3% NP -700 and 3% AH-106X, 0.08% aluminum glycolate, 0.01% disodium ethylenediaminetetraacetate were added to 30% glycerin in turn, stirred evenly, and set aside after degassing; 2) Water phase configuration: 0.01% vitamin C. 0.2% Dissolve tartaric acid in 50% medical purified water. After the dissolutio...

Embodiment 2

[0047] Implementation 2: A medical cold compress is composed of a support layer, a gel layer and an isolation layer; the shape of the medical cold compress is similar to a sanitary napkin for women that conforms to the physiological curve of the site of use. The gel layer is a hydrogel, which is formed by mixing two phases of oil phase and water phase. The specific mass percentages of the components of each phase and the preparation process are as follows,

[0048] The preparation process of the described medical cold compress is as follows: 1) configure the oil phase first: add 0.1% triclosan and 0.1% menthol to completely dissolve the solution in 0.15% absolute ethanol; 0.1% vitamin E, 3% NP -700 and 3% AH-106X, 0.1% aluminum glycolate, 0.08% disodium ethylenediamine tetraacetate were added to 25% glycerin in turn, stirred evenly, and then used after degassing; 2) Water phase configuration: 0.1% vitamin C. Dissolve 0.4% tartaric acid in 50% medical purified water. After the ...

Embodiment 3

[0050] Implementation 3: A medical cold compress is composed of a support layer, a gel layer and an isolation layer; the shape of the medical cold compress is a split mask shape that conforms to the physiological curve of the application site. The gel layer is a hydrogel, which is formed by mixing two phases of oil phase and water phase. The specific mass percentages of the components of each phase and the preparation process are as follows,

[0051] The preparation process of the medical cold compress patch is as follows: 1) configure the oil phase first: add 0.05% triclosan and 0.05% menthol to completely dissolve the solution in 0.15% absolute ethanol; 0.1% vitamin E, 3% Add sodium polyacrylate, 3% AH-105X, 0.15% aluminum glycylate, and 0.1% disodium ethylenediaminetetraacetate to 25% glycerin in turn, stir evenly, and use after degassing; 2) Water phase configuration: 0.1% Vitamin C, 0.4% Dissolve tartaric acid in 50% medical purified water, after the dissolution is comple...

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Abstract

The invention provides a medical cold compress plaster. The medical cold compress plaster is composed of a support layer, a gel layer and an isolating layer, and has the special shape according with the physiological curve of the applied part. An oil phase and a water phase forming the hydrophilic gel layer respectively comprise the following components in percentage by weight: the oil phase: 20-35% of a dispersing agent, 5-7% of macromolecule resin, 0.05-0.15% of dihydroxyaluminium aminoacetate, 0.01-0.15% of ethylene diamine tetraacetic acid, 0.15% of absolute ethyl alcohol, 0.04-0.1% of menthol, 0.1-1% of vitamin E, and 0.05-0.1% of triclosan; the water phase: 0.2-0.8% of tartaric acid, 1.2-2% of carbomer, 0.5-1% of sodium carboxymethylcellulose, 0.01-0.1% of vitamin C, the balance of medical purified water, and the total weight percentage is 100%. A preparation process comprises the following steps: dispersing all the components of the oil phase into the dispersing agent, and uniformly stirring the components; dissolving all the components of the water phase into water, and uniformly stirring the components; mixing the water phase and the oil phase, uniformly stirring the water phase and the oil phase in a vacuum mixing pot, thus obtaining the hydrophilic gel substrate of the medical cold compress plaster, coating the support layer with the hydrophilic gel substrate, meanwhile covering with the isolating layer, and carrying out cutting, solidifying and packaging to obtain the needed medical cold compress plaster product.

Description

technical field [0001] The invention relates to a medical cold compress, in particular to a cold compress product used for analgesia and cold compress physiotherapy of closed soft tissues and local skin after laser surgery, and a preparation process thereof. Background technique [0002] Due to various reasons (such as acute soft tissue injury), or physiological needs of local cooling (such as local cooling of the scrotum to improve sperm motility), and local skin due to laser surgery or cryotherapy, cold compress physiotherapy is usually required. In order to reduce the local skin temperature, reduce swelling, stop bleeding, and relieve pain, so as to achieve the expected purpose of relieving or treating diseases. The traditional cold compress physiotherapy method mainly uses ice cubes or ice cube complexes (commonly referred to as ice packs) to stick to the affected part or specific parts, so as to achieve the purpose of cold compress analgesia. [0003] Although ice pack...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61F7/00A61P29/00A61P31/02
Inventor 俞瑞珺田复波舒朝锋
Owner HANGZHOU JIERSI BIOTECH CO LTD
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