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A method for removing the toxicity of ginkgo fruit based on a combination of physical and enzymatic methods

A ginkgo, enzymatic technology, applied in the directions of drug combination, sexual diseases, food science, etc., can solve the problems of loss of active and nutrient components, decline of ginkgo efficacy, environmental pollution, etc., and achieve high social and economic benefits and low processing costs.

Active Publication Date: 2019-11-08
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above two types of detoxification methods can remove the toxic components in ginkgo, there are mainly problems such as environmental pollution, loss of activity and nutritional components, and cumbersome process.
Due to the loss of activity and nutrients caused by solvent extraction and soaking, the efficacy of ginkgo will decrease

Method used

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  • A method for removing the toxicity of ginkgo fruit based on a combination of physical and enzymatic methods
  • A method for removing the toxicity of ginkgo fruit based on a combination of physical and enzymatic methods
  • A method for removing the toxicity of ginkgo fruit based on a combination of physical and enzymatic methods

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Embodiment 1 A kind of ginkgo toxicity compound processing detoxification method

[0045] (1) Take the ginkgo fruit freshly removed from the outer testa, and keep the water content of the ginkgo fruit higher than 60% in an environment with a temperature of 60° C. for 5 hours.

[0046] (2) Heat the ginkgo fruit to 100°C for 2 hours, and use a temperature-controlled drying oven for the heating method of the modified step. During the heating process, do not turn on the blast and seal it to maintain a certain humidity;

[0047] (3) Ginkgo fruit treated in the previous step is dried at a temperature of 90°C using temperature-controlled blast drying equipment, so that the water content of the ginkgo fruit is reduced to 30%, and the ginkgo fruit is manually dehulled, removed from the inner testa and germ;

[0048] (3) Ginkgo after removing the germ, further utilize the method and temperature described in (2) to dry, make moisture reach 10%.

[0049] Relevant composition detec...

Embodiment 2

[0050] Embodiment 2 A kind of ginkgo toxicity compound processing detoxification method

[0051] (1) Take the ginkgo fruit after removing the outer testa and drying it in the sun, and keep the water content of the ginkgo fruit higher than 50% in an environment with a temperature of 50° C. for 4 hours.

[0052] (2) Heat the ginkgo fruit to 90°C for 6 hours. The heating method of this step adopts infrared temperature-controlled drying equipment, and the heating process is moderately humidified and airtight to maintain a certain humidity;

[0053] (3) The ginkgo fruit treated in the previous step is dried and roughly dried at a temperature of 100°C using temperature-controlled microwave drying equipment, so that the water content of the ginkgo fruit is reduced to 35%, and the ginkgo fruit is shelled and seeded by a combination of manual and mechanical methods skin and germ;

[0054] (4) The ginkgo fruit after germination is directly used for the development of related ginkgo pr...

Embodiment 3

[0056] Embodiment 3 A kind of ginkgo toxicity compound processing detoxification method

[0057] (1) Take the ginkgo fruit, and keep the water content of the ginkgo fruit higher than 60% in an environment with a temperature of 70° C. for 2 hours.

[0058] (2) Heat the ginkgo fruit to 100°C for 2 hours. The heating method of this step adopts microwave temperature-controlled drying equipment, and the heating process is moderately humidified and airtight to maintain a certain humidity;

[0059] (3) Ginkgo fruit processed in the previous step is dried and roughly dried at a temperature of 100° C. using temperature-controlled microwave drying equipment, so that the water content of the ginkgo fruit is reduced to 35%. The ginkgo fruit is shelled by mechanical pressing, and the germ is removed by mechanical shock;

[0060] (4) The ginkgo fruit after removing the germ is further dried by infrared drying equipment to make the moisture reach 20%, reaching the humidity required for furt...

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Abstract

The invention discloses a ginkgo toxicity removal method based on a physical and enzymatic combination method. Through screening of substantial experiments, toxic component degrading enzymes of ginkgoes are used for bioconversion at the optimal temperature under optimal moisture conditions, toxic component 4-0-methyl pyridoxine and cyanogentic glycoside type components of the ginkgoes are removed efficiently, allergic protein in the ginkgoes are denatured and inactivated through high-temperature treatment, degraded products of the cyanogentic glycoside components are evaporated and removed, toxic component ginkgo acid is removed, moisture of the ginkgoes is reduced to some extent according to distribution of the ginkgo acid in the ginkgoes, and germ positions with the most gingko acid are removed manually or mechanically. The ginkgo toxicity removal method has the advantages of reasonableness in overall process design, high detoxification efficiency, environment protection, safety, non-existence of residual solvent, convenience in operation, low cost and capabilities of overcoming defects in the prior art and achieving industrial production.

Description

technical field [0001] The invention belongs to the technical field of processing agricultural and forestry products and medicines, and in particular relates to a processing method for detoxifying ginkgo based on a combination of physical and enzymatic methods. Background technique [0002] Ginkgo is the mature seed of Ginkgo biloba L. As a medicine, it was first recorded in "Shaoxing Wood Grass". It tastes sweet, bitter, astringent, and flat in nature; Leukorrhagia, leucorrhea, enuresis and frequent urination, etc., and has a certain effect of reducing phlegm, is an important medicine for the clinical treatment of cough, asthma and excessive phlegm in traditional Chinese medicine. Ginkgo is rich in starch, protein, fat, vitamins and trace elements such as calcium, phosphorus, potassium and selenium. Therefore, it is also a product of the same origin as medicine and food. It is recorded in Materia Medica that it has the functions of "invigorating qi and nourishing the hear...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A23L5/20A23L25/00A61K36/16A61P11/14A61P11/06A61P11/10A61P15/00A61P13/00
CPCA61K36/16
Inventor 段金廒钱大玮郭盛鲁学军宿树兰钱怡云
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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