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Gargle for relieving thirst, wetting throat and resisting bacteria and preparation method thereof

A technology of gargle and betel nut, applied in the fields of health care and medical treatment, can solve the problems of oral antibacterial, throat moisturizing, patients not feeling comfortable enough, and patients' compliance is not strong, so as to prolong the moisturizing time and improve the oral humidity. , the effect of improving oral health

Inactive Publication Date: 2016-09-07
江苏开源康达医疗器械有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the past, in order to solve the discomfort caused by stuffing, there were methods such as covering the mouth with wet gauze, cold compressing the mouth and nose, and rinsing the mouth with saline, etc., but the patients did not feel comfortable enough, and the postoperative dry throat still could not be effectively solved. , bad breath, and some methods are complicated to operate, which leads to poor patient compliance
[0004] Before the present invention was made, products such as water-soluble chitosan mouthwash and tea polyphenol mouthwash had been used clinically. Synergy can achieve antibacterial effect, resulting in narrow antibacterial spectrum, poor use effect, poor taste, unacceptable by patients, etc., which makes it difficult to popularize and apply
Chinese patent CN102274150 discloses a mouthwash using chitosan and linseed extract as active ingredients, which improves the taste of the mouthwash and prolongs the time for keeping the mouth moist , but this technical solution cannot completely solve the two major problems of oral antibacterial and throat moistening

Method used

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  • Gargle for relieving thirst, wetting throat and resisting bacteria and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041]Weigh the active extract of betel nut with a weight percentage of 2%, add it to hydrogen-rich water, stir at a speed of 2000r / min until it dissolves evenly, and let it stand for 5 hours; then add 1% carboxymethyl chitosan by weight, and open the incubator , stirred at a low speed for 2 hours at a temperature of T=50~60°C, fully dissolved, and filtered to remove impurities. Stand for 2 hours, filter with suction to obtain a solution, and add 0.5% by weight of inorganic salt, 5% by weight of glycerin, 0.05% by weight of peppermint oil, and 0.02% by weight of preservative, and stir to fully dissolve , and add hydrogen-rich water to 100%. The resulting solution is filled into a brown bottle according to the 200ml specification and sealed to obtain the initial product, which is sterilized and packed.

Embodiment 2

[0043] Weigh the active extract of betel nut with a weight percentage of 3%, add it to hydrogen-rich water, stir at a speed of 2000r / min until it dissolves evenly, and let it stand for 5 hours; then add 0.05% carboxymethyl chitosan in a weight percentage, and open the incubator , stirred at a low speed for 2 hours at a temperature of T=50~60°C, fully dissolved, and filtered to remove impurities. Stand for 2 hours, filter with suction to obtain a solution, and add 0.5% by weight of inorganic salt, 5% by weight of polyethylene glycol, 0.04% by weight of peppermint oil, and 0.02% by weight of calcium sorbate , stir to fully dissolve, and add hydrogen-rich water to 100%. The resulting solution is filled into a brown bottle according to the 200ml specification and sealed to obtain the initial product, which is sterilized and packed.

Embodiment 3

[0045] Weigh the active extract of betel nut with a weight percentage of 3%, add it to hydrogen-rich water, stir at a speed of 2000r / min until it dissolves evenly, and let it stand for 5 hours; then add 1% carboxymethyl chitosan by weight, and open the incubator , stirred at a low speed for 2 hours at a temperature of T=50~60°C, fully dissolved, and filtered to remove impurities. Stand for 2 hours, filter with suction to obtain the solution, and add 0.3% by weight of inorganic salt, 6% by weight of polyethylene glycol, 0.03% by weight of peppermint oil, and 0.01% by weight of sodium benzoate, Stir to fully dissolve, and add hydrogen-rich water to 100%. The resulting solution is filled into a brown bottle according to the 200ml specification and sealed to obtain the initial product, which is sterilized and packed.

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Abstract

The invention discloses a gargle for relieving thirst, wetting throat and resisting bacteria and a preparation method thereof. The gargle is composed of 0,01%-1% of carboxymethyl chitosan, 2%-4% of betel nut active extract, 0.2%-0.6% of inorganic salt, 1%-10% of humectant, 0.01-0.05% of oleum menthae, 0.01-0.05% of corrosion remover and the balance of hydrogen-rich water. The humectant is added into the gargle, so that the time of keeping oral cavity wet is prolonged; the hydrogen-rich water is added for effectively removing free radicals in the oral cavity, so that the happening of oral inflammation is restrained and the hazardous substance in the oral cavity is eliminated. The betel nut active extract can effectively increase the salivary secretion volume, can increase the humidity of oral cavity, can bring cooling feel and has a throat wetting effect. The preparation method provided by the invention is simple, the anti-microbial tooth-protecting effect is lasting and the gargle has no toxic effect to human body and tastes comfort.

Description

technical field [0001] The invention relates to a gargle and a preparation method thereof, in particular to an antibacterial gargle for relieving dry mouth, moistening the throat and a preparation method thereof, and belongs to the technical fields of medical and health care. Background technique [0002] Saliva is an indispensable mixed body fluid for the human body, and its component content is affected by various pathophysiological changes in the body. Its main functions are to moisten and dissolve food, produce taste sensations, and clean and protect the oral cavity. Generally speaking, under relatively constant conditions, a total saliva flow rate <0.2ml / 15min can be diagnosed as xerostomia. Radiation xerostomia can be diagnosed when the saliva secretion per minute in the resting state is less than 0.1-0.2ml. Xerostomia is a common symptom in dental clinics. Xerostomia is the patient's lack of saliva secretion, dry mouth, foreign body sensation, and burning sensat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61K8/92A61K8/73A61K8/34A61K8/20A61Q11/00A61P1/02
CPCA61K8/736A61K8/20A61K8/34A61K8/345A61K8/922A61K8/97A61K2800/5922A61Q11/00
Inventor 孙开源
Owner 江苏开源康达医疗器械有限公司
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