Composite growth factor skincare gel and preparation method thereof

A technology of complex growth factors and skin care gel, applied in the field of skin care gel and its preparation, to achieve the effects of high production efficiency, flattening skin redness, and repairing skin wounds and scars

Inactive Publication Date: 2016-10-26
朗肽生物制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is still no ideal skin care product for repairin

Method used

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  • Composite growth factor skincare gel and preparation method thereof
  • Composite growth factor skincare gel and preparation method thereof
  • Composite growth factor skincare gel and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A kind of complex growth factor skin care gel, it comprises the following raw material components by mass percentage:

[0031]

[0032] The active ingredient in the composite growth factor stock solution is rh-bFGF:KGF=1:0.6. The composite growth factor stock solution includes 0.0001% of the composite growth factor active ingredient and the balance of 20mmol / L phosphate buffer solution by mass percentage. At the same time, the mass ratio of the heparin sodium to the compound growth factor active ingredient in the compound growth stock solution is 1:1-3.

[0033] Preparation:

[0034] a) Preparation of skin care gel matrix: Weigh carbomer 940NF according to the mass percentage of raw materials, add water for injection to make it swell naturally, add 4% sodium hydroxide solution to adjust the pH value to 7.0, and use sodium hyaluronate and trehalose After dissolving in water for injection, add it to the swollen carbomer 940NF and mix evenly to obtain a skin care gel ...

Embodiment 2

[0039] A kind of complex growth factor skin care gel, it comprises the following raw material components by mass percentage:

[0040]

[0041] The active ingredient in the composite growth factor stock solution is rh-bFGF:KGF=1:1. The complex growth factor stock solution includes 0.6% of the active ingredients of the complex growth factor and a balance of 150mmol / L phosphate buffer solution in terms of mass percentage. At the same time, the mass ratio of the heparin sodium to the compound growth factor active ingredient in the compound growth stock solution is 1:1-3.

[0042] Preparation:

[0043] a) Preparation of skin care gel matrix: Weigh carbomer 940NF according to the mass percentage of raw materials, add water for injection to make it swell naturally, add 4% sodium hydroxide solution to adjust the pH value to 7.0, and use sodium hyaluronate and trehalose After dissolving in water for injection, add it to the swollen carbomer 940NF and mix evenly to obtain a skin ca...

Embodiment 3

[0048] A kind of complex growth factor skin care gel, it comprises the following raw material components by mass percentage:

[0049]

[0050] The active ingredient in the composite growth factor stock solution is rh-bFGF:KGF=1:1. The complex growth factor stock solution includes 0.3% of the active ingredients of the complex growth factor and the balance of 150mmol / L phosphate buffer solution in terms of mass percentage. At the same time, the mass ratio of the heparin sodium to the compound growth factor active ingredient in the compound growth stock solution is 1:1-3.

[0051] Preparation:

[0052] a) Preparation of skin care gel matrix: Weigh carbomer 940NF according to the mass percentage of raw materials, add water for injection to make it swell naturally, add 4% sodium hydroxide solution to adjust the pH value to 7.0, and use sodium hyaluronate and trehalose After dissolving in water for injection, add it to the swollen carbomer 940NF and mix evenly to obtain a skin ...

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Abstract

The invention discloses composite growth factor skincare gel. The composite growth factor skincare gel is prepared from, by mass, 1-50% of composite growth factor stock solution, 0.5-1.5% of carbomer 940NF, 1-10% of 4% sodium hydroxide solution, 0.1-2% of sodium hyaluronate, 0.1-10% of trehalose, 1-10% of mannitol, 0.85-0.95% of sodium chloride, 0.1-5% of dextranum 40, 0.00003-0.3% of heparin sodium and the balance injection water. Rh-bFGF and KGF in the composite growth factor stock solution are compounded according to a specific proportion and used for a skincare gel formula; on the basis of moisture preservation, skin redness and swelling can be effectively relieved, and skin wounds and scars can be effectively restored; skin is prevented from bearing toxic irritation of other skincare products, and the composite growth factor skincare gel mainly aims at people suffering from severe skin aging, skin redness and swelling and skin local wounds or breakage, such as hormone face patients for long-term skincare.

Description

technical field [0001] The invention relates to the field of skin care products, in particular to a skin care gel and a preparation method thereof. Background technique [0002] With the continuous progress of the social economy and the enrichment of material life, skin care products are no longer something that only rich people can afford in the past, and now skin care products have entered the homes of ordinary people. There are many types of skin care products with different characteristics. The ingredients and functions of each skin care product vary according to different skin properties. At the same time, due to the emergence of various inferior cosmetics and skin care products on the market, some middle-aged and elderly people have used such inferior products for a long time, resulting in more skin problems and even skin diseases, such as accelerated skin aging, dry and itchy skin, pigmentation, Clogged pores, red and swollen skin, hormonal face, etc. Therefore, the ...

Claims

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Application Information

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IPC IPC(8): A61K8/64A61K8/04A61Q19/00A61Q19/08
CPCA61K8/64A61K8/042A61K2800/5922A61Q19/00A61Q19/005A61Q19/08
Inventor 付廷灵张元方欧智慧
Owner 朗肽生物制药股份有限公司
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