SD rat production method

A production method and technology for female rats, applied in the direction of animal feed, additional food elements, animal feed, etc., can solve the problems of difficulty in estrus, accumulation of fat in rats, affecting fertility, etc., to maintain nutritional needs, enhance physical fitness, and improve reproduction. Efficiency and effect on pup quality

Active Publication Date: 2016-11-09
SPF BEIJING LAB ANIMAL SCI & TECH CO LTD
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Problems solved by technology

However, too much protein, fat or carbohydrates will cause fat accumulation in mice, and fatty...

Method used

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  • SD rat production method

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Embodiment 1

[0028] A total of 100 healthy female and male mice were reared in a barrier environment, including 80 female mice, all over 90 days old, weighing between 216 and 225g, with an average weight of 219.8g; 20 male mice, all 85 days old Above, the weight is between 290~310g, and the average weight is 301.6g.

[0029] The parental female and male mice should be healthy and disease-free, with thick and shiny coat and close to the body; bright eyes, normal breathing, quick and powerful limb movements, no tail loss, well-proportioned body shape, broad head, and neck Moderate length, broad and straight back, well laced belly. The male testicles were normally developed and the magnetic nipples were prominent.

[0030] Feeding environment for female and male mice: temperature 23~25℃, relative humidity 45~55%, noise below 85 decibels, ammonia concentration below 20ppm, ventilation 18~20 times per hour, light conditions: 12 hours of light and 12 hours of darkness alternately.

[0031] Bo...

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Abstract

The invention discloses an SD rat production method. The first round of mating of female rats and male rats is conducted according to the ratio of 1:2, female rats and male rats are raised separately after female rats get pregnant, and pregnant female rats mate with male rats for the second round according to the ratio of 1:2 1-2 days after giving birth; female rats and male rats are raised separately after female rats get pregnant, and pregnant female rats mate with male rats for the third round according to the ratio of 1:2 1-2 days after giving birth; this is repeated till female rats are replaced. Female rats are fed with 60Co irradiated and sterilized breeding fodder and drink freely. The breeding fodder comprises crude protein, crude fat, crude fiber, crude ash, calcium, phosphorus, N-carbamylglutamate, lysine, methionine, cystine, vitamin, water and the balance glucose. By improving the rotation mating method, adopting the mating mode that the number of male rats is larger than that of female rats, and using the breeding fodder, SD rat reproduction efficiency and newborn rat quality can be improved remarkably.

Description

technical field [0001] The invention relates to the technical field of experimental animal production, in particular to a production method of SD rats. Background technique [0002] As the most commonly used experimental animals, rats and mice have been widely used in various basic research and application fields such as medicine, pharmacy, biology, veterinary medicine, embryology, and genetics. In biomedical animal experiments, its utilization rate is as high as about 80%. [0003] In the production of standardized experimental rats and mice, in addition to microbiology, genetics, and environmental control, the supply of feed with a scientific ratio of nutrients is a key condition for maintaining animal health and improving the quality of animal experiments. With the development of science and technology, the requirements for the quantity and quality of rats and mice have gradually increased, and the quality of experimental animal feed has entered the national standardized...

Claims

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Application Information

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IPC IPC(8): A01K67/02A23K50/50A23K20/10A23K20/174A23K20/20A23K10/30A23K20/147
CPCA01K67/02
Inventor 展德文战大伟王亮
Owner SPF BEIJING LAB ANIMAL SCI & TECH CO LTD
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