Preparation method of ferrous glycine sulfate complex

Abstract

The invention provides a preparation method of a ferrous glycine sulfate complex. The preparation method comprises the following steps: dissolving glycine and ferrous sulfate into water, adding a small amount of iron powder and multiple drops of concentrated sulfuric acid, carrying out rotation reaction at 70-90 DEG C, cooling to 50-65 DEG C to crystallize, then carrying out suction filtration to obtain crystalline solids, washing the crystalline solids for several times with absolute ethyl alcohol, and carrying out natural airing, so as to obtain the ferrous glycine sulfate complex. The crystallization temperature in the preparation method is 50-65 DEG C and is 25 DEG C higher than that of an existing method, so that the time of the cooling crystallization process is shortened, and the energy consumption in the refrigeration cooling process is reduced; and meanwhile, the yield of the ferrous glycine sulfate complex prepared by virtue of the method is high, the product contains a small amount of crystal water, and the energy consumption in the subsequent drying process of the product is low.

Description

technical field [0001] The invention relates to a preparation method of a compound, in particular to a preparation method of a ferrous glycinate complex. Background technique [0002] Ferrous glycine complex has high biological effects, and is relatively close to the trace element supplement of natural form in animals. Studies have shown that even with the same inhibitors, the absorption of ferrous amino acid is 4.5 times higher than that of ferrous sulfate. This excellent bioavailability makes it a third-generation new compound amino acid iron chelate in iron nutritional supplements. It can even be completely absorbed and utilized by animals, and has good chemical stability. It not only avoids the mutual antagonism between minerals, but also eliminates the disadvantages of vitamin oxidation by inorganic salts. There are almost no gastrointestinal side effects commonly caused by iron supplements, such as constipation and stomach upset, and there are no adverse dietary inte...

AI Technical Summary

Problems solved by technology

Mainly include: metathesis method, direct coordination method, solid-phase method at room temperature, etc., but the ratio is mostly glycine: ferrous sulfate heptahydrate is 2:1; there are few reports about the synthesis ratio of 1:1

Moreover, the yield of ferrous glycinate complex crystallized at normal temperature is relatively high, but the amount of crystal water contained in the synthesized product is large, which is not conducive to production and storage, and the energy consumption of subsequent drying of the product is high.

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