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Preparation method and application of compound astragalus polysaccharide injection

A technology for the preparation of injections and astragalus polysaccharides, which is applied in the field of preparation of compound astragalus polysaccharide injections, can solve the problems of high mortality and poor control effects of single drugs

Inactive Publication Date: 2017-01-04
株洲市神农动物药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Many experts began to treat this disease as toxoplasmosis and eperythrozoonosis, and then simply treated it as blue ear disease, influenza, and swine fever. The control effect is extremely poor, resulting in high mortality rate, which once caused panic among farmers. Therefore, the development of a compound preparation that can inhibit the replication of various viruses, activate the body's immune system, and improve the body's immune response level is not only the development of animal husbandry. necessary and imperative

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A preparation method and application of compound astragalus polysaccharide injection, the steps are as follows:

[0018] First, weigh 1 kg of astragalus polysaccharide and add it to a stirring device to dissolve it, then filter it after overnight, then weigh 30 g of double-stranded polymyocytes and add it to a stirring device to dissolve, take a small amount of water for injection, and then weigh the ground Add 50 g of dexamethasone sodium phosphate into the stirring device for stirring and dissolving, then take a small amount of water for injection, weigh 10 kg of analgin and 1 kg of inosine and add it to the knife stirring device for stirring and dissolving, continue to take a small amount of water for injection, add anhydrous sub Add 70g of sodium bisulfate and 7g of disodium ethylenediaminetetraacetate into the mixing tank for dissolving and mixing. At the same time, add 10,000ml of ethanol and 300g of activated carbon and stir evenly. After standing for decolorizati...

Embodiment 2

[0020] A preparation method and application of compound astragalus polysaccharide injection, the steps are as follows:

[0021] First, weigh 1.5kg of astragalus polysaccharide and add it to the stirring device to dissolve it, and then filter it after overnight, then weigh 70g of double-stranded polymyocytes and add it to the stirring device to dissolve, take a small amount of water for injection, and then weigh Add 75g of dexamethasone sodium phosphate into the stirring device for stirring and dissolving, then take a small amount of water for injection, weigh 20 kg of Analgin and 1.5 kg of inosine and add it into the knife stirring device for stirring and dissolving, continue to take a small amount of water for injection, add Add 85g of sodium bisulfite and 8.5g of disodium ethylenediaminetetraacetate into the mixing tank for dissolving and mixing. At the same time, add 15000ml of ethanol and 400g of activated carbon and stir evenly. After standing for decolorization, filter, a...

Embodiment 3

[0023] A preparation method and application of compound astragalus polysaccharide injection, the steps are as follows:

[0024] First, weigh 2 kg of astragalus polysaccharide and add it to a stirring device to dissolve it, then filter it after overnight, then weigh 100 g of double-stranded polymyocytes and add it to a stirring device to dissolve, take a small amount of water for injection, and then weigh the ground Add 100 g of dexamethasone sodium phosphate into the stirring device for stirring and dissolving, then take a small amount of water for injection, weigh 30 kg of analgin and 2 kg of inosine and add it into the knife stirring device for stirring and dissolving, continue to take a small amount of water for injection, add anhydrous sub Add 100g of sodium bisulfate and 10g of disodium ethylenediaminetetraacetate into the mixing tank for dissolving and mixing. At the same time, add 20,000ml of ethanol and 500g of activated carbon and stir evenly. After standing for decolo...

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PUM

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Abstract

The invention discloses preparation method and application of a compound astragalus polysaccharide injection. The compound astragalus polysaccharide injection is characterized by comprising the following components: 1-2 kg of astragalus polysaccharide, 30-100 g of double-stranded polyinosinic cell, 10-30 kg of analginum, 50-100 kg of dexamethasone sodium phosphate, 1-2 kg of inosine, 10000-20000 ml of ethyl alcohol, 7-10 g of ethylene diamine tetraacetic acid disodium, 70-100 g of anhydrous sodium sulfite, 300-500 g of activated carbon and the balance of water. The preparation method and the application of the compound astragalus polysaccharide injection, disclosed by the invention, have the advantages that the immunological competence is improved, the weights of immune organs are increased, and the immunosuppression caused by cyclophosphamide can be converted to a normal level; a body can also be stimulated to generate a non-specific antibody; a skin vessel is expanded, the blood flow is accelerated, the heat radiation is accelerated to reduce the body temperature; the efficacies of allergy resistance, temperature reduction, quick recovery of the appetite of sick livestock and poultry and the like are achieved; the drugs are reasonably prepared, the etiological and symptomatic treatment is simultaneously performed aiming at viral infection, the virus replication is restrained, the body immunity is improved, the vaccine response level is improved, the clinical symptoms are relieved, and the quick recovery of the sick livestock and poultry is promoted.

Description

technical field [0001] The invention relates to the technical field of biomedicine manufacturing, in particular to a preparation method and application of compound astragalus polysaccharide injection. Background technique [0002] In recent years, in order to ensure human health, most antiviral drugs commonly used in veterinary medicine, such as morpholino, ribavirin, and amantadine, have been banned, and broad-spectrum antiviral drugs have reached the point where no drugs are available. At the same time, many pig farms and free-range farmers from south to north broke out a strange disease characterized by high fever, rapid infection, loss of appetite or even extinction, and high mortality. The Ministry organized relevant experts to diagnose and analyze on-site, and diagnosed it as unknown high fever in pigs caused by mixed infection of various viruses, bacteria, and mycoplasma (including Mycoplasma pneumoniae, Eperythrozoon) Toxoplasma. Among them, the highly pathogenic PR...

Claims

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Application Information

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IPC IPC(8): A61K33/44A61K33/04A61K31/80A61K31/708A61K31/7012A61K31/7004A61K31/573A61K31/4152A61K31/198A61K31/045A61K9/08A61P31/12A61P37/04
CPCA61K33/44A61K9/0019A61K9/08A61K31/045A61K31/198A61K31/4152A61K31/573A61K31/7004A61K31/7012A61K31/708A61K31/80A61K33/04A61K47/183A61K2300/00
Inventor 成青兰胡春灿成劲彭静波
Owner 株洲市神农动物药业有限公司
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