Traditional Chinese medicine granule for treating diffuse interstitial pulmonary fibrosis lung and kidney qi insufficiency syndrome

A technology for pulmonary interstitial fibrosis and lung and kidney qi deficiency, which is applied in the field of medicine, can solve the problems of low research quality, and achieve the effect of scientific preparation method and abundant raw materials

Active Publication Date: 2017-01-11
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

It is worth noting that there are few high-quality clinical reports at present, the quality of generalized rese...

Method used

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  • Traditional Chinese medicine granule for treating diffuse interstitial pulmonary fibrosis lung and kidney qi insufficiency syndrome
  • Traditional Chinese medicine granule for treating diffuse interstitial pulmonary fibrosis lung and kidney qi insufficiency syndrome
  • Traditional Chinese medicine granule for treating diffuse interstitial pulmonary fibrosis lung and kidney qi insufficiency syndrome

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Experimental program
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Effect test

Embodiment 1

[0014] In the specific implementation of the present invention, the traditional Chinese medicine granules of the present invention are composed of 6g of ginseng, 6g of Radix Ophiopogon, 10g of Rehmannia glutinosa, 10g of Trichosanthes mellifera, 6g of Fritillaria, 9g of Cortex Moutan, 6g of Epimedium, 5g of Ginkgo, 6g of Pulsatilla, 10g of Coix Seed Made with dried tangerine peel 6g; wherein, ginseng is pulverized into superfine powder (crossing a 150 mesh sieve) to obtain ginseng superfine powder A, which is for subsequent use; dried tangerine peel is added to 6 times the weight of dried tangerine peel and distilled for 5 hours to collect volatile oil and dregs of tangerine peel Standby, the volatile oil is ground and clathrated with β-cyclodextrin of 8 times the weight of the volatile oil, dried under reduced pressure, and pulverized into fine powder (passing through a 80 mesh sieve) to obtain β-cyclodextrin inclusion compound B, which is set aside; The slag is combined with ...

Embodiment 2

[0016] In the specific implementation of the present invention, the traditional Chinese medicine granules of the present invention are composed of 9g of ginseng, 12g of Ophiopogon japonicus, 12g of Rehmannia glutinosa, 15g of Trichosanthes fritillata, 9g of fritillary fritillaria, 12g of Moutan cortex, 9g of epimedium, 9g of ginkgo, 9g of pulsatilla, 15g of coix seed Made with dried tangerine peel 12g; wherein, ginseng is pulverized into superfine powder (crossing a 150 mesh sieve) to obtain ginseng superfine powder A, for subsequent use; dried tangerine peel is added to 6 times the weight of dried tangerine peel and distilled for 5 hours to collect volatile oil, dried tangerine peel dregs Standby, the volatile oil is ground and clathrated with β-cyclodextrin of 8 times the weight of the volatile oil, dried under reduced pressure, and pulverized into fine powder (passing through a 80 mesh sieve) to obtain β-cyclodextrin inclusion compound B, which is set aside; The slag is comb...

Embodiment 3

[0018]In the specific implementation of the present invention, the traditional Chinese medicine granules of the present invention are composed of 9g of ginseng, 10g of Ophiopogon japonicus, 15g of rehmannia glutinosa, 15g of Trichosanthes mellifera, 9g of fritillary fritillaria, 12g of Moutan cortex, 10g of epimedium, 8g of ginkgo, 10g of pulsatilla, 15g of coix seed Made with dried tangerine peel 10g; Wherein, ginseng is pulverized into superfine powder (passes through 150 mesh sieves), obtains ginseng superfine powder A, for subsequent use; Add tangerine peel to 6 times the water distillation of tangerine peel weight for 5 hours, collect volatile oil, tangerine peel dregs Standby, the volatile oil is ground and clathrated with β-cyclodextrin of 8 times the weight of the volatile oil, dried under reduced pressure, and pulverized into fine powder (passing through a 80 mesh sieve) to obtain β-cyclodextrin inclusion compound B, which is set aside; The slag is combined with Fritil...

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Abstract

The invention relates to a traditional Chinese medicine granule for treating diffuse interstitial pulmonary fibrosis lung and kidney qi insufficiency syndrome, and can effectively solve the problem of medication in later period treatment of the diffuse interstitial pulmonary fibrosis. In order to solve the problems, the traditional Chinese medicine granule has the technical scheme that ginseng is crushed to obtain ultrafine ginseng powder A; dried orange peel is subjected to water vapor distillation volatile oil extraction; beta-cyclodextrin inclusion compounds B are prepared; the dried orange peel medicine dregs, thunberg fritillary bulb, cortex moutan, epimedium and ginkgo biloba are merged; the mixture is subjected to reflux extraction by 70-percent ethanol to obtain first extract paste; the mixed medicine dregs of the dried orange peel, the thunberg fritillary bulb, the cortex moutan, the epimedium and the ginkgo are decorated and boiled by water to obtain first filter liquid; dwarf lilyturf roots, prepared rehmannia roots, trichosanthes kirilowii Maxim, Chinese pulsatilla roots and coix seeds are decorated and boiled by water to obtain second filter liquid; the first filter liquid and the second filter liquid are merged to obtain second extract paste; the first extract paste and the second extract paste are merged to prepare extract paste fine powder C; ginseng ultrafine powder A, the beta-cyclodextrin inclusion compounds B and the extract paste fine powder C are merged; uniform mixing, pelletization and drying are performed; the traditional Chinese medicine granule is obtained. The traditional Chinese medicine granule has the advantages that the matching is reasonable; the method is scientific; the curative effect is exact and economic; the social benefits are obvious.

Description

[0001] 1. Technical field [0002] The invention relates to medicine, in particular to traditional Chinese medicine granules (also known as Jinshui Huanxian Fang, the same below) for treating diffuse pulmonary fibrosis with deficiency of lung and kidney qi. [0003] 2. Background technology [0004] Diffuse pulmonary fibrosis is a serious and difficult disease with great harm. It has the characteristics of high morbidity, high mortality, high disability rate, and heavy disease burden, which seriously endangers the health and quality of life of patients. Diffuse interstitial lung disease is a group of non-neoplastic and non-infectious disease groups that mainly include the alveolar wall and surrounding tissue and its adjacent supporting structures, the most representative of which is idiopathic pulmonary interstitial fibrosis (idiopathic pulmonary disease, IPF). IPF is a chronic progressive interstitial lung disease of unknown etiology, characterized by progressive dyspnea and ...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61K9/16A61P11/00
CPCA61K9/1652A61K36/16A61K36/258A61K36/296A61K36/428A61K36/65A61K36/71A61K36/752A61K36/804A61K36/8966A61K36/8968A61K36/8994A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 李建生李亚任周新冯素香李萌白云萍
Owner HENAN UNIV OF CHINESE MEDICINE
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