Application of high-strength acryloyl-glycinamide-based hydrogel as thermoplastic polymer
A technology of acryloyl glycinamide and thermoplastic polymers, applied in medical science, prostheses, etc., can solve the problems of high tensile and compression resistance, and achieve good biocompatibility, good mechanical strength and toughness Effect
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[0022] The technical solutions of the present invention will be further described below in conjunction with specific embodiments.
[0023] In the examples, glycinamide hydrochloride and acryloyl chloride were used as raw materials according to references (Boustta M, Colombo P E, Lenglet S, et al. Versatile UCST-based thermoresponsive hydrogels for loco-regional sustained drug delivery [J]. Journal of Controlled Release, 2014,174:1-6) prepared a monomer acryloyl glycinamide with two amide groups, the chemical formula structure is shown in the following chemical formula:
[0024]
[0025] Utilize Fourier transform infrared spectroscopy (U.S. Platinum Elmer Company) to prove its successful synthesis, wherein their characteristic peaks are as follows: ν=3389cm -1 (m,NH),3314cm -1 (s,NH),3191cm -1 (m,NH),1662cm -1 (vs, C=O), 1626cm -1 (vs, C=O), 1556cm -1 (vs, NH) (see attached figure 1 ).
[0026] Carry out homopolymerization with the acryloyl glycinamide synthesized abo...
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