Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of combination of heat-clearing traditional Chinese medicinal composition and antibiotic in preparation of uterus disease treatment drugs

A composition and antibiotic technology, applied in the field of medicine, can solve the problems of traditional Chinese medicine composition and azithromycin, etc., and achieve good edema, improve uterine hyperemia, hyperplasia and hypertrophy

Inactive Publication Date: 2017-02-22
ZHUZHOU QIANJIN PHARMA
View PDF1 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there is no relevant technical report on the combination of traditional Chinese medicine composition and azithromycin for the preparation of drugs for the treatment of uterine diseases

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of combination of heat-clearing traditional Chinese medicinal composition and antibiotic in preparation of uterus disease treatment drugs
  • Application of combination of heat-clearing traditional Chinese medicinal composition and antibiotic in preparation of uterus disease treatment drugs
  • Application of combination of heat-clearing traditional Chinese medicinal composition and antibiotic in preparation of uterus disease treatment drugs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] 1. Experimental strains: Staphylococcus aureus (ATCC25923), Escherichia coli (ATCC25922)

[0020] Bought from China National Culture Bank. Suspend the lyophilized powder of the tested strains in sterile M-H(B) medium and spread evenly on the surface of the sterile M-H(A) plate, incubate overnight at 35°C for revival, after 18 hours a lawn grows on the surface of the plate, select the ones with good growth Single bacterial mass, re-smear on the M-H(A) slant, incubate under the same conditions for 18h, seal, and store in refrigerator at 4°C; the day before the test, take the slant bacteria and smear it on the M-H(A) plate, incubate overnight at 35°C, ready to use . All operations are done on a clean bench.

[0021] 2. Bacteria solution preparation method

[0022] Method 1: (preparation of high-concentration bacterial solution)

[0023] Pick 3-4 single colonies in 40 ml of M-H(B) medium. The test bacteria were enriched and cultured overnight for 16 hours (37°C, shaken...

Embodiment 2

[0054] Embodiment 2 application example

[0055] 1. Research object: Choose outpatient volunteers from March 2015 to February 2016, 30 patients aged 35-50 who were pathologically diagnosed with endometrial hyperplasia due to irregular vaginal bleeding, menorrhagia, and dysmenorrhea due to dilatation and curettage aged, 27 cases of simple hyperplasia, 3 cases of complex hyperplasia, 5 cases of dysmenorrhea, and 10 cases of enlarged uterus.

[0056] 2. Methods: All patients were routinely checked for blood routine, liver and kidney function, follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2) and progesterone (P) before treatment, and B-ultrasound Check and measure uterine size and endometrial thickness. On the 5th day after curettage, Chinese medicine composition of the present invention (prepared composition, decoction or tablet with Qianjinba, Andrographis paniculata, Rosa root, Gonglaomu, and single-faced needle with reference to the formula ratio a...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an application of a combination of a heat-clearing traditional Chinese medicinal composition and an antibiotic in the preparation of uterus disease treatment drugs, and especially an application in the preparation of uterine hyperemia edema and hypertrophy treatment and improvement drugs. The antibiotic is azithromycin. The active components of the heat-clearing traditional Chinese medicinal composition comprise Philippine flemingia root, Andrographis paniculata, Root of Cherokee Rose, Stem of Chinese Mahonia and Zanthoxylum dissitum Hemsl. The combination of the heat-clearing traditional Chinese medicinal composition and the antibiotic has a good targeting application in improvement of uterus hyperemia, edema and hyperplasia, and is same to a combination of Fukeqianjin Tablets and azithromycin in reduction of the thymus organ index.

Description

technical field [0001] The invention relates to the technical field of medicine, and more specifically, relates to the application of a heat-clearing traditional Chinese medicine composition combined with antibiotics in the preparation of medicines for treating uterine diseases. [0002] technical background [0003] Metritis is one of the pelvic genital inflammations. It is a common disease in women. The inflammation can be limited to one part or several parts at the same time. Clinically, the latter case is more common. Acute inflammation may cause diffuse peritonitis, Serious consequences such as sepsis and septic shock; uterine edema is generally caused by acute inflammation, which will lead to excessive menstrual flow, and if not treated in time, it may lead to chronic uterine hypertrophy, etc. Uterine hypertrophy refers to the uniform enlargement of the uterus, the basic pathological Changes are changes in smooth muscle cells and blood vessel walls in the myometrium. T...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/758A61K31/7052A61P15/00
CPCA61K36/48A61K31/7052A61K36/19A61K36/29A61K36/738A61K36/758A61K2300/00
Inventor 张鹏李伏君邹亮龚云伍实花
Owner ZHUZHOU QIANJIN PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com