33 results about "Treat to target" patented technology

The invention discloses a pharmaceutical composition for treating diabetes and its preparation method and application. The pharmaceutical composition comprises the following raw materials in parts by weight: 3-5 parts of astragalus, 2-2.5 parts of salvia miltiorrhiza, 1-2 parts of rehmannia glutinosa, 2-3 parts of bitter gourd, 1-2 parts of polygonatum, 2-3 parts of coptis, 0.5-1 part of Atractylodes macrocephala, 0.8-1.5 parts of Polygonatum, 0.5-1 part of Scutellaria baicalensis, 2-3 parts of trichosanthin, 1.5-3 parts of raw gypsum, mulberry 2‑3.5 parts of root, 2‑3.5 parts of dendrobium, 2‑4 parts of Chinese yam, 1‑2 parts of capillary, 2 parts of cash cow leaves, 1‑2 parts of cinnamon bark, 2‑3 parts of black tea, 3‑5 parts of dried potatoes, 1.5-2 parts of grape seeds, 1-1.5 parts of cheese, 2-3 parts of wheat bran, 2-2.5 parts of seaweed. The pharmaceutical composition of the present invention can control complications by invigorating the kidney and increasing resistance, activating collaterals and invigorating the heart, reducing blood pressure and removing fat; balancing body constitution by balancing cold and heat, unblocking the middle and harmonizing the body, nourishing qi and nourishing blood; , Improving insulin sensitivity to carry out targeted therapy to repair islet function; it can effectively treat diabetes, and the curative effect is significant.

The invention discloses a medicinal composition used for treating or preventing cerebrovascular disease and related diseases. The composition comprises the following components in parts by weight: 1-50 parts of DHA (docosahexaenoic acid), 1-50 parts ofbreviscapine, 20-50 parts of and 1-10 parts of hirudin. The composition also comprises effective amount of human fat stem cell which is taken as a carrier for the medicinal composition, thus treatment medicine smoothly penetrates through a blood brain barrier, and the effect of targeted treatment on the cerebrovascular disease and related diseases is achieved. The medicinal composition disclosed by the invention can effectively improve diseases such as attack, infarction and embolism which are caused by ischemia of the brain, can effectively inhibit thrombus from being formed in human body and has good curative effect on senile dementia caused by the cerebrovascular disease, namely presenile dementia.

The invention discloses a traditional Chinese medicine composition for hyperplasia of mammary glands and a preparation method of a hydrogel patch thereof. The traditional Chinese medicine composition comprises figwort root, tangerine seed, lychee seed, diverse wormwood herb, Indian iphigenia bulb, honeylocust, rhizoma corydalis, seaweed, flos caryophyllata and garden balsam, and a pharmaceutical extract of the traditional Chinese medicine composition is obtained by extraction. The preparation method of the hydrogel patch of the traditional Chinese medicine composition for the hyperplasia of the mammary glands comprises the following steps: using a framework material, a tackifier, a humectant, a preservative, a filler, a crosslinking agent, a crosslinking regulator, a pH regulator, the pharmaceutical extract and distilled water to prepare a medicine-loaded hydrogen patch matrix; and then performing coating, cutting, standing and other steps, thus obtaining the hydrogel patch. The traditional Chinese medicine composition has a target treatment role of directly delivering the pharmaceutical active ingredients to tissues with hyperplasia lesion of the mammary glands, has the long-acting sustained-release role for sustained release of the pharmaceutical active ingredients for a long time, is convenient and comfortable to use and has the advantages of no skin irritation, no allergy and the like, thereby being an ideal pharmaceutical preparation for treating the hyperplasia of the mammary glands.

The present invention is related to novel cytotoxic agents, pyrrolo[2,1-c][1,4]benzodiazepine (PBD) derivatives, their conjugates with a cell-binding agent, the preparation and the therapeutic uses in the targeted treatment of cancers, autoimmune disorders, and infectious diseases.

A biocompatible polymer to which a plurality of clot-modulating peptides (CMPs) are bound. The polymer comprises repeating units of hydrophilic monomers and display monomers to which the CMPs are bound. For example, the CMPs can be fibrin binding peptides (FBPs) that enhance clot formation by cross-linking that occurs within and between fibers by the plurality of fibrin-binding peptides during fibrin polymerization. The polymers of the invention can be used to modulate clotting in a variety of ways via multivalent display of fibrin-binding peptides and other clot-binding and clot-modulating moieties on polymer or co-polymer backbones. In addition to clot-modulating moieties, imaging agents and therapeutic agents can be conjugated to the polymers to facilitate imaging of blood flow and thrombosis, and for treatment of clotting-related disorders.

The invention discloses a Chinese medicine pill for treating esophageal cancer and a process technology. By mainly aiming at the disadvantages of modern technologies, treatment focusing on relieving both secondary and primary symptoms, strengthening the body resistance and eliminating evil and fixed-point targeted medicine use are adopted so that not only the immunity of the organism is improved, but the treatment effect for suppressing growth of cancer cells is also realized. The Chinese medicine pill for treating esophageal cancer is characterized by consisting of rhizoma paridis, blackberrylily rhizome, American ginseng, radix astragali, poria cocos, purple sal ammoniac, podophyllum hexandrum, ruddle, bear bile, calculus bovis factitius, menthol crystal, barium sulfate, colla asini and the like. Two double-layer pills for fixed-point targeted treatment are produced by applying a layered pill production technology and a clinical mechanics principle. The first pills are generally taken in morning and mainly used for opening the esophagus to guarantee food nutrition intake. The second pills are generally taken in evening to be remained at a lesion position and mainly used for killing cancer cells directionally to play the role in suppressing tumor growth and relieving pain as well as swelling.