The invention discloses a clock signal loss detecting circuit and a clock signal loss detecting method. The circuit comprises a frequency dividing module, a counting module, a displacing module, a comparing module and a detecting module. The method utilizes a low-frequency clock to detect a high-frequency and includes five steps to realize a process: dividing frequencies, counting, displacing, comparing and detecting. The clock signal loss detecting circuit and the clock signal loss detecting method have the advantages that by means of detecting whether clock signals lose or not, normal operation of an integrated circuit system can be guaranteed, logical resources are saved, and overall performance of the integrated circuit system is improved. Besides, a universal solution to the design of an application specific integrated circuit multiplexed by an IP (intellectual property) module is provided, so that time for developing products is shortened, and design cost is reduced.