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A traditional Chinese medicine composition and its application in the preparation of medicines for treating skin damage after radiotherapy and chemotherapy

A technology for skin damage and composition, which is applied in the field of traditional Chinese medicine, can solve problems such as inability to apply skin damage, and achieve non-toxic and side effects, quick effect, and good therapeutic effect

Active Publication Date: 2018-01-23
YANGZIJIANG PHARMA GROUP SHANGHAI HAINI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the limitation of the component content of the composition and the extraction method, the composition cannot be applied to the skin damage of cancer patients after radiotherapy and chemotherapy

Method used

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  • A traditional Chinese medicine composition and its application in the preparation of medicines for treating skin damage after radiotherapy and chemotherapy
  • A traditional Chinese medicine composition and its application in the preparation of medicines for treating skin damage after radiotherapy and chemotherapy
  • A traditional Chinese medicine composition and its application in the preparation of medicines for treating skin damage after radiotherapy and chemotherapy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] A kind of traditional Chinese medicine composition, is made of the raw material drug of following parts by weight:

[0043]

[0044] According to the proportioning of above-mentioned Chinese medicine composition, make following preparation:

[0045] (1) Grind Coptis rhizoma into the coarsest powder, extract with water reflux, concentrate the filtrate to a relative density of 1.15 at 60°C, add ethanol until the ethanol concentration is 60%, stir well, keep silent overnight, suction filter, and recover the ethanol from the filtrate until it is alcohol-free flavor, continue to concentrate until the relative density is 1.35 at 60°C, dry, and pulverize to obtain Coptis chinensis extract powder, which is set aside;

[0046] (2) Reflux extracting Comfrey and Radix Radix with ethanol, filter, and retain the dregs of the medicine; the filtrate recovers ethanol until it has no alcohol smell, dries, and pulverizes to obtain Comfrey Radix Radix and Radix Radix Extract Powder, whic...

Embodiment 2

[0057] A kind of traditional Chinese medicine composition, is made of the raw material drug of following parts by weight:

[0058]

[0059]

[0060] (1) Grind Coptidis rhizoma into the coarsest powder, extract with water reflux, concentrate the filtrate to a relative density of 1.10 at 60°C, add ethanol until the concentration of ethanol is 55%, stir well, keep silent overnight, filter with suction, and recover the ethanol from the filtrate until it is alcohol-free flavor, continue to concentrate until the relative density is 1.30 at 60°C, dry, and pulverize to obtain Coptis chinensis extract powder, which is set aside;

[0061] (2) Reflux extracting Comfrey and Radix Radix with ethanol, filter, and retain the dregs of the medicine; the filtrate recovers ethanol until it has no alcohol smell, dries, and pulverizes to obtain Comfrey Radix Radix and Radix Radix Extract Powder, which is set aside;

[0062] (3) Grind the root of asarum into the coarsest powder, reflux the wa...

Embodiment 3

[0072] A kind of traditional Chinese medicine composition, is made of the raw material drug of following parts by weight:

[0073]

[0074] (1) Grind Coptis rhizoma into the coarsest powder, extract with water reflux, concentrate the filtrate to a relative density of 1.20 at 60°C, add ethanol until the concentration of ethanol is 65%, stir well, keep silent overnight, filter with suction, and recover the ethanol from the filtrate until it is alcohol-free flavor, continue to concentrate to a relative density of 1.40 at 60°C, dry, and pulverize to obtain Coptis chinensis extract powder, which is set aside;

[0075] (2) Reflux extracting Comfrey and Radix Radix with ethanol, filter, and retain the dregs of the medicine; the filtrate recovers ethanol until it has no alcohol smell, dries, and pulverizes to obtain Comfrey Radix Radix and Radix Radix Extract Powder, which is set aside;

[0076] (3) Grind the root of asarum into the coarsest powder, reflux the water to extract and ...

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Abstract

The invention belongs to the field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicinal composition. The traditional Chinese medicinal composition is prepared from the following raw medicines in parts by weight: 800 to 850 parts of rhizoma coptidis, 475 to 525 parts of herba corydalis bungeanae, 300 to 350 parts of radix isatidis, 300 to 350 parts of radix arnebiae seu lithospermi, 475 to 525 parts of flos lonicerae, 475 to 525 parts of common lophatherum herb, 25 to 50 parts of dried snake gall, 420 to 460 parts of rhizoma rehmanniae, 475 to 525 parts of lily, and 300 to 350 parts of north asarum root. The invention also provides application of the traditional Chinese medicinal composition in the aspect of treating skin injury after radiotherapy and chemotherapy. The traditional Chinese medicinal composition provided by the invention combines a plurality of medicines for use, has the effects of removing rot, promoting tissue regeneration, drawing out toxin and eliminating swelling, can be used for treating the damage of skin mucosa or mouth mucosa after the radiotherapy and the chemotherapy of a cancer patient, is good in treatment effect and quick in response, and does not have a toxic or side effect.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition and its application in treating skin damage after radiotherapy and chemotherapy. Background technique [0002] After radiation therapy or chemotherapy, cancer patients may have erythema, exudate or damage on the skin. With the increase of the cumulative dose, the skin damage will be aggravated, and severe wet reaction may occur to form ulceration. If it is not prevented and treated in time in the early stage, once it forms Ulcers and infections may interfere with radiation or chemotherapy, or even interrupt treatment. In the late stage, there will be prolonged skin ulcers that do not heal, which will bring great pain to the patients. [0003] At present, there are many traditional Chinese medicine preparations or traditional Chinese medicine compositions for treating ulcers or puffs, but there are few medicines s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61K47/69A61P17/02A61P1/02A61P29/00A61K35/583
CPCA61K35/583A61K36/195A61K36/268A61K36/30A61K36/315A61K36/355A61K36/66A61K36/718A61K36/804A61K36/8967A61K36/899A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 朱华荣吴斌郑璐丛海建高苇房莲相石润承刘淑云
Owner YANGZIJIANG PHARMA GROUP SHANGHAI HAINI PHARMA