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absorbent hemostatic sponge

A technology of hemostatic sponge and absorbability, which is applied in the field of absorbable hemostatic sponge, can solve the problems of unsatisfactory biocompatibility of absorbable hemostatic materials, and achieve the effect of improving hemolysis, stable structure, hemolysis and absorption

Active Publication Date: 2019-01-29
JIANGXI TIANHU SPECIAL MEDICAL PROD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Absorbable hemostatic materials are currently a hot spot in the field of surgery. Bleeding and oozing are often encountered in surgery, trauma surgery or war wounds. Compared with traditional methods such as electrocautery, suture, ligation and traditional gauze , the absorbable hemostatic material has the characteristics of little tissue damage, easy operation, rapid hemostasis, etc., but the biocompatibility of the absorbable hemostatic material in the prior art is still not ideal

Method used

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Examples

Experimental program
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Effect test

Embodiment 1

[0022] Absorbable hemostatic sponge, the preparation method is:

[0023] (1) Put 55g of gelatin in an enamel pot or a stainless steel pot, add 480ml of distilled water, let stand to make the gelatin absorb water and swell, put the swelled gelatin in a water bath at 60°C to melt, and set aside;

[0024] (2) Put 15-20g tragacanth gum in an enamel pot or a stainless steel pot, add 200ml of distilled water, let it stand still to make the tragacanth gum absorb water and swell, and put the expanded tragacanth gum in a water bath at 70°C to dissolve it. spare;

[0025] (3) Mix the melted gelatin and the melted tragacanth gum evenly, add them into the foaming barrel, then add 100ml of distilled water, 2.5g of hydroxypropyl methylcellulose, and 5.1g of sodium alginate into the foaming barrel , Poria cocos polysaccharide 8.6g, dioctyl sodium sulfosuccinate 4ml, mix and heat up to 80°C, keep for 10 minutes, then cool down to 50°C, keep for 30 minutes, and finally let cool to 29°C;

[0...

Embodiment 2

[0030] Absorbable hemostatic sponge, the preparation method is:

[0031] (1) Put 60g of gelatin in an enamel pot or a stainless steel pot, add 500ml of distilled water, let it stand still to make the gelatin absorb water and swell, put the swelled gelatin in a water bath at 62°C, melt it, and set aside;

[0032] (2) Put 18g of tragacanth gum in an enamel pot or a stainless steel pot, add 220ml of distilled water, let it stand still to make the tragacanth gum absorb water and swell, put the expanded tragacanth gum in a water bath at 72°C to dissolve it, and set aside;

[0033] (3) Mix the melted gelatin and the melted tragacanth gum evenly, add them into the foaming barrel, then add 120ml of distilled water, 3g of hydroxypropyl methylcellulose, 5.5g of sodium alginate, Mix 9.1g of polysaccharides and 5ml of dioctyl sodium sulfosuccinate, heat up to 82°C, keep for 15 minutes, then cool down to 55°C, keep for 35 minutes, and finally let cool to 32°C;

[0034] (4) Place the coole...

Embodiment 3

[0038] Absorbable hemostatic sponge, the preparation method is:

[0039] (1) Put 65g of gelatin in an enamel pot or a stainless steel pot, add 520ml of distilled water, let stand to make the gelatin absorb water and swell, put the swollen gelatin in a water bath at 65°C to melt, and set aside;

[0040] (2) Put 20g of tragacanth gum in an enamel pot or a stainless steel pot, add 250ml of distilled water, let it stand still to make the tragacanth gum absorb water and swell, put the expanded tragacanth gum in a water bath at 75°C to dissolve it, and set aside;

[0041] (3) Mix the melted gelatin and the melted tragacanth gum evenly, add them into the foaming barrel, then add 150ml of distilled water, 3.5g of hydroxypropyl methylcellulose, and 5.9g of sodium alginate into the foaming barrel , Poria cocos polysaccharide 9.6g, dioctyl sodium sulfosuccinate 6ml, mix and heat up to 85°C, keep for 20 minutes, then cool down to 60°C, keep for 40 minutes, and finally let cool to 35°C;

...

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Abstract

The invention discloses absorptive hemostatic sponge. Two colloids of Gelatin and Gummi Tragacanthae are mixed for use, sodium alginate and pachymaran can improve hemolysis in an auxiliary manner, and surfactant-sodium diethylhexyl sulfosuccinate and hydroxypropyl methyl cellulose are combined for use. A prepared sponge product is exquisite, has good hemolysis and absorptivity and can not cause a hematoma.

Description

technical field [0001] The invention relates to an absorbable hemostatic sponge, which belongs to the field of medical products. Background technique [0002] Sponge is a porous material with good water absorption and can be used to clean items. [0003] Absorbable hemostatic materials are currently a hot spot in the field of surgery. Bleeding and oozing are often encountered in surgery, trauma surgery or war wounds. Compared with traditional methods such as electrocautery, suture, ligation and traditional gauze , the absorbable hemostatic material has the characteristics of little tissue damage, easy operation, rapid hemostasis, etc., but the biocompatibility of the absorbable hemostatic material in the prior art is still not ideal. Contents of the invention [0004] The object of the present invention is to provide an absorbable hemostatic sponge. The prepared sponge product is fine and smooth, has good hemolysis and absorbability, and will not produce hematoma. [000...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L24/10A61L24/08A61L24/00C08L89/00C08L5/00C08J9/12
CPCA61L24/001A61L24/0036A61L24/0042A61L24/08A61L24/104A61L2400/04C08J9/12C08J2389/00C08J2405/00C08L89/00C08L2205/025C08L2205/035C08L5/00C08L5/04C08L5/02C08L1/284C08K5/42
Inventor 徐建
Owner JIANGXI TIANHU SPECIAL MEDICAL PROD