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Capsules for lowering blood sugar with mycelial powder of Trichospora bat moth, its preparation method and use

A technology of Trichospora and bat moth, applied in capsule delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problem of no related research on hypoglycemic activity, and achieve excellent hypoglycemic effect.

Active Publication Date: 2019-12-10
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are no relevant studies on its hypoglycemic activity

Method used

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  • Capsules for lowering blood sugar with mycelial powder of Trichospora bat moth, its preparation method and use
  • Capsules for lowering blood sugar with mycelial powder of Trichospora bat moth, its preparation method and use
  • Capsules for lowering blood sugar with mycelial powder of Trichospora bat moth, its preparation method and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] The hypoglycemic capsules of Trichosporum baculata mycelium powder of embodiment 1 are prepared by the following method:

[0028] (1) Weigh 300 g of ginseng and 340 g of schisandra chinensis, add 5 L of ethanol with a mass fraction of 75% after purification and extract twice, each time for 2 hours, filter the extract and discard the dregs, combine the filtrates at -0.065 MPa, 65 Evaporate under reduced pressure at ℃, recover ethanol and concentrate the filtrate to a relative density of 1.30-1.35g / cm 3 (60°C) extract, dried under reduced pressure at -0.085Mpa, 65°C to obtain a dry paste, crushed and passed through a 80-mesh sieve to obtain a dry paste powder;

[0029] (2) Take by weighing 250g Trichosporum mycelia powder, mix evenly with the dry cream powder that step (1) obtains after cleaning, be that the ethanol wetting of 85% is soft material with mass fraction, 16 mesh sieves granules, dried at 55° C., sieved with 14 meshes, and granulated to obtain 0.3 g / granule o...

Embodiment 2

[0031] The hypoglycemic capsule of embodiment 2 is prepared by the following method:

[0032] (1) Preparation of ginseng water extract: crush 300g ginseng into fine powder, add deionized water, the ratio of solid to liquid is 1:60g / ml, heat and extract at 85°C for 3 times, each time for 3 hours, centrifuge at 1500rpm for 10min, filter Finally, the filtrate is concentrated with a multi-stage flash evaporator and freeze-dried to obtain the ginseng water extract;

[0033] (2) Preparation of water extract of Schisandra chinensis: crush 340g of Schisandra chinensis into fine powder, add deionized water, the ratio of solid to liquid is 1:60g / ml, heat and extract at 85°C for 3 times, each time for 3 hours, centrifuge at 1500rpm for 10min, filter Finally, the filtrate was concentrated with a multi-stage flash evaporator, and freeze-dried to obtain the water extract of Schisandra chinensis;

[0034] (3) Preparation of water extract of Trichosporum mycelium powder: immerse 250g of Tric...

Embodiment 3

[0037] The hypoglycemic capsule of embodiment 3 is prepared by the following method:

[0038] (1) Preparation of ginseng water extract: crush 300g ginseng into fine powder, add deionized water, the ratio of solid to liquid is 1:60g / ml, heat and extract at 85°C for 3 times, each time for 3 hours, centrifuge at 1500rpm for 10min, filter Finally, the filtrate is concentrated with a multi-stage flash evaporator and freeze-dried to obtain the ginseng water extract;

[0039] (2) Preparation of water extract of Schisandra chinensis: crush 340g of Schisandra chinensis into fine powder, add deionized water, the ratio of solid to liquid is 1:60g / ml, heat and extract at 85°C for 3 times, each time for 3 hours, centrifuge at 1500rpm for 10min, filter Finally, the filtrate was concentrated with a multi-stage flash evaporator, and freeze-dried to obtain the water extract of Schisandra chinensis;

[0040] (3) Take by weighing 250g Trichosporum mycelium powder, and mix evenly with ginseng wa...

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Abstract

The invention discloses a hirsutella hepiali chen et shen mycelium powder hypoglycemic capsule. The hirsutella hepiali chen et shen mycelium powder hypoglycemic capsule is prepared from the following raw materials by gram: 200 to 300g of irsutella hepiali chen et shen mycelium powder, 270 to 410g of schisandra chinensis and 240 to 360g of ginseng. The invention further provides a preparation method and an application of the hypoglycemic capsule. The hirsutella hepiali chen et shen mycelium powder hypoglycemic capsule has an excellent hypoglycemic effect, is safe and effective, and has no side effects.

Description

technical field [0001] The invention relates to a blood sugar-lowering capsule, in particular to a blood-sugar-lowering capsule made of Trichosporum mycelia powder, a preparation method and application thereof. Background technique [0002] Diabetes mellitus is a metabolic disorder characterized by impaired glucose metabolism induced by defects in insulin secretion and insulin action, resulting in an imbalance in glucose homeostasis. Diabetes is divided into type 1 and type 2 diabetes based on insulin dependence. The main features of II diabetes are the weakened biological effect of insulin-dependent tissues on insulin, also known as "insulin resistance" and the defect of pancreatic beta cells, which leads to fasting and postprandial hyperglycemia in patients. According to statistics, there were nearly 150 million diabetic patients in the world in 2000 (about 20% in my country). With the continuous improvement of people's living standards, the incidence of obesity and diab...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/79A61K36/57A61K36/068A61K9/48A61P3/10
CPCA61K9/1605A61K36/068A61K36/258A61K36/57A61K36/79A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 逯家辉孟庆繁王迪王贞佐程瑛琨刘艳滕乐生谢晶滕利荣
Owner JILIN UNIV
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