Extraction and separation process for rhizoma polygonati

Abstract

The invention relates to an extraction and separation process for rhizoma polygonati. The extraction and separation process comprises the following steps: (1) crushing dried raw rhizoma polygonati into rhizoma polygonati powder; (2) degreasing the crushed rhizoma polygonati powder by virtue of petroleum ether, so as to obtain degreased rhizoma polygonati powder; and (3) carrying out ultrasonic extraction on the degreased rhizoma polygonati powder by virtue of 75% ethanol: (a) concentrating filtrate, purifying the filtrate by virtue of macroporous adsorption resin, and carrying out ethanol gradient elution and concentration, so as to obtain rhizoma polygonati total lignan and rhizoma polygonati total saponin, and (b) carrying out water extraction on medicine residues to form filtrate and filter residues, abandoning the filter residues, concentrating the filtrate, adding ethanol to generate precipitates, collecting the precipitates, and sequentially washing by virtue of ethanol, absolute ethanol, acetone and diethyl ether, so as to obtain coarse rhizoma polygonati polysaccharide. The extraction separation process has the beneficial effects that the industrial production is easily realized, an extract is high in purity and yield and stable in quality and can meet requirements on medicinal development of rhizoma polygonati, the comprehensive utilization of rhizoma polygonati is increased, and the development and utilization values of rhizoma polygonati in the fields of medical treatment and health are increased.

Description

technical field [0001] The invention relates to an extraction process of Chinese herbal medicine, in particular to an extraction and separation process of Polygonatum. Background technique [0002] Polygonatum Polygonatum is a perennial herb of the Liliaceae Polygonatum genus. It is an important traditional Chinese medicine in my country and has a long history of medication. Polygonatum contains polysaccharides, steroidal saponins, lignans and other chemical components, which have a wide range of pharmacological effects such as cardiovascular protection, hypoglycemic and lipid-lowering, neuroprotective, immune regulation, anti-tumor, antibacterial and antiviral. my country's sealwort is rich in resources, because of its medicinal, edible, ornamental and cosmetic value, the market demand is increasing day by day, it has good economic benefits, and the market prospect is very broad. However, the current extraction process of Polygonatum active ingredients mainly focuses on po...

AI Technical Summary

Problems solved by technology

However, the current extraction process of the effective components of Polygonatum is mainly concentrated on polysaccharides and steroidal saponins, resulting in a large waste of Polygonatum resources

And at present the pharmacodynamics of Rhizoma Polygonatum and research on its mechanism are still very few, there is extensively Rhizoma Rhizoma Rhizoma Polygonatum without further processing on the market, and the health care product that takes Rhizoma Rhizoma Polygonatum as raw material is relatively rare, in view of the current situation, it is necessary to carry out in-depth development and utilization of Polygonatum The health benefits of the