Gel for treating cervical erosion and injury with rhEGF (Recombinant Human Epidermal Growth Factor) and preparation method of gel

A technology of cervical erosion and gel, which is applied in the field of medicine to achieve the effect of simple preparation process, short healing time and inhibition of pathogen reproduction

Inactive Publication Date: 2017-06-06
郭燕立
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But this literature does not provide a kind of medicine that can be used for clinically, effective to the treatment of common cervicitis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] In the embodiment of the present invention, a gel for treating cervical erosion and injury by using rhEGF, the raw materials in parts by weight include: 3 parts of rhEGF, 1 part of KGF, 3 parts of Baiying extract, 3 parts of Baixianpi extract, 1 part of Sophora flavescens extract, 2 parts of Baiwei extract, 3 parts of Kochia scoparia extract, 2 parts of Hedyotis diffusa extract, 3 parts of Aescin extract, 3 parts of Bletilla striata extract, white Maca extract 3 servings.

[0041] A preparation method of a gel for treating cervical erosion and damage by using rhEGF, comprising the following steps:

[0042] 1) Extracting Baiying in a supercritical extraction device to obtain Baiying extract; the extraction pressure is 15MPa, the temperature is 30°C, static extraction is performed, and the extraction time is 1h. The preparation process of white fresh bark extract, Sophora flavescens extract, Bai Wei extract, Kochia scoparia extract, Hedyotis diffusa extract, Aescin extra...

Embodiment 2

[0045] In the embodiment of the present invention, a gel for treating cervical erosion and injury by using rhEGF, the raw materials in parts by weight include: 8 parts of rhEGF, 5 parts of KGF, 20 parts of Baiying extract, 20 parts of Baixianpi extract, 8 parts of Sophora flavescens extract, 12 parts of Baiwei extract, 25 parts of Kochia scoparia extract, 12 parts of Hedyotis diffusa extract, 25 parts of Aescin extract, 25 parts of Bletilla striata extract, and white Maca extract 25 servings.

[0046] A preparation method of a gel for treating cervical erosion and damage by using rhEGF, comprising the following steps:

[0047] 1) Extracting Baiying in a supercritical extraction device to obtain Baiying extract; the extraction pressure is 30MPa, the temperature is 50°C, static extraction is performed, and the extraction time is 6h. The preparation process of white fresh bark extract, Sophora flavescens extract, Bai Wei extract, Kochia scoparia extract, Hedyotis diffusa extract...

Embodiment 3

[0050] In the embodiment of the present invention, a gel for treating cervical erosion and injury by using rhEGF, the raw materials in parts by weight include: 4 parts of rhEGF, 2 parts of KGF, 4 parts of Baiying extract, 4 parts of Baixian Cortex extract, 1 part of Sophora flavescens extract, 3 parts of Baiwei extract, 4 parts of Kochia scoparia extract, 3 parts of Hedyotis diffusa extract, 4 parts of Aescin extract, 4 parts of Bletilla striata extract, white Maca extract 3 parts, seabuckthorn seed oil 20 parts, locust tree essential oil 2 parts, placenta 0.2 parts.

[0051] A preparation method of a gel for treating cervical erosion and damage by using rhEGF, comprising the following steps:

[0052] 1) Extracting Baiying in a supercritical extraction device to obtain Baiying extract; the extraction pressure is 20MPa, the temperature is 35°C, static extraction is performed, and the extraction time is 2h. The preparation process of white fresh bark extract, Sophora flavescens...

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PUM

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Abstract

The invention discloses a gel for treating cervical erosion and injury with rhEGF (Recombinant Human Epidermal Growth Factor) and a preparation method of the gel. The gel comprises the following raw materials in parts by weight: 3-8 parts of a rhEGF, 1-5 parts of a KGF (Cell Growth Factor), 3-20 parts of a solanum lyratum extract, 3-20 parts of a cortex dictamni extract, 1-8 parts of a sophora flavescens extract, 2-12 parts of a cynanchum atratum extract, 3-25 parts of a kochia scoparia extract, 2-12 parts of an oldenlandia diffusa extract, 3-25 parts of a paris polyphylla extract, 3-25 parts of a bletilla striata extract, 3-25 parts of a white maca extract as well as 20-50 parts of seabuckthorn seed oil, 2-10 parts of sophora japonica essential oil and 0.2-2 parts of placentin. The preparation method comprises the following steps: weighing the raw materials according to the weight parts, and uniformly mixing and stirring, thereby obtaining the gel. The gel disclosed by the invention is high in antibacterial property, and has a good effect of remedying vaginal mucosa and cervical erosion and injury of females. The gel is short in treatment time, rapid in treatment, free of toxin, irritation or hypersensitivity to vaginal mucosa, simple in preparation process, simple in material obtaining and applicable to industrial production.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a gel for treating cervical erosion and damage by using rhEGF and a preparation method thereof. Background technique [0002] Women's cervical erosion, commonly referred to as chronic cervicitis, is a common and frequently-occurring disease in many women, and its prevalence accounts for about 70% of the total number of adult women. With reasonable and effective treatment, the condition will change from mild to moderate to severe, and may even develop into cervical atypical hyperplasia, eventually leading to the occurrence of cervical cancer. In the prior art, no ideal treatment method has been found for the treatment of cervical erosion at home and abroad. Although there are hundreds of gynecological lotions, flushing agents, suppositories, and gels, including oral preparations, they cannot finally solve the original problem. Especially for the treatment of moderate and above c...

Claims

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Application Information

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IPC IPC(8): A61K38/18A61K9/06A61P15/00A61P15/02A61K35/50A61K36/898
CPCA61K9/0034A61K9/06A61K35/50A61K36/11A61K36/185A61K36/27A61K36/31A61K36/489A61K36/748A61K36/75A61K36/81A61K36/896A61K36/898A61K38/1808A61K38/1825A61K2236/37A61K2300/00
Inventor 不公告发明人
Owner 郭燕立
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