Low-temperature plasma-induced thermo-acoustic imaging method

A low-temperature plasma and thermoacoustic imaging technology, applied in the directions of ultrasound/sonic/infrasound image/data processing, sonic diagnosis, infrasound diagnosis, etc. Effect

Pending Publication Date: 2017-06-13
CHINA UNIV OF PETROLEUM (EAST CHINA)
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Problems solved by technology

The current clinical imaging methods for disease diagnosis, such as X-ray, CT, ultrasound, and MRI, can only detect tumors of a certain size, causing most patients to miss the best time for early tumor detection and early treatment. Therefore, research and development of early screening and The methods and technologies of early diagnosis have always been the focus of attention and research at home and abroad.

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Embodiment Construction

[0022] The present invention will be further described below with reference to the accompanying drawings and specific embodiments.

[0023] In the pulsed low-temperature plasma jet, locally ionized noble gas ions form a "single plasma bullet" under the action of a single pulse, which generates local charge separation in space and excites a space electric field. The space electric field propagates forward in the jet, and is coupled into a tiny area on the surface of the measured medium through the plasma channel, inducing electromagnetic energy into the interior of the target body, causing electro-thermal-acoustic effects.

[0024] On the other hand, because the gas breakdown process of the low-temperature plasma jet is mainly based on photoionization, strong photons are generated inside the jet, and the frequency of the light wave is determined by the working gas and the ambient gas, mainly in the ultraviolet band. This part of the photons is injected into the target body, whi...

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Abstract

The invention discloses a low-temperature plasma-induced thermo-acoustic imaging method and particularly relates to a pulse low-temperature plasma-induced thermo-acoustic coupling functional imaging method in the field of biomedical imaging. A nanosecond pulse-excited 'low-temperature plasma jet' acts on a biological tissue, and low-temperature plasma induces pulse energy to the inside of the tissue; and electrical impedance of a normal tissue and a pathological tissue and absorption coefficients on a jet spectrum are different, so that absorption on energy of the plasma jet is also different. The biological tissue absorbs the energy of the plasma jet to generate a heat effect, transient thermal expansion is caused, and a thermo-elastic high-frequency ultrasonic signal is excited. The signal carries the information of the electrical impedance in the tissue and the absorption strength on the jet spectrum; a heat sound source image related to the electrical impedance and the spectrum absorption coefficient can be obtained in micron scale by adopting a sound source reconstruction algorithm; and thus, high-resolution and high-contrast biological tissue medical imaging is provided for early diagnosis of a disease.

Description

technical field [0001] The invention relates to a low-temperature plasma-induced thermoacoustic imaging method, in particular to a pulsed low-temperature plasma-induced high-resolution functional imaging method suitable for biomedical applications. Background technique [0002] Medical imaging technology, especially functional medical imaging technology, occupies an important position and role in health engineering and early diagnosis of diseases. At present, the imaging methods used in clinical diagnosis of diseases, such as X-ray, CT, ultrasound, and MRI, can only detect lumps of a certain size, resulting in most patients missing the best time for early detection and early treatment of tumors. The methods and techniques of early diagnosis have always been the areas of concern and key research at home and abroad. [0003] The "electromagnetic (optical) thermoacoustic imaging" of biological tissue is sensitive to the dielectric spectrum of biological tissue, and has the cha...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00A61B5/053A61B5/05A61B8/00
CPCA61B5/0075A61B5/0095A61B5/05A61B5/053A61B8/52A61B8/5261
Inventor 郭亮姜文聪董范青李林波
Owner CHINA UNIV OF PETROLEUM (EAST CHINA)
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