Preparation for scalds and burns and preparation method of preparation

A preparation and gel technology, applied in the field of medicine, can solve the problems of increased treatment cost, single action, increased adverse reactions and side effects, etc., and achieves the advantages of accelerating wound healing, rigorous formulation, and improving solubility and dispersion uniformity. Effect

Inactive Publication Date: 2017-08-18
广西大海阳光药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] The purpose of the present invention is to provide a preparation for scalds and burns and a preparation method thereof for western medicines to treat scalds and burns.

Method used

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  • Preparation for scalds and burns and preparation method of preparation
  • Preparation for scalds and burns and preparation method of preparation
  • Preparation for scalds and burns and preparation method of preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A kind of preparation method that is used for the preparation of scald, burn preparation gel, comprises the following steps:

[0038] S1: Weigh the components according to the following weight: comfrey 20kg, rhubarb 20kg, cork 10kg, burnet 30kg, honeysuckle 10kg, knotweed 20kg, spirit herb 15kg, borneol 3kg, menthol 2kg, carbomer 8kg, triethanolamine 11kg, Glycerin 80kg, polysorbate-8018kg, ethyl p-hydroxybenzoate 0.8kg, 95% ethanol 15kg;

[0039] S2: Decoct the seven-flavored Chinese herbal medicines such as comfrey weighed in step S1 with water for 2 times, add 6 times the amount of water for 3 hours for the first time, add 5 times the amount of water for 2 hours for the second time, filter, and combine the filtrates;

[0040] S3: Concentrate the filtrate of step S2 to a clear paste with a relative density of 1.03 at 60°C, add 95% ethanol equivalent to the clear paste, let stand for 12 hours, filter the supernatant to recover ethanol and concentrate to a relative dens...

Embodiment 2

[0044] A kind of preparation method that is used for the preparation of scald, burn preparation gel, comprises the following steps:

[0045] S1: Weigh the components according to the following weights: Comfrey 30kg, Rhubarb 25kg, Phellodendron 15kg, Burnet 35kg, Honeysuckle 15kg, Polygonum cuspidatum 30kg, Ling vanilla 17.5kg, Borneol 4kg, Menthol 3kg, Carbomer 9kg, Triethanolamine 12kg , glycerin 90kg, polysorbate-8019kg, ethyl p-hydroxybenzoate 0.9kg, 95% ethanol 20kg;

[0046] S2: Decoct the seven-flavored Chinese herbal medicines such as comfrey weighed in step S1 with 7 times the amount of water, and decoct twice for 2 hours each time, filter, and combine the filtrates;

[0047] S3: Concentrate the filtrate of step S2 to a clear paste with a relative density of 1.04 at 62°C, add 95% ethanol equivalent to the clear paste, let stand for 15 hours, filter the supernatant to recover ethanol and concentrate to a relative density of 62°C It is the clear ointment of 1.18;

[00...

Embodiment 3

[0051] A kind of preparation method that is used for the preparation of scald, burn preparation gel, comprises the following steps:

[0052] S1: Weigh the components according to the following weights: comfrey 40kg, rhubarb 30kg, cork 20kg, burnet 40kg, honeysuckle 20kg, knotweed 40kg, spirit herb 20kg, borneol 5kg, menthol 4kg, carbomer 10kg, triethanolamine 13kg, Glycerin 90kg, polysorbate-8020kg, ethyl p-hydroxybenzoate 1kg, 95% ethanol 20kg;

[0053] S2: Decoct the seven-flavored Chinese medicinal materials such as comfrey weighed in step S1 with water for 2 times, add 8 times the amount of water for 3 hours for the first time, add 6 times the amount of water for 2 hours for the second time, filter, and combine the filtrates;

[0054] S3: Concentrate the filtrate of step S2 to a clear paste with a relative density of 1.05 at 63°C, add 95% ethanol equivalent to the clear paste, let it stand for 18 hours, take the supernatant to recover ethanol and concentrate to a relative ...

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Abstract

The invention discloses a preparation for scalds and burns and a preparation method of the preparation. The preparation is prepared from components in parts by weight as follows: 20-60 parts of radix lithospermi, 20-40 parts of rhubarb, 10-30 parts of cortex phellodendri, 30-50 parts of radix sanguisorbae, 10-30 parts of flos lonicerae, 20-60 parts of rhizoma polygoni cuspidati, 15-25 parts of lysimachia foenum-graecum, 3-7 parts of borneol, 2-6 parts of menthol, 8-12 parts of carbomer, 11-15 parts of triethanolamine, 80-120 parts of glycerinum, 18-22 parts of polysorbate-80, 0.8-1.2 parts of ethyl p-hydroxybenzoate and 15-35 parts of 95% ethanol. The preparation has the efficacy of clearing heat, removing toxins, activating blood, removing blood stasis, eliminating swelling, relieving pains and the like and can effectively relieve pains caused by burns and scalds, effectively protect skin wounds against being infected, promote tissue regeneration and accelerate healing of the wounds, no scars are left, and the preparation is convenient to use, cannot make skin sticky, has no irritation to the skin when used and is safe and free of side and toxic effects.

Description

technical field [0001] The invention belongs to the field of medicines, and relates to a traditional Chinese medicine preparation and a preparation method thereof, in particular to a preparation for scalds and burns and a preparation method thereof. Background technique [0002] Burns generally refer to thermal burns, including tissue damage caused by hot liquids (water, soup, oil, etc.), steam, high-temperature gas, flames, hot metal liquids or solids (such as molten steel, steel ingots), etc., mainly involving skin or mucous membranes In severe cases, it can also injure subcutaneous or submucosal tissues, such as muscles, bones, joints and even internal organs. A scald is tissue damage caused by high-temperature liquids (eg, boiling water, hot oil), high-temperature solids (hot metal, etc.), or high-temperature steam. According to the temperature and the length of contact time, burns are clinically divided into: I degree, the main pathological changes are telangiectasia, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/756A61K9/06A61K47/32A61K47/26A61P17/02A61K31/045
CPCA61K9/0014A61K9/06A61K31/045A61K36/185A61K36/30A61K36/355A61K36/704A61K36/708A61K36/739A61K36/756A61K47/26A61K47/32A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 黄大权邓春霞唐新
Owner 广西大海阳光药业有限公司
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