Traditional Chinese medicinal composition and preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and its preparation, can solve the problems of insignificant effect, large toxic and side effects, etc.

Active Publication Date: 2017-09-29
CHANGCHUN INST OF APPLIED CHEMISTRY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] In view of this, the purpose of the present invention is to solve the problem that existing drugs for the treatment of acute gouty arthritis have

Method used

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  • Traditional Chinese medicinal composition and preparation method and application thereof
  • Traditional Chinese medicinal composition and preparation method and application thereof
  • Traditional Chinese medicinal composition and preparation method and application thereof

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preparation example Construction

[0044] The present invention also provides a preparation method of a traditional Chinese medicine composition, comprising:

[0045] A) Phellodendron Phellodendri is added into alcohol solvent for ultrasonic extraction to obtain Phellodendron Phellodendri extract;

[0046] B) adding Atractylodes atractylodis to an alcohol solvent for ultrasonic extraction to obtain an atractylodis extract;

[0047] C) adding Ginkgo biloba to an alcohol solvent for ultrasonic extraction to obtain Ginkgo biloba extract;

[0048] D) Mixing Phellodendron Phellodendri Extract, Atractylodes Atractylodes Extract and Ginkgo Leaf Extract obtained in A), B), and C), to obtain a traditional Chinese medicine composition.

[0049] According to the present invention, the Phellodendron Phellodendri, Atractylodes Rhizoma Atractylodis and Ginkgo biloba are preferably pulverized before supersonic extraction, and alcoholic solvents are used as extraction solvents in A), B), and C), and the alcoholic solvents are...

Embodiment 1

[0055] After crushing 10 parts by weight of Phellodendron Phellodendri, add 8 times the volume of 75% ethanol, conduct ultrasonic extraction at 25-50°C for 1 hour, and obtain Phellodendron Phellodendri extract;

[0056] After crushing 3.5 parts by weight of Atractylodes atractylodis, add 8 times the volume of 75% ethanol, conduct ultrasonic extraction at 25-50° C. for 1 hour, and obtain Atractylodis atractylodis extract;

[0057] After crushing 5.5 parts by weight of ginkgo leaves, add 8 times the volume of 75% ethanol, conduct ultrasonic extraction at 25-50° C. for 1 hour, and obtain a ginkgo leaf extract;

[0058] The traditional Chinese medicine composition is obtained by mixing the Phellodendron Phellodendri extract, Atractylodes atractylodis extract and Ginkgo biloba extract.

Embodiment 2

[0060] After crushing 10 parts by weight of Phellodendron Phellodendri, add 10 times the volume of 75% ethanol, conduct ultrasonic extraction at 25-50°C for 2 hours, and obtain Phellodendron Phellodendri extract;

[0061] After crushing 5 parts by weight of Atractylodes atractylodis, add 10 times the volume of 75% ethanol, conduct ultrasonic extraction at 25-50°C for 2 hours, and obtain Atractylodes atractylodes extract;

[0062] After crushing 5 parts by weight of ginkgo leaves, add 10 times the volume of 75% ethanol, conduct ultrasonic extraction at 25-50° C. for 2 hours, and obtain a ginkgo leaf extract;

[0063] The traditional Chinese medicine composition is obtained by mixing the Phellodendron Phellodendri extract, Atractylodes atractylodis extract and Ginkgo biloba extract.

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Abstract

The invention provides a traditional Chinese medicinal composition and a preparation method thereof. The traditional Chinese medicinal composition is prepared from the following raw materials in parts by weight: 9.5-12 parts of Cortex Phellodendri (Phellodendron chinense and/or Phellodendron amurense), 3-6 parts of Atractylodes lancea and/or Atractylodes chinensis rhizomes, and 4.5-6 parts of ginkgo leaf. The invention also provides a preparation method of the traditional Chinese medicinal composition. In the traditional Chinese medicinal composition, Cortex Phellodendri and ginkgo leaf both have xanthine oxidase inhibiting and anti-inflammatory effects, and Atractylodes lancea and/or Atractylodes chinensis rhizomes have good uric acid excretion promoting and anti-inflammatory effects. The combination of the above three raw materials can reduce uric acid content in human body by inhibiting secretion and promoting excretion, and can effectively relieve joint inflammation, resulting in good therapeutic effect on acute gouty arthritis.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compositions, and in particular relates to a traditional Chinese medicine composition and its preparation method and application. Background technique [0002] Acute gouty arthritis is a metabolic disorder, and its main symptoms are redness, swelling, heat, and pain in the affected joints. When acute gouty arthritis attacks, it can also induce major diseases such as hypertension, atherosclerosis, and liver and kidney damage, which seriously endanger human health. [0003] The pathogenesis of acute gouty arthritis is that purine metabolism in the patient's body is disordered, resulting in increased accumulation of uric acid. Excessive uric acid is deposited in the form of sodium urate crystals in the joints, synovium and surrounding tissues, causing inflammation in this area. Therefore, the anti-inflammatory activity and the activity of inhibiting xanthine oxidase can be used ...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61P19/02A61P19/06A61K36/284A61K36/16
CPCA61K36/16A61K36/284A61K36/756A61K2236/333A61K2300/00
Inventor 刘舒赵芯刘志强刘忠英宋凤瑞郑重
Owner CHANGCHUN INST OF APPLIED CHEMISTRY - CHINESE ACAD OF SCI
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