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Healing promoting type first-aidhemostatic powderand preparation method thereof

A hemostatic powder and the technology of its preparation steps are applied in the field of healing-promoting emergency hemostatic powder and its preparation, which can solve the problems of insufficient strength of blood clots and long healing time, so as to improve local microcirculation, promote cell regeneration, and reduce pain Effect

Inactive Publication Date: 2017-10-10
常州武城服饰有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The technical problem mainly solved by the present invention: Aiming at the problem that traditional hemostatic agents will release a large amount of heat when hemostasis is rapid, and the blood clot formed after hemostasis is not strong enough, and the healing time is long, a healing-promoting emergency hemostatic powder and its preparation are provided method

Method used

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  • Healing promoting type first-aidhemostatic powderand preparation method thereof

Examples

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Effect test

example 1

[0022] Mix pig bones with acetone at a mass ratio of 1:10, soak them at room temperature for 20 hours, take out the defatted pig bones and wash them with 10% hydrogen peroxide for 3 times, then rinse them with deionized water for 3 times, and vacuum freeze-dry the pigs. bone, crush the dried pig bone and place it in a ball mill jar, mill it at 350r / min for 3h, pass through a 200-mesh sieve to get the pig bone powder, place the pig bone powder in a tubular atmosphere furnace, and calcinate at 550°C for 6h, Stand to cool to room temperature, and grind to obtain calcined particles; take deer antler and notoginseng leaves separately, wash and dry, mix and grind notoginseng leaves and velvet antler at a mass ratio of 1:5, pass through a 150-mesh sieve to obtain a mixed ball mill Granules, according to the mass ratio of 1:10, mix the mixed ball-milled granules with deionized water, heat in a water bath at 55°C for 2 hours, filter to obtain the filtrate, and rotary evaporate at 45°C t...

example 2

[0024]Mix pig bones with acetone at a mass ratio of 1:10, soak them at room temperature for 22 hours, take out the defatted pig bones and wash them with 10% hydrogen peroxide for 4 times, then rinse them with deionized water for 4 times, and vacuum freeze-dry the pigs. bone, crush the dried pig bone and place it in a ball mill jar, mill it at 375r / min for 4h, pass through a 200-mesh sieve to get the pig bone powder, place the pig bone powder in a tubular atmosphere furnace, and calcinate it at 575°C for 7h, Stand to cool to room temperature, and grind to obtain calcined particles; take deer antler and notoginseng leaves separately, wash and dry, mix and grind notoginseng leaves and velvet antler at a mass ratio of 1:5, pass through a 150-mesh sieve to obtain a mixed ball mill Granules, according to the mass ratio of 1:10, mix the mixed ball-milled granules with deionized water, heat in a water bath at 57°C for 3 hours, filter to obtain the filtrate, and rotary evaporate at 47°C...

example 3

[0026] Mix pig bones with acetone at a mass ratio of 1:10, soak them at room temperature for 24 hours, take out the defatted pig bones and wash them with 10% hydrogen peroxide for 5 times, then rinse them with deionized water for 5 times, and vacuum freeze-dry the pigs. bone, crush the dried pig bone and place it in a ball mill jar, mill it at 400r / min for 5h, pass through a 200-mesh sieve to get the pig bone powder, place the pig bone powder in a tubular atmosphere furnace, and calcinate at 600°C for 8h, Stand to cool to room temperature, and grind to obtain calcined particles; take deer antler and notoginseng leaves separately, wash and dry, mix and grind notoginseng leaves and velvet antler at a mass ratio of 1:5, pass through a 150-mesh sieve to obtain a mixed ball mill Granules, according to the mass ratio of 1:10, mix the mixed ball-milled granules with deionized water, heat in a water bath at 60°C for 3 hours, filter to obtain the filtrate, and rotary evaporate at 50°C t...

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Abstract

The invention belongs to the technical field of preparation of medicines and particularly relates to healing promoting type first-aidhemostatic powderand a preparation method thereof. Porous hydroxyapatite powder is prepared from pig bone meal,the porous structure of hydroxyapatite can quickly absorb water in blood, the blood is dehydrated quickly, instantaneousgelation is realized, and accordingly, gel is formed quickly. Meanwhile, a wound is effectively covered and shielded with a coverage layer formed by enzymolysis of protein peptide, a particle synergistic effect is achieved with internal hydroxyapatite, and a cross-linked network structure is formed, so that strength of bloodclots is effectively improved. Radix notoginseng extract and deer antler extractcoordinate effectively, the radix notoginseng extract has effects of promoting capillary regeneration and improving local microcirculation, the deer antler extract has effects of enriching proteoglycan, repairing damage to surrounding cells, promoting cell regeneration and reducing pain in a repair area, and the deer antler extract is also compounded withpolypeptide formed through enzymolysis, so that wound healing is promoted effectively.

Description

technical field [0001] The invention belongs to the technical field of medical drug preparation, and in particular relates to a healing-promoting first-aid hemostatic powder and a preparation method thereof. Background technique [0002] The principle of treatment of traumatic blood loss is firstly rapid and effective hemostasis, followed by immediate blood volume replenishment, and finally the treatment of complications of traumatic blood loss. Among them, rapid and effective hemostasis is the first and most important principle in the treatment of traumatic bleeding, especially uncontrollable hemorrhage. If blood loss can be quickly and effectively controlled, blood volume supplementation will be completely unnecessary, and blood transfusions can also be reduced. many complications. At present, it is considered that the more effective hemostatic measures are still gauze packing, pressurized bandaging, and the use of tourniquets, etc., but the pressurized effect of the band...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L24/08A61L24/02A61L24/00
CPCA61L24/0005A61L24/001A61L24/0015A61L24/0036A61L24/02A61L24/08A61L2300/30A61L2300/412A61L2400/04C08L3/02C08L5/08
Inventor 牟建伟季美
Owner 常州武城服饰有限公司
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