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Jujube compound polysaccharide composition as well as preparation method and application thereof

A technology of complex polysaccharides and jujube polysaccharides, applied in the field of medicine, can solve problems such as single function and ineffective immunity

Active Publication Date: 2017-10-24
云南多糖生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation process of the invention adopts the traditional water decoction extraction method, which has a single function and has no obvious effect on improving immunity

Method used

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  • Jujube compound polysaccharide composition as well as preparation method and application thereof
  • Jujube compound polysaccharide composition as well as preparation method and application thereof
  • Jujube compound polysaccharide composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] The invention is prepared from the following raw materials: jujube polysaccharide extract, wolfberry polysaccharide extract, white fungus polysaccharide extract, neutral notoginseng polysaccharide extract and pharmaceutically acceptable pharmaceutical auxiliary materials. Pharmaceutical excipients include sucrose, starch, maltodextrin, honey, sodium benzoate, ethyl paraben, magnesium stearate, protein sugar, etc.

[0065] The jujube composite polysaccharide composition of the present invention comprises 0.5-5 kg ​​of jujube polysaccharide extract, 0.5-5 kg ​​of wolfberry polysaccharide extract, 0.5-5 kg ​​of white fungus polysaccharide extract, and 0-5 kg ​​of neutral notoginseng polysaccharide extract. Medicinal excipients, mixed evenly, adding 95% ethanol in an appropriate amount, passed through a 14-mesh sieve to granulate, dried, passed through a 20-mesh sieve for sorting, and packed into 1000 bags. Sub-packaging is prepared into oral dosage forms such as granules, ...

Embodiment 2

[0088] Embodiment 2 jujube compound polysaccharide granule

[0089]

[0090] Add an appropriate amount of maltodextrin, mix well, add an appropriate amount of 95% ethanol, pass through a 14-mesh sieve to granulate, dry, pass through a 20-mesh sieve for sorting, and pack into 1000 bags.

[0091] The preparation methods of jujube polysaccharide extract, wolfberry polysaccharide extract, white fungus polysaccharide extract and neutral notoginseng polysaccharide extract in this example are all the same as in Example 1.

Embodiment 3

[0092] Embodiment 3 jujube compound polysaccharide tablet

[0093]

[0094] Add an appropriate amount of maltodextrin, mix well, add an appropriate amount of 95% ethanol, pass through a 14-mesh sieve to granulate, dry, pass through a 20-mesh sieve for sorting, press into tablets, film-coat, and pack.

[0095] The preparation methods of jujube polysaccharide extract, wolfberry polysaccharide extract, white fungus polysaccharide extract and neutral notoginseng polysaccharide extract in this example are all the same as in Example 1.

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Abstract

The invention discloses a jujube compound polysaccharide composition as well as a preparation method and application thereof. A jujube polysaccharide, a tremella polysaccharide, a lycium barbarum polysaccharide and a neutral panax notoginseng polysaccharide are extracted from jujube, tremella sporocarp, wolfberry fruits and panax notoginseng separately, wherein the panax notoginseng is the residue after panax notoginseng saponins are extracted; the yields are 6.5-6.9%, 12.0-21.0%, 2.8-4.4% and 0.32-0.42% separately; the content of the polysaccharides is measured to be 48-58%, 37-41%, 28-34% and 80-94% through an anthrone-sulfuric acid method separately. The formula is conducive to people with low immunity and tumor patients for strengthening the immunity, improving the symptoms, such as energielos, weakness and debilitation, appetite reduction, nausea and vomiting, loose stool and diarrhea, restlessness and insomnia and effectively relieving the harm of chemoradiotherapy and operation to the tumor patient.

Description

technical field [0001] The invention belongs to the field of medicine, and relates to a compound polysaccharide composition of jujube and its preparation method and application. Background technique [0002] According to the World Health Organization website (http: / / www.who.int / mediacentre / factsheets / fs297 / zh / ) Cancer Fact Sheet No. 297 in February 2015, cancer is the leading cause of global morbidity and death. Among the 184 countries and regions, the incidence of malignant tumors in China ranks above the middle level in general, accounting for about 21.8% of the global total. With the intensification of population aging and social and economic development, the process of industrialization and urbanization is accelerating, environmental factors and lifestyles are constantly changing, and the situation of cancer prevention and control in my country is severe. [0003] In recent years, with the development of biotechnology, tumor immunotherapy has become the most promising m...

Claims

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Application Information

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IPC IPC(8): A61K31/715A61P37/04A61P25/26A61P25/20A61P1/08A61P1/14A61P1/12A61P39/00A23L31/00A23L33/125A61K8/73A61Q19/00
CPCA23L31/00A23L33/125A23V2002/00A61K8/73A61K31/715A61K36/07A61K36/258A61K36/725A61K36/815A61K2800/10A61Q19/00A23V2250/208A23V2250/50A23V2200/308A23V2200/324A61K2300/00
Inventor 陈彤
Owner 云南多糖生物科技有限公司
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