Veterinary use traditional Chinese immunopotentiator and application thereof

Abstract

The invention belongs to the field of veterinary use medicine, and particularly relates to a veterinary use traditional Chinese immunopotentiator and application thereof. the veterinary use traditional Chinese immunopotentiator is prepared from the following raw materials in parts by weight: 7 to 14 parts of radix angelicae sinensis polysaccharide, 2 to 10 parts of mushroom polysaccharide, 3 to 8 parts of aloe polysaccharide, 10 to 30 parts of polyoxyethylene hydrogenated castor oil, 5 to 15 parts of absolute ethyl alcohol, 20 to 40 parts of ethyl acetate and 10 to 30 parts of water for injection. The veterinary use traditional Chinese immunopotentiator is applied to Newcastle disease inactivated vaccines (La Sota strains); the self immunopotentiation effect of the traditional Chinese medicine is achieved; the defects of conventional adjuvants can be avoided; the immune effect is obviously improved; safety, high efficiency and non-toxicity are realized; meanwhile, the veterinary use traditional Chinese immunopotentiator is prepared into nanoemulsion; the antigen slow release is realized; the immunization period of the vaccine is prolonged; and the vaccine quality is greatly improved.

Description

technical field [0001] The invention belongs to the field of veterinary medicines, in particular to a veterinary vaccine immune enhancer and its application. Background technique [0002] Immunosuppression in livestock and poultry is a common clinical pathological phenomenon, which is seriously harmful to the breeding industry. There are many reasons for poultry immunosuppression, including mycotoxin contamination in feed, irregular use of drugs, especially those containing immunosuppressive ingredients, improper long-term feeding management, environmental stress, etc. Immunosuppression restricts the physiological metabolism of livestock and poultry, affects growth and development, and raises the cost of breeding significantly; on the other hand, the immune system is damaged, organs, tissues and cells participating in the immune response are destroyed, and the presentation of antigens is interfered. The formation of antibodies is inhibited or blocked, and the barrier protec...

AI Technical Summary

Problems solved by technology

Immunosuppression restricts the physiological metabolism of livestock and poultry, affects growth and development, and raises the cost of breeding significantly; on the other hand, the immune system is damaged, organs, tissues and cells participating in the immune response are destroyed, and the presentation of antigens is interfered. The formation of antibodies is inhibited or blocked, and the barrier protection function of the body is weakened or lost, resulting in secondary or concurrent diseases of livestock and poultry, and can also lead to a decline in the ability of livestock and poultry to respond to vaccine immunity, often failing to achieve effective immune level of protection, resulting in failure of immune protection