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Method of extracting refined liver extract paste from pork liver

A technology of pig liver and liver essence, which is applied in the field of preparation of refined liver essence extract from pig liver, which can solve the problems of poor purity, easy precipitation, and instability of liver extract, achieve good water solubility, easy extraction, and reduce impurities Effect

Active Publication Date: 2017-12-15
HENAN AOLITE PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In view of the above situation, in order to overcome the defects of the prior art, the purpose of the present invention is to provide a preparation method for extracting refined liver essence extract from pig liver, which can effectively solve the problem of poor purity of the existing liver extract, i.e. liver extract, easy precipitation, Unstable, not suitable for the production of liquid products such as mixtures

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1: a kind of preparation method of extracting refined liver extract from pig liver, comprises the following steps:

[0021] Step 1: Remove the non-liver tissue from the pig liver, wash it, and grind it with a meat grinder until it becomes muddy or pasty. Weigh 1300g of pig liver, add water to the pig liver, and the amount of water added is the weight of the pig liver 50%, water is the solvent used for extraction;

[0022] Step 2: add hydrochloric acid to the pig liver in step 1, add hydrochloric acid, the amount of hydrochloric acid added is 0.07% of the weight of the pig liver, add water and mix well when adding acid, so that the pH value of the acid solution is 4.0~5.0; after adding acid and water, the whole The ph value of the mixture is 4.0~5.0. Usually, the dissolution of nutrients is better within this ph value range. It is necessary to maintain this weakly acidic environment, but it is not possible to add too much acid to cause digestion and introduce ...

Embodiment 2

[0026] Embodiment 2: a kind of preparation method of extracting refined liver extract from pig liver, comprises the following steps:

[0027] Step 1: Remove the non-liver tissue from the pig liver, wash it, and grind it with a meat grinder until it becomes muddy or pasty. Weigh 1300g of pig liver, add water to the pig liver, and the amount of water added is the weight of the pig liver 60% of the water is the solvent used for extraction;

[0028] Step 2: add hydrochloric acid to the pig liver in step 1, add hydrochloric acid, the amount of hydrochloric acid added is 0.12% of the weight of the pig liver, add water and mix well when adding acid, so that the pH value of the acid solution is 4.0~5.0; The ph value of the mixture is 4~5. Usually, the dissolution of nutrients is better within this ph value range. It is necessary to maintain this weakly acidic environment, but it is not possible to add too much acid to cause digestion and introduce other impurities;

[0029] Step 3: S...

Embodiment 3

[0032] Embodiment 3: a kind of preparation method of extracting refined liver extract from pig liver, comprises the following steps:

[0033] Step 1: Remove the non-liver tissue from the pig liver, wash it, and grind it with a meat grinder until it becomes muddy or pasty. Weigh 1300g of pig liver, add water to the pig liver, and the amount of water added is the weight of the pig liver 55%, water is the solvent used for extraction;

[0034] Step 2: Add 1:1 sulfuric acid to the pig liver in step 1. The volume of 1:1 sulfuric acid is water and the volume of sulfuric acid is 1:1. The amount of sulfuric acid added in 1:1 is 0.1% of the weight of pig liver. When adding acid, add water and mix well , so that the pH value of the acid solution is 4.0~5.0; after adding acid and water, the pH value of the whole mixture is 4~5. Usually, the dissolution of nutrients is better within this pH value range. It is necessary to maintain this weakly acidic environment, but it cannot Adding too m...

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PUM

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Abstract

The invention relates to the field of traditional Chinese medicines, and particularly relates to a method of extracting refined liver extract paste from pork liver. The method comprises the procedures of water extraction, concentration, ethanol precipitation, water precipitation and the like. The pork liver is minced into paste, so as to obtain an effective component to extract the refined liver extract paste more easily; the amount of added acid is controlled to be 0.1% that of the pork liver, so that ph of a mixture is 4-5, a digestion phenomenon (impurity increase) caused by excessive acid addition is prevented, and the ph of 4-5 makes the effective component dissolve out most easily; extraction temperature is controlled at 90-95DEG C, an intermittent agitating manner is adopted for assistance, and a reduced pressure concentration manner maintains the effective component most; ethanol precipitation can help clearly prepare and purify the effective component, thereby further reducing impurities; and ethanol paste is added with water for water precipitation, so that substances that cannot be disolved in the water are filtered to prevent precipitate in a preparation with liquid. The liver extract paste prepared by the method has higher purity, better water solubility and higher stability, and can be added in liquid or solid food, healthcare products, medicines and the like.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a preparation method for extracting refined liver extract from pig liver. Background technique [0002] Ganjing paste is a refined extract of animal liver, mainly pigs, cattle, sheep, especially pigs. Pork liver is the liver of the pig Sus scrofa domestica Brisson. After slaughtering, take the liver by caesarean section, and use it fresh or refrigerated. Theory of traditional Chinese medicine: It has the effect of nourishing the liver and improving eyesight, nourishing blood and strengthening the spleen; it is mainly used to treat liver deficiency, dizziness, night blindness, blood deficiency and chlorosis, malnutrition in children, beriberi edema, edema, chronic dysentery, prolapse of the anus, leukorrhea. 100 grams of pork liver contains: 21.3 grams of protein, 4.5 grams of fat, 1.4 grams of carbohydrates, 11 mg of calcium, 270 mg of phosphorus, 25.0 mg of iron, 5....

Claims

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Application Information

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IPC IPC(8): A61K35/407A61K9/06A61P7/06
CPCA61K9/06A61K35/407
Inventor 秦兴国李晓旭屈淑灵
Owner HENAN AOLITE PHARMA
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