Biocolloid dispersant and preparation method thereof

A technology of biological colloid and dispersant, which is applied in the field of medical surgical medicine and its preparation, can solve the problems of debridement performance, relieve wound pain, and the speed of wound healing is not enough to meet the expected requirements, achieve excellent moisturizing effect, and improve debridement performance , the effect of accelerating the healing speed

Inactive Publication Date: 2017-12-22
苏州汇涵医用科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] However, the products obtained by the above two patent schemes are found in medical clinical use: in terms of debridement performance, wound pain relief and wound healing speed, it is not enough to meet the expected requirements, so it is necessary to improve, as follows The technical solution introduced is produced under this background

Method used

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  • Biocolloid dispersant and preparation method thereof
  • Biocolloid dispersant and preparation method thereof
  • Biocolloid dispersant and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A) 0.45g silver nitrate crystals of analytically pure grade are added into 15g deionized water and stirred evenly to obtain 15.45g silver nitrate crystal solution;

[0031] B) 0.25g of glycerin was added into 12g of distilled water and stirred evenly to obtain 12.25g of dilute glycerin solution;

[0032] C) 1g menthol is added into 15g distilled water and stirred evenly to obtain 16g menthol solution;

[0033] D) Stir the 12.25g dilute glycerin solution obtained by step B) and the 16g menthol solution obtained by step C) to obtain a 28.25g mixed solution;

[0034] E) the 15.45g silver nitrate crystal solution obtained by step A) is stirred with the 28.25g mixed solution obtained by step D), to obtain 43.70g silver nitrate crystal solution mixed solution;

[0035] F) 0.1g phosphoric acid was added to the 43.70g silver nitrate crystal solution mixed solution obtained by step E) and acidified for 30min, and the pH value was adjusted to 2 to obtain the acidified 43.80g sil...

Embodiment 2

[0042] A) the silver nitrate crystal of 0.01g analysis grade is added in 12g distilled water and stirs, obtains 12.01g silver nitrate crystal solution;

[0043] B) Add 0.1 g of glycerin to 10 g of deionized water and stir well to obtain 10.1 g of dilute glycerin solution;

[0044] C) 0.5g menthol is added into 18g distilled water and stirred evenly to obtain 18.5g menthol solution;

[0045] D) Stir the 10.1g dilute glycerin solution obtained by step B) with the 18.5g menthol solution obtained by step C), to obtain 28.6g mixed solution;

[0046] E) the 12.01g silver nitrate crystal solution obtained by step A) is stirred with the 28.6g mixed solution obtained by step D), to obtain 40.61g silver nitrate crystal solution mixed solution;

[0047] F) 0.25g phosphoric acid was added to the 40.61g silver nitrate crystal solution mixed solution obtained by step E) and acidified for 20min, and the pH value was adjusted to 1.5 to obtain the acidified 40.86g silver nitrate crystal solut...

Embodiment 3

[0054] A) the silver nitrate crystal of 0.23g analysis grade is added in 10g distilled water and stirs, obtains 10.23g silver nitrate crystal solution;

[0055] B) 0.4g glycerol was added into 15g deionized water and stirred evenly to obtain 15.4g dilute glycerin solution;

[0056] C) 0.7g menthol is added into 20g deionized water and stirred evenly to obtain 20.7g menthol solution;

[0057] D) Stir the 15.4g dilute glycerin solution obtained by step B) with the 20.7g menthol solution obtained by step C), to obtain a 36.1g mixed solution;

[0058] E) the 10.23g silver nitrate crystal solution obtained by step A) is stirred with the 36.1g mixed solution obtained by step D), to obtain 46.33g silver nitrate crystal solution mixed solution;

[0059] F) 0.4g citric acid was added to the 46.33g silver nitrate crystal solution mixed solution obtained by step E) for acidification treatment for 10min, and the pH value was adjusted to 1.8 to obtain the acidified 46.73g silver nitrate c...

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Abstract

The invention relates to a biocolloid dispersant and a preparation method thereof. The preparation method comprises the following steps: adding silver nitrate crystals into pure water, and uniformly stirring, so that silver nitrate crystal solution is obtained; adding glycerol into the pure water, and uniformly stirring, so that dilute glycerol solution is obtained; adding menthol into the pure water, and uniformly stirring, so that menthol solution is obtained; uniformly stirring the glycerol solution with the menthol solution, so that mixed liquor is obtained; uniformly stirring the silver nitrate crystal solution with the mixed liquor, so that silver nitrate crystal solution mixed liquor is obtained; adding ternary acid into the silver nitrate crystal solution mixed liquor, and carrying out acidifying treatment, so that the silver nitrate crystal solution mixed solution is obtained; adding tartaric acid solution into the silver nitrate crystal solution mixed solution, and uniformly stirring, so that standby solution is obtained; adding sodium alginate into the pure water, heating, dissolving and stirring, then adding a penetrating agent, and stirring, so that a stabilizer is obtained; and adding the standby solution into a stirring container filled with the pure water, stirring, adding the stabilizer, continuously stirring, and sequentially standing, filtering and filling, so that the biocolloid dispersant finished product is obtained.

Description

technical field [0001] The invention relates to a biological colloid dispersant, which is applicable to various tissue wounds, prevents and controls wound infection, and promotes wound healing, and also relates to a preparation method of the biological colloid dispersant, which belongs to the field of medical surgical medicine and its preparation technology. Background technique [0002] Recognized both at home and abroad, such as wound infections caused by burns, scalds, and open wounds, are mainly sulfadiazine silver cream (also known as "sulfadiazine ointment") or suspensions. In addition, mainly silver ions, the drug is widely used clinically. [0003] The invention patent authorization announcement number CN100560057C recommended "Wound-protecting liquid and its preparation method" objectively pointed out the deficiency of the above-mentioned silver sulfadiazine cream and made up for it. The formula of this patent is: every 1000g of finished liquid contains: silver ion...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/38A61K9/08A61K47/36A61K47/12A61K47/10A61K47/04A61P17/00A61P17/02A61P29/00A61P31/02A61K31/045
CPCA61K33/38A61K9/08A61K31/045A61K47/02A61K47/10A61K47/12A61K47/36A61K2300/00
Inventor 冯胜权冯永良
Owner 苏州汇涵医用科技发展有限公司
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