Method for preparing 5-hydroxymethyl furfural from glucose

Abstract

The invention discloses a method for preparing 5-hydroxymethyl furfural from glucose. The method comprises the following steps: (1) adding the glucose, choline chloride, a solid acid catalyst and an organic solvent into a high pressure reaction kettle, heating to 150 to 210 DEG C to perform reaction at a stirring speed of 200 to 800 rpm and under the nitrogen atmosphere of 1 to 5 MPa, thus obtaining a solid-liquid mixture; and (2) enabling the material of step (1) to be reacted circularly or centrifuged to recycle the solid acid catalyst, and extracting the 5-hydroxymethyl furfural in situ inthe reaction kettle by virtue of the organic solvent. The method provided by the invention has the advantages of simple operation, easy industrialization, and environment friendliness.

Description

technical field [0001] The invention belongs to the technical field of 5-hydroxymethylfurfural synthesis, and in particular relates to a method for preparing 5-hydroxymethylfurfural from glucose. Background technique [0002] 5-Hydroxymethylfurfural is an important platform compound, which contains a furan ring, an aldehyde group and a hydroxymethyl group, so it can undergo reactions such as hydrogenation, oxidative dehydrogenation, esterification, halogenation, polymerization, and hydrolysis Prepare a variety of derivatives, which are widely used in medical, plastic, biofuel and other fields. [0003] HMF is mainly produced by removing three molecules of water from sugars such as glucose and fructose under the action of a catalyst. Compared with fructose, glucose is more abundant in nature and cheaper, which can realize the large-scale production of 5-hydroxymethylfurfural. [0004] The reaction system for preparing 5-hydroxymethylfurfural from glucose at home and abroad ...

AI Technical Summary

Problems solved by technology

In the ionic liquid reaction system, the catalyst has good catalytic performance, but the ionic liquid is very expensive, and there are still a series of problems such as the difficulty of catalyst recovery; however, in the water-organic solvent two-phase reaction system, 5-hydroxymethyl Furfural is extremely unstable and easily further converted into downstream products such as levulinic acid

[0005] At present, the catalysts for preparing 5-hydroxymethylfurfural from glucose still have disadvantages such as complex preparation process, unfriendly environment and difficult recycling.

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