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QingHao nidation patch, preparation method thereof and application thereof in embryo transplantation

A technology of embryo transfer and bed paste, which is applied in the field of reproductive medicine and can solve problems such as the unsatisfactory implantation rate of transferred embryos

Inactive Publication Date: 2018-02-23
祁青昊
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

At present, the unsatisfactory implantation rate of transplanted embryos has become a bottleneck restricting the development of various clinical assisted pregnancy technologies, and the key factors are endometrial receptivity and corpus luteum function

Method used

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  • QingHao nidation patch, preparation method thereof and application thereof in embryo transplantation
  • QingHao nidation patch, preparation method thereof and application thereof in embryo transplantation
  • QingHao nidation patch, preparation method thereof and application thereof in embryo transplantation

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Embodiment

[0015] Refer to the Clinical Diagnosis and Treatment Guidelines for Assisted Reproductive Technology and Sperm Bank Volume, 1, normal sexual life, who have not been pregnant for more than 1 year without contraception. 2. Those who have ever been pregnant, have not been contraceptive and have been infertile for 1 year in a row. 30 patients who received in vitro fertilization-embryo transfer (IVF-ET) assisted pregnancy in our hospital from June 2016 to October 2016 were selected and divided into observation group (Qinghao implantation sticker combined with progesterone support group) according to the random number table method. ) and the control group (progesterone-only support group). There were 15 cases in the observation group, all aged 26-35 years, with an average age of 33.2 years; 15 cases in the control group, all aged 26.3-36.5 years old, with an average age of 33.8 years. There was no significant difference in age between the two groups (p>0.05).

[0016] method

[0...

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Abstract

The invention discloses a QingHao nidation patch, a preparation method thereof and application thereof in embryo transplantation. The QingHao nidation patch is prepared from radix polygoni multiflori,radix dipsaci, semen cuscutae and rhizoma atractylodis macrocephalae. In the formula, radix polygoni multiflori preparata can nourish the liver and kidneys and enrich essence and blood; radix dipsacican nourish the liver and kidneys and regulate blood vessels; semen cuscutae can warm the kidneys to replenish essence and tonify kidney Yin-Yang, and is warm without dryness and nourishing without stagnation; semen cuscutae flavonoids can achieve the effect of maintaining early pregnancy by regulating the endocrine-immune network balance of the maternal-fetal interface and also can achieve the effect of preventing miscarriages by regulating the proliferation and apoptosis of trophocytes; rhizoma atractylodis macrocephalae can replenish Qi to invigorate the spleen to enrich the source of Qi and blood; thus, the purpose of invigorating the kidneys for pregnancy is achieved. The QingHao nidation patch can be used for improving the progesterone level and the ongoing pregnancy rate, so that the success rate of embryo transplantation is increased, and the QingHao nidation patch makes a contribution to the assisted reproduction subject.

Description

technical field [0001] The invention relates to the field of reproductive medicine, in particular to a Qinghao implantation patch, a preparation method thereof, and an application in embryo transplantation. Background technique [0002] Due to the liberalization of my country's two-child policy and the increasing number of infertile patients, the number of patients receiving in vitro fertilization (ivf-et) is also increasing year by year. Therefore, improving the clinical pregnancy rate and continuing pregnancy rate of embryos has become the focus of today's assisted reproduction field. question. [0003] Embryo transfer is a more effective method to solve the above problems at present, and the success of implantation is the most critical step in IVF-ET technology. At present, the unsatisfactory implantation rate of transferred embryos has become a bottleneck restricting the development of various assisted reproductive technologies in clinical practice. The key factors are e...

Claims

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Application Information

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IPC IPC(8): A61K36/704A61K9/70A61P15/08
CPCA61K9/70A61K36/185A61K36/284A61K36/39A61K36/43A61K36/704A61K2300/00
Inventor 祁青昊
Owner 祁青昊
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