Compound nicotine salt and preparation method thereof
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- 东莞济信生物科技有限公司
- Publication Date
- 2018-03-20
- Estimated Expiration
- Not applicable · inactive patent
Abstract
Description
technical field
[0001] The invention belongs to the technical field of nicotine salts, and in particular relates to a compound nicotine salt and a preparation method thereof. Background technique
[0002] Nicotine, also known as nicotine, is a neurotoxic agent. The mechanism of toxicity is mainly the N-choline response system to the central nervous system and cholinergic nerves. There will be a burning sensation and a local irritation to the digestive tract.
[0003] Nicotine salts are characterized by the interaction between nicotine in ionic form and the coform (e.g., acid) in ionic form via the transfer of one or more protons from the coformer donor to the nicotine acceptor Nicotine form. The structure of nicotine is such that it contains two nitrogen atoms capable of accepting protons from the conformant, and therefore, it can exist in a given sample in non-protonated, monoprotonated and / or diprotonated forms.
[0004] In tobacco, nicotine mostly exists in the form of...